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LIM Kinase (LIMK)

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  1. SR 7826, Inhibitor of LIM domain kinase 1
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    SR 7826, Inhibitor of LIM domain kinase 1
    CAS: 1219728-20-7 PubChem CID: 45381385 Formula: C22H21N5O2 Molecular Weight: 387.43
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    In Stock Item #: S286759
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    IUPAC Name
    1-(2-hydroxyethyl)-3-[4-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl]-1-phenylurea
    SMILES
    CC1=CNC2=NC=NC(=C12)C3=CC=C(C=C3)NC(=O)N(CCO)C4=CC=CC=C4
    InChIKey
    WQAGVQVBDHOHRD-UHFFFAOYSA-N
    InChI
    1S/C22H21N5O2/c1-15-13-23-21-19(15)20(24-14-25-21)16-7-9-17(10-8-16)26-22(29)27(11-12-28)18-5-3-2-4-6-18/h2-10,13-14,28H,11-12H2,1H3,(H,26,29)(H,23,24show more
    Synonyms
    N-(2-Hydroxyethyl)-N'-[4,5-methyl-7H-pyrrolo[2,3-d]pyrimidine-4-yl)phenyl]-N-phenylurea | SR7826 | SR-7826
  2. LIMKi 3, Inhibitor of LIM domain kinase 1;Inhibitor of LIM domain kinase 2
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    LIMKi 3, Inhibitor of LIM domain kinase 1;Inhibitor of LIM domain kinase 2
    CAS: 1338247-35-0 Formula: C17H14Cl2F2N4OS Molecular Weight: 431.29
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    In Stock Item #: L288407
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    Technical Identifiers
    IUPAC Name
    N-[5-[2-(2,6-dichlorophenyl)-5-(difluoromethyl)pyrazol-3-yl]-1,3-thiazol-2-yl]-2-methylpropanamide
    SMILES
    CC(C)C(=O)NC1=NC=C(S1)C2=CC(=NN2C3=C(C=CC=C3Cl)Cl)C(F)F
    InChIKey
    IVUGBSGLHRJSSP-UHFFFAOYSA-N
    InChI
    1S/C17H14Cl2F2N4OS/c1-8(2)16(26)23-17-22-7-13(27-17)12-6-11(15(20)21)24-25(12)14-9(18)4-3-5-10(14)19/h3-8,15H,1-2H3,(H,22,23,26)
    Synonyms
    J-523083 | LIMKI-3 (BMS-5) | GTPL9839 | HMS3743I19 | BMS 5 | LIM Kinase Inhibitor I | N-[5-[2-(2,6-dichlorophenyl)-5-...
  3. T 5601640
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    T 5601640
    CAS: 924473-59-6 EC Number: 110-093-0 PubChem CID: 9438169 Formula: C19H14F3N3O3 Molecular Weight: 389.33
    ≥99%(HPLC)
    In Stock Item #: T287261
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    IUPAC Name
    3-methyl-N-[3-[[3-(trifluoromethyl)phenyl]carbamoyl]phenyl]-1,2-oxazole-5-carboxamide
    SMILES
    CC1=NOC(=C1)C(=O)NC2=CC=CC(=C2)C(=O)NC3=CC=CC(=C3)C(F)(F)F
    InChIKey
    XVOKFRPKSAWELK-UHFFFAOYSA-N
    InChI
    1S/C19H14F3N3O3/c1-11-8-16(28-25-11)18(27)24-14-6-2-4-12(9-14)17(26)23-15-7-3-5-13(10-15)19(20,21)22/h2-10H,1H3,(H,23,26)(H,24,27)
    Synonyms
    T56-LIMKi | 3-Methyl-N-[3-[[[3-(trifluoromethyl)phenyl]amino]carbonyl]phenyl]-5-isoxazolecarboxamide | 3-methyl-N-(3-...
