The goal of chiral catalysis is to preferentially generate one enantiomer during a reaction. In modern organic synthesis, two common approaches are the metal–chiral ligand system and the small-molecule organocatalytic system. The 2001 Nobel Prize in Chemistry was awarded for asymmetric ...
In recent years, asymmetric organic catalytic processes have increasingly become more mature and have been utilized in practical application scenarios.In comparison to metal catalytic processes, organic amine catalysts present numerous potential advantages, such as a more stable physicochemical ...
Since the first proline-catalyzed asymmetric synthesis was reported in 1971, a number of asymmetric syntheses using proline and derivatives have been developed. Proline-type organocatalysts are predominantly applicable to a wide assortment of asymmetric aldol reactions and asymmetric ...
Asymmetric organocatalysis has emerged as a powerful synthetic tool that is complementary to metal-catalyzed reactions. Pioneering work in this area dates back to the 1970s in which Eder et al. and Hajos et al. separately reported an intramolecular asymmetric aldol reaction which employed ...
Aladdin offers the isothiourea organocatalyst homobenzotetramisole (HBTM) as part of our asymmetric catalysis portfolio in both (R, item number: B120975) and (S, item number: B120963) enantiomeric forms. These compounds have been widely used for enantioselective conversion and kinetic resolution ...
