Alcian blue 8GX - Dye-content ≥50% , CAS No.33864-99-2

CAS: 33864-99-2 Cat. No.: A105505 Molecular Weight: 1298.86 EC Number: 251-705-7 PubChem CID: 16211091

GRADE & PURITY Dye-content ≥50%

Synonyms

CI 74240 | Alcian Blue 8GX, powder | Alcian Blue 8GX, certified | HY-D0001 | Alcian Blue 8GX, for microscopy (Bact., Bot., Hist.) | Ingrain Blue 1 | AKOS015902443 | alcian-blue 8gx | Alcian Blue 8GX, BioReagent, suitable for detection of glycoproteins | A

Storage

Room temperature

Shipped In

Normal

Overview

Alcian Blue 8GX is used as a heteroglycan stain for neutral, sulfated and phosphated mucopolysaccharides and glycosaminoglycans in tissues such as cartilage and extracellular matrices.

application：

Alcian Blue 8GX is widely utilized as a heteroglycan stain for acidic, neutral, sulfated and phosphate polysaccharides and glycosaminoglycans in tissues. It finds application in both light and electron microscopy. It serves as an adhesive to stick glycol methacrylate sections to glass slides. Due to its large aromatic surface, it is used as a coating agent and modifies the property on the surfaces. It acts as a gelling agent for lubricating fluids and is also used in the modification of carbon paste electrode which promotes redox behavior and stability of electrode.

Specifications

Synonyms

CI 74240 | Alcian Blue 8GX, powder | Alcian Blue 8GX, certified | HY-D0001 | Alcian Blue 8GX, for microscopy (Bact., Bot., Hist.) | Ingrain Blue 1 | AKOS015902443 | alcian-blue 8gx | Alcian Blue 8GX, BioReagent, suitable for detection of glycoproteins | A

Specifications & Purity

Dye-content ≥50%

Biochemical and Physiological Mechanisms

Alcian Blue 8GX is used as a heteroglycan stain for neutral, sulfated and phosphated mucopolysaccharides and glycosaminoglycans in tissues such as cartilage and extracellular matrices

Storage

Room temperature

Shipped In

Normal

Names and Identifiers

• Pubchem Sid: 504768089
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504768089
• Canonical Smiles: CN(C)C(=[N+](C)C)SCC1=CC2=C(C=C1)C3=NC4=NC(=NC5=C6C=C(C=CC6=C([N-]5)N=C7C8=C(C=CC(=C8)CSC(=[N+](C)C)N(C)C)C(=N7)N=C2[N-]3)CSC(=[N+](C)C)N(C)C)C9=C4C=C(C=C9)CSC(=[N+](C)C)N(C)C.[Cl-].[Cl-].[Cl-].[Cl-].[Cu+2]
• IUPAC Name: copper;[dimethylamino-[[15,24,33-tris[[dimethylamino(dimethylazaniumylidene)methyl]sulfanylmethyl]-2,11,20,29,37,39-hexaza-38,40-diazanidanonacyclo[28.6.1.13,10.112,19.121,28.04,9.013,18.022,27.031,36]tetraconta-1(37),2,4(9),5,7,10,12(39),13(18),14,16,19,21,23,25,27,29,31(36),32,34-nonadecaen-6-yl]methylsulfanyl]methylidene]-dimethylazanium;tetrachloride
• InChIKey: CKLBXIYTBHXJEH-UHFFFAOYSA-J
• INCHI: 1S/C56H68N16S4.4ClH.Cu/c1-65(2)53(66(3)4)73-29-33-17-21-37-41(25-33)49-57-45(37)62-50-43-27-35(31-75-55(69(9)10)70(11)12)19-23-39(43)47(59-50)64-52-44-28-36(32-76-56(71(13)14)72(15)16)20-24-40(44)48(60-52)63-51-42-26-34(18-22-38(42)46(58-51)61-49)30-74-54(67(5)6)68(7)8;;;;;/h17-28H,29-32H2,1-16H3;4*1H;/q+2;;;;;+2/p-4
• Isomeric SMILES: CN(C)C(=[N+](C)C)SCC1=CC2=C(C=C1)C3=NC4=NC(=NC5=C6C=C(C=CC6=C([N-]5)N=C7C8=C(C=CC(=C8)CSC(=[N+](C)C)N(C)C)C(=N7)N=C2[N-]3)CSC(=[N+](C)C)N(C)C)C9=C4C=C(C=C9)CSC(=[N+](C)C)N(C)C.[Cl-].[Cl-].[Cl-].[Cl-].[Cu+2]
• WGK Germany: 3
• Alternate CAS: 75881-23-1
• PubChem CID: 16211091
• Molecular Weight: 1298.86