  4. TH 257
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    TH 257
    CAS: 2244678-29-1 PubChem CID: 137796294 Formula: C24H26N2O3S Molecular Weight: 422.54
    ≥98%(HPLC)
    In Stock Item #: T287707
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    IUPAC Name
    N-benzyl-N-butyl-4-(phenylsulfamoyl)benzamide
    SMILES
    CCCCN(CC1=CC=CC=C1)C(=O)C2=CC=C(C=C2)S(=O)(=O)NC3=CC=CC=C3
    InChIKey
    VNCIWNGCMAKKEO-UHFFFAOYSA-N
    InChI
    1S/C24H26N2O3S/c1-2-3-18-26(19-20-10-6-4-7-11-20)24(27)21-14-16-23(17-15-21)30(28,29)25-22-12-8-5-9-13-22/h4-17,25H,2-3,18-19H2,1H3
    Synonyms
    N-Butyl-4-[(phenylamino)sulfonyl]-N-(phenylmethyl)benzamide
  5. 3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide
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    3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide
    CAS: 67795-42-0 EC Number: 154-574-3 PubChem CID: 613528 Formula: C10H11N3OS Molecular Weight: 221.28
    ≥98%
    In Stock Item #: W418014
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    Technical Identifiers
    IUPAC Name
    3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide
    SMILES
    CC1=CC(=NC2=C1C(=C(S2)C(=O)N)N)C
    InChIKey
    SDMLKCQDZJOSDN-UHFFFAOYSA-N
    InChI
    1S/C10H11N3OS/c1-4-3-5(2)13-10-6(4)7(11)8(15-10)9(12)14/h3H,11H2,1-2H3,(H2,12,14)
    Synonyms
    HMS1440A19 | 3-amino-4,6-dimethyl-thieno[2,3-b]pyridine-2-carboxamide | 3-Amino-4,6-dimethylthieno[2,3-b]pyridine-2-c...
  6. BMS-3
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    BMS-3
    CAS: 1338247-30-5 EC Number: 110-685-9 Formula: C17H12Cl2F2N4OS Molecular Weight: 429.27
    ≥98%
    In Stock Item #: B413002
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    Technical Identifiers
    IUPAC Name
    N-[5-[2-(2,6-dichlorophenyl)-5-(difluoromethyl)pyrazol-3-yl]-1,3-thiazol-2-yl]cyclopropanecarboxamide
    SMILES
    C1CC1C(=O)NC2=NC=C(S2)C3=CC(=NN3C4=C(C=CC=C4Cl)Cl)C(F)F
    InChIKey
    YBGGBHCJSAEIAS-UHFFFAOYSA-N
    InChI
    1S/C17H12Cl2F2N4OS/c18-9-2-1-3-10(19)14(9)25-12(6-11(24-25)15(20)21)13-7-22-17(27-13)23-16(26)8-4-5-8/h1-3,6-8,15H,4-5H2,(H,22,23,26)
  7. CRT 0105950
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    CRT 0105950
    CAS: 1661845-86-8 Formula: C21H16ClN3OS Molecular Weight: 393.89
    ≥98%(HPLC)
    Out of Stock Item #: C286999
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    Technical Identifiers
    IUPAC Name
    4-[[5-[3-(2-chloro-4-methylphenyl)pyridin-4-yl]-1,3-thiazol-2-yl]amino]phenol
    SMILES
    CC1=CC(=C(C=C1)C2=C(C=CN=C2)C3=CN=C(S3)NC4=CC=C(C=C4)O)Cl
    InChIKey
    QYDBOFPHPMYWDO-UHFFFAOYSA-N
    InChI
    1S/C21H16ClN3OS/c1-13-2-7-16(19(22)10-13)18-11-23-9-8-17(18)20-12-24-21(27-20)25-14-3-5-15(26)6-4-14/h2-12,26H,1H3,(H,24,25)
    Synonyms
    4-[[5-[3-(2-Chloro-4-methylphenyl)-4-pyridinyl]-2-thiazolyl]amino]phenol
  8. LIMKi 3, Inhibitor of LIM domain kinase 1;Inhibitor of LIM domain kinase 2
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    LIMKi 3, Inhibitor of LIM domain kinase 1;Inhibitor of LIM domain kinase 2
    CAS: 1338247-35-0 Formula: C17H14Cl2F2N4OS Molecular Weight: 431.29
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: L421279
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    Technical Identifiers
    IUPAC Name
    N-[5-[2-(2,6-dichlorophenyl)-5-(difluoromethyl)pyrazol-3-yl]-1,3-thiazol-2-yl]-2-methylpropanamide
    SMILES
    CC(C)C(=O)NC1=NC=C(S1)C2=CC(=NN2C3=C(C=CC=C3Cl)Cl)C(F)F
    InChIKey
    IVUGBSGLHRJSSP-UHFFFAOYSA-N
    InChI
    1S/C17H14Cl2F2N4OS/c1-8(2)16(26)23-17-22-7-13(27-17)12-6-11(15(20)21)24-25(12)14-9(18)4-3-5-10(14)19/h3-8,15H,1-2H3,(H,22,23,26)
    Synonyms
    J-523083 | LIMKI-3 (BMS-5) | GTPL9839 | HMS3743I19 | BMS 5 | LIM Kinase Inhibitor I | N-[5-[2-(2,6-dichlorophenyl)-5-...
