RuCl(p-cymene)[(R,R)-Ts-DPEN] - ≥99.95% metals basis , CAS No.192139-92-7

CAS: 192139-92-7 Cat. No.: R294384 Molecular Weight: 636.21 EC Number: 664-456-8

GRADE & PURITY ≥99.95% metals basis

Synonyms

Chiralyst Ru636

Storage

Store at 2-8°C

Shipped In

Wet ice

Overview

Product class
M-N, Homogeneous Catalysts, M-C, Arene/Aryl Ligands, Chiral Ligands

Reaction type
Hydrogenation, Asymmetric Reactions, Asymmetric Hydrogenation, Transfer Hydrogenation

Chemical properties

Chemical formula

C31H35N2ClO2SRu

Empirical formula

Ru[(R,R)-TsDPEN](p-cymene)Cl

Molecular weight

636.22

Metal

Ru

Theoretical metal content

16

Physical state

powder

Color
Metal purity

orange

99.95

Applications & references

Synthesis of optically active 4-hydroxy-2,6,6-trimethyl-cyclohex-3-enone derivatives via enantioselective transfer hydrogenation of the corresponding enolethers for the production of (3S,3’S)-astaxantin.

Reference: WO2008 116714

Asymmetric transfer hydrogenation of functionalized ketones for the drug substance synthesis, e.g. rivastigimine for the treatment of Alzheimer’s disease.

Reference: WO2010 0072798

Preparation of optically active aromatic epoxides by asymmetric transfer hydrogenation of α-chlorinated ketones.  

Reference: Tetrah. 2004, 60, 7411 (DOI: 10.1016/j.tet.2004.06.076)

Asymmetric transfer hydrogenation of benzyl with formic acid.

Reference: Org. Lett. 1999, 1, 1119 (DOI: 10.1021/ol990226a)

Specifications

Synonyms

Chiralyst Ru636

Specifications & Purity

≥99.95% metals basis

Storage

Store at 2-8°C

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥99.95% metals basis

Names and Identifiers

• Canonical Smiles: CC(C)c1ccc(C)cc1.Cc2ccc(cc2)S(=O)(=O)N(RuCl)C@@H(C@H(N)c3ccccc3)c4ccccc4
• InChIKey: AZFNGPAYDKGCRB-AGEKDOICSA-M
• INCHI: 1S/C21H21N2O2S.C10H14.ClH.Ru/c1-16-12-14-19(15-13-16)26(24,25)23-21(18-10-6-3-7-11-18)20(22)17-8-4-2-5-9-17;1-8(2)10-6-4-9(3)5-7-10;;/h2-15,20-21H,22H2,1H3;4-8H,1-3H3;1H;/q-1;;;+2/p-1/t20-,21-;;;/m1.../s1
• WGK Germany: 3
• Molecular Weight: 636.21

Chemical and Physical Properties

• Specific Rotation[α]: -116° (C=0.1,CHCl3)
• Melt Point(°C): 215 °C

References

1. Yong Pan, Chaoqin Ren, Jingshu Jin, Yanjun Wang, Sébastien Leveneur, Juncheng Jiang.  (2025)  Acid-base synergetic effect and thermal risk assessment on homogeneous catalytic production of γ-valerolactone with formic acid.  JOURNAL OF LOSS PREVENTION IN THE PROCESS INDUSTRIES,      [PMID:] [10.1016/j.jlp.2025.105636]

2. Xiao-Lin Wang, Qian-Hao Chen, Qi-Hui Ye, Hao Ye, Yu-Ting Zhao, Jing Yang, Yucong Yu, Ming-Bang Wu, Juming Yao.  (2026)  Fully aromatic fluorinated polyamide nanofiltration membranes formed at gas/liquid interfaces with ultrafast nonpolar organic solvent permeance.  JOURNAL OF MEMBRANE SCIENCE,      [PMID:] [10.1016/j.memsci.2026.125427]