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Class Tetrapyrroles and derivatives
      • Subclass Phthalocyanines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Class: Tetrapyrroles and derivatives
• Subclass: Phthalocyanines
• Intermediate Tree Nodes: Not available
• Direct Parent: Phthalocyanines
• Alternative Parents: Isoindoles Benzenoids Pyrroles Heteroaromatic compounds Sulfenyl compounds Propargyl-type 1,3-dipolar organic compounds Organic metal halides Carboximidamides Azacyclic compounds Organic copper salts Organic chloride salts Hydrocarbon derivatives Organic cations
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Phthalocyanine skeleton - Isoindole - Isoindole or derivatives - Benzenoid - Pyrrole - Heteroaromatic compound - Organic metal halide - Carboximidamide - Sulfenyl compound - Azacycle - Propargyl-type 1,3-dipolar organic compound - Organic 1,3-dipolar compound - Organic transition metal salt - Organonitrogen compound - Organosulfur compound - Hydrocarbon derivative - Organic salt - Organic chloride salt - Organic nitrogen compound - Organic copper salt - Organic cation - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as phthalocyanines. These are cyclic tetrapyrroles that contain a phthalocyanine skeleton, which consists of four isoindole-type units, with the connecting carbon atoms in the macrocycle replaced by nitrogen.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Soluble in water, ethanol, ethylene glycol and 2-ethoxyethanol. Insoluble in xylene.
• Melt Point(°C): 148°C
• Molecular Weight: 1298.900 g/mol
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 12
• Rotatable Bond Count: 16
• Exact Mass: 1297.27 Da
• Monoisotopic Mass: 1295.27 Da
• Topological Polar Surface Area: 202.000 Ų
• Heavy Atom Count: 81
• Formal Charge: 0
• Complexity: 2270.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 6

XLogP3

References

1. Yue Yao, Hao Tang, Haiqiong Ma, Zidong Liu, Jinwen Huang, Xiufen Yang, Longyan Zhao, Qingxia Yuan.  (2023)  Chondroitin Sulfate/Dermatan Sulfate Hybrid Chains from Swim Bladder: Isolation, Structural Analysis, and Anticoagulant Activity.  Marine Drugs,  22  (1): (9).  [PMID:38276647] [10.3390/md22010009]

2. Xingyuan Wang, Xiansong Shi, Zhe Zhang, Congcong Yin, Zhipeng Zhang, Yong Wang.  (2023)  Ion-pairing design of covalent organic framework membranes for separation and controlled release of pharmaceuticals.  JOURNAL OF MEMBRANE SCIENCE,      [PMID:] [10.1016/j.memsci.2023.122347]

3. Zhaoyi He, Guiliang Li, Yang Liu, Ke Shi, Xiao Wang, Chuyang Y. Tang, Fu Liu.  (2023)  Lamellar crosslinking reinforced strategy to prepare 2D metal-organic framework membranes for ultra-fast and robust molecules/ions separation.  JOURNAL OF MEMBRANE SCIENCE,      [PMID:] [10.1016/j.memsci.2023.122352]

4. Xincheng Zhang, Fang Wang, Mi Ou, Haiyang Liu, Qing Luo, Shuzhan Fei, Jian Zhao, Kunci Chen, Qingshun Zhao, Kaibin Li.  (2023)  Effects of Myostatin b Knockout on Offspring Body Length and Skeleton in Yellow Catfish (Pelteobagrus fulvidraco).  Biology-Basel,  12  (10): (1331).  [PMID:37887041] [10.3390/biology12101331]

5. Jianbing Cui, Ruisheng Xu, Weifu Dong, Tatsuo Kaneko, Mingqing Chen, Dongjian Shi.  (2023)  Skin-Inspired Patterned Hydrogel with Strain-Stiffening Capability for Strain Sensors.  ACS Applied Materials & Interfaces,      [PMID:37812680] [10.1021/acsami.3c12127]

6. Zekun Li, Kun Jia, Xiaomei Chen, Jun Guo, Zhiguo Zheng, Weihua Chen, Yuan Peng, Yuhao Yang, Huiqiang Lu, Jian Yang.  (2023)  Exposure to Butylparaben Induces Craniofacial Bone Developmental Toxicity in Zebrafish (Danio rerio) Embryos.  ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,      [PMID:37776822] [10.1016/j.ecoenv.2023.115523]

7. Lin Duan, Haoyang Deng, Qianqing Zhang, Peijie Gao, Lang Wu.  (2023)  Environmentally relevant levels of BPA and NOR disturb early skeletal development in zebrafish.  COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY,      [PMID:37217109] [10.1016/j.cbpc.2023.109662]

8. Lulu Liu, Weilin Wu, Xiaogang Jin, Xiong Luo, Lili Wu.  (2023)  Interfacial Polymerization on Polyethersulfone Ultrafiltration Membrane to Prepare Nanofiltration Layers for Dye Separation.  Polymers,  15  (9): (2018).  [PMID:37177166] [10.3390/polym15092018]