  9. R-10015
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    R-10015
    CAS: 2097938-51-5 PubChem CID: 129896912 Formula: C20H19ClN6O2 Molecular Weight: 410.86
    ≥96%
    In Stock Item #: R413653
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    Technical Identifiers
    IUPAC Name
    methyl 2-[1-(5-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-yl]-3H-benzimidazole-5-carboxylate
    SMILES
    COC(=O)C1=CC2=C(C=C1)N=C(N2)C3CCN(CC3)C4=NC=NC5=C4C(=CN5)Cl
    InChIKey
    MGRJCGXCUUCOQG-UHFFFAOYSA-N
    InChI
    1S/C20H19ClN6O2/c1-29-20(28)12-2-3-14-15(8-12)26-17(25-14)11-4-6-27(7-5-11)19-16-13(21)9-22-18(16)23-10-24-19/h2-3,8-11H,4-7H2,1H3,(H,25,26)(H,22,23,2show more
    Synonyms
    1H-​Benzimidazole-​6-​carboxylic acid,2-​[1-​(5-​chloro-​7H-​pyrrolo[2,​3-​d]​pyrimidin-​4-​yl)​-​4-​piperidinyl]​-​,...
  10. R-10015
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    R-10015
    CAS: 2097938-51-5 PubChem CID: 129896912 Formula: C20H19ClN6O2 Molecular Weight: 410.86
    10mM in DMSO
    In Stock Item #: R422544
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    methyl 2-[1-(5-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-yl]-3H-benzimidazole-5-carboxylate
    SMILES
    COC(=O)C1=CC2=C(C=C1)N=C(N2)C3CCN(CC3)C4=NC=NC5=C4C(=CN5)Cl
    InChIKey
    MGRJCGXCUUCOQG-UHFFFAOYSA-N
    InChI
    1S/C20H19ClN6O2/c1-29-20(28)12-2-3-14-15(8-12)26-17(25-14)11-4-6-27(7-5-11)19-16-13(21)9-22-18(16)23-10-24-19/h2-3,8-11H,4-7H2,1H3,(H,25,26)(H,22,23,2show more
    Synonyms
    1H-​Benzimidazole-​6-​carboxylic acid,2-​[1-​(5-​chloro-​7H-​pyrrolo[2,​3-​d]​pyrimidin-​4-​yl)​-​4-​piperidinyl]​-​,...
  11. T 5601640
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    T 5601640
    CAS: 924473-59-6 EC Number: 110-093-0 PubChem CID: 9438169 Formula: C19H14F3N3O3 Molecular Weight: 389.33
    10mM in DMSO
    In Stock Item #: T426943
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    Technical Identifiers
    IUPAC Name
    3-methyl-N-[3-[[3-(trifluoromethyl)phenyl]carbamoyl]phenyl]-1,2-oxazole-5-carboxamide
    SMILES
    CC1=NOC(=C1)C(=O)NC2=CC=CC(=C2)C(=O)NC3=CC=CC(=C3)C(F)(F)F
    InChIKey
    XVOKFRPKSAWELK-UHFFFAOYSA-N
    InChI
    1S/C19H14F3N3O3/c1-11-8-16(28-25-11)18(27)24-14-6-2-4-12(9-14)17(26)23-15-7-3-5-13(10-15)19(20,21)22/h2-10H,1H3,(H,23,26)(H,24,27)
    Synonyms
    T56-LIMKi;3-Methyl-N-[3-[[[3-(trifluoromethyl)phenyl]amino]carbonyl]phenyl]-5-isoxazolecarboxamide
  12. WAY-248134
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    WAY-248134
    CAS: 67795-42-0 EC Number: 154-574-3 PubChem CID: 613528 Formula: C10H11N3OS Molecular Weight: 221.28
    10mM in DMSO
    In Stock Item #: W425405
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide
    SMILES
    CC1=CC(=NC2=C1C(=C(S2)C(=O)N)N)C
    InChIKey
    SDMLKCQDZJOSDN-UHFFFAOYSA-N
    InChI
    1S/C10H11N3OS/c1-4-3-5(2)13-10-6(4)7(11)8(15-10)9(12)14/h3H,11H2,1-2H3,(H2,12,14)
    Synonyms
    HMS1440A19 | 3-amino-4,6-dimethyl-thieno[2,3-b]pyridine-2-carboxamide | 3-Amino-4,6-dimethylthieno[2,3-b]pyridine-2-c...
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