9. Junyang Pan, Dan Hua, Yiping Hong, Xi Cheng, Fangsong Guo, Kok Bing Tan, Ziqi Zhong, Guowu Zhan.  (2023)  Design of hybrid g-C3N4/GO/MCE photocatalytic membranes with enhanced separation performance under visible-light irradiation.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2023.143164]

10. Yixin Yang, Guorong Li, Dan Ouyang, Zongwei Cai, Zian Lin.  (2022)  Dual-activation interfacial polymerization based anionic covalent organic framework nanofiltration membrane for high-flux dye separation.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2022.141008]

11. Shurui Han, Yingfang Xie, Qingping Xin, Jing Lv, Yanli Zhang, Fengkai Wang, Xiaojian Fu, Hong Li, Lizhi Zhao, Hui Ye, Yuzhong Zhang.  (2022)  High permeability dual-channel membranes based on porous Fluorine–Cerium nanosheets for molecular sieving.  JOURNAL OF MEMBRANE SCIENCE,      [PMID:] [10.1016/j.memsci.2022.121126]

12. Jianbing Cui, Jiwei Chen, Zhongbin Ni, Weifu Dong, Mingqing Chen, Dongjian Shi.  (2022)  High-Sensitivity Flexible Sensor Based on Biomimetic Strain-Stiffening Hydrogel.  ACS Applied Materials & Interfaces,      [PMID:36205693] [10.1021/acsami.2c15203]

13. Xinda You, Li Cao, Yawei Liu, Hong Wu, Runlai Li, Qianxiang Xiao, Jinqiu Yuan, Runnan Zhang, Chunyang Fan, Xiaoyao Wang, Pengfei Yang, Xiaoyu Yang, Yu Ma, Zhongyi Jiang.  (2022)  Charged Nanochannels in Covalent Organic Framework Membranes Enabling Efficient Ion Exclusion.  ACS Nano,      [PMID:35771947] [10.1021/acsnano.2c04767]

14. Zhenxiang Pan, Bizhen Zeng, Genying Yu, Jiaheng Teng, Hanmin Zhang, Liguo Shen, Lining Yang, Hongjun Lin.  (2022)  Mechanistic insights into Ca-alginate gel-associated membrane fouling affected by ethylene diamine tetraacetic acid (EDTA).  SCIENCE OF THE TOTAL ENVIRONMENT,      [PMID:35753486] [10.1016/j.scitotenv.2022.156912]

15. Zhenxiang Pan, Bizhen Zeng, Hongjun Lin, Jiaheng Teng, Hanmin Zhang, Huachang Hong, Meijia Zhang.  (2022)  Fundamental thermodynamic mechanisms of membrane fouling caused by transparent exopolymer particles (TEP) in water treatment.  SCIENCE OF THE TOTAL ENVIRONMENT,      [PMID:35066039] [10.1016/j.scitotenv.2022.153252]

16. Binjie Wang, Tianyi Chen, Anli Wang, Jiakai Fang, Jiye Wang, Weixuan Yao, Yuanzhao Wu.  (2021)  Anisodamine affects the pigmentation, mineral density, craniofacial area, and eye development in zebrafish embryos.  JOURNAL OF APPLIED TOXICOLOGY,  42  (6): (1067-1077).  [PMID:34967033] [10.1002/jat.4278]

17. Mei-Ling Liu, Lu Li, Ming-Jian Tang, Lan Hong, Shi-Peng Sun, Weihong Xing.  (2021)  Multi-component separation of small molecular/ionic pollutants with smart pH-gating membranes.  CHEMICAL ENGINEERING SCIENCE,      [PMID:] [10.1016/j.ces.2021.116854]

18. Yuefei Song, Yueke Sun, Nan Zhang, Chen Li, Mengxiang Hou, Kexin Chen, Tiemei Li.  (2021)  Custom-tailoring loose nanocomposite membrane incorporated bipiperidine/graphene quantum dots for high-efficient dye/salt fractionation in hairwork dyeing effluent.  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2021.118870]

19. Haixin Song, Tao Wu, Xiaotian Yang, Yangzheng Li, Ye Ye, Bo Li, Tao Liu, Shihui Liu, Jianhua Li.  (2021)  Surface Modification with NGF-Loaded Chitosan/Heparin Nanoparticles for Improving Biocompatibility of Cardiovascular Stent.  Stem Cells International,      [PMID:33986810] [10.1155/2021/9941143]

20. Mei-Ling Liu, Lu Li, Yu-Xuan Sun, Zheng-Jun Fu, Xue-Li Cao, Shi-Peng Sun.  (2020)  Scalable conductive polymer membranes for ultrafast organic pollutants removal.  JOURNAL OF MEMBRANE SCIENCE,      [PMID:] [10.1016/j.memsci.2020.118644]

21. Yongheng Yin, Huimin Liu, Hongbo Li, Sheng Li, Hanfang Liu, Chongbin Wang, Chengyun Gao.  (2020)  Efficient sol-gel synthesis of zwitterion functionalized titania for nanofiltration membrane with enhanced selectivity and antifouling performance.  Journal of the Taiwan Institute of Chemical Engineers,      [PMID:] [10.1016/j.jtice.2020.05.003]

22. Dan Ren, Yu-han Li, Shu-ping Ren, Tian-Yin Liu, Xiao-Lin Wang.  (2020)  Microporous polyarylate membrane with nitrogen-containing heterocycles to enhance separation performance for organic solvent nanofiltration.  JOURNAL OF MEMBRANE SCIENCE,      [PMID:] [10.1016/j.memsci.2020.118295]

23. Qianqian Yu, Xinda You, Hong Wu, Yanlei Su, Runnan Zhang, Yanan Liu, Chao Yang, Jianliang Shen, Jinqiu Yuan, Zhongyi Jiang.  (2020)  Ultrathin fluorinated self-cleaning membranes via coordination-driven metal-bridging assembly for water purification.  Journal of Materials Chemistry A,  8  (8): (4505-4514).  [PMID:] [10.1039/C9TA13957E]

24. Shu Xu, Dongwei Lu, Panpan Wang, Yumeng Zhao, Yan Sun, Jingyao Qi, Jun Ma.  (2020)  Polyphenol engineered membranes with dually charged sandwich structure for low-pressure molecular separation.  JOURNAL OF MEMBRANE SCIENCE,      [PMID:] [10.1016/j.memsci.2020.117885]

25. Jianliang Shen, Runnan Zhang, Yanlei Su, Benbing Shi, Xinda You, Weixiong Guo, Yu Ma, Jinqiu Yuan, Fei Wang, Zhongyi Jiang.  (2019)  Polydopamine-modulated covalent organic framework membranes for molecular separation.  Journal of Materials Chemistry A,  7  (30): (18063-18071).  [PMID:] [10.1039/C9TA05040J]

26. Fusheng Pan, Weixiong Guo, Yanlei Su, Niaz Ali Khan, Hao Yang, Zhongyi Jiang.  (2019)  Direct growth of covalent organic framework nanofiltration membranes on modified porous substrates for dyes separation.  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2019.01.064]

27. Yong Gao, Shu-Qi Deng, Xia Jin, Song-Liang Cai, Sheng-Run Zheng, Wei-Guang Zhang.  (2018)  The construction of amorphous metal-organic cage-based solid for rapid dye adsorption and time-dependent dye separation from water.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2018.09.124]

28. Xiao Wang, Xiaohui Ju, Tian-Zhi Jia, Qian-Cheng Xia, Jia-Lin Guo, Chen Wang, Zhaoliang Cui, Yong Wang, Weihong Xing, Shi-Peng Sun.  (2018)  New surface cross-linking method to fabricate positively charged nanofiltration membranes for dye removal.  JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY,  93  (8): (2281-2291).  [PMID:] [10.1002/jctb.5571]

29. Dongsheng Sun, Yang Liu, Huihui Wang, Fei Deng, Ying Zhang, Shan Zhao, Xiaojun Ma, Huijian Wu, Guangwei Sun.  (2017)  Novel decellularized liver matrix-alginate hybrid gel beads for the 3D culture of hepatocellular carcinoma cells.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:29157906] [10.1016/j.ijbiomac.2017.11.103]

30. Zhaowei Chen, Zhen Liu, Zhenhua Li, Enguo Ju, Nan Gao, Li Zhou, Jinsong Ren, Xiaogang Qu.  (2014)  Upconversion nanoprobes for efficiently in vitro imaging reactive oxygen species and in vivo diagnosing rheumatoid arthritis.  BIOMATERIALS,      [PMID:25477167] [10.1016/j.biomaterials.2014.10.066]

31. Jinjie Wang, Qian Lai, Hongyang Pan, Daming Sun, Chunfeng Yu, Wei Zhang, Jian Chen, Liqin Ma, Ling Li, Ren Zhou.  (2014)  Evaluation of specific marker CK13 and CK10/13 combined with APM staining for the diagnosis of amniotic fluid embolism and aspiration.  FORENSIC SCIENCE INTERNATIONAL,      [PMID:24705378] [10.1016/j.forsciint.2014.02.032]

32. Long Zhang, Jingzhen Wang, Ying Zhang, Linlin Zang, Yanqiu Yang, Yanhong Zhang, Xu Wang, Liguo Sun.  (2024)  Covalent triazine framework-based porous mixed matrix membranes for highly efficient dye/salt separation.  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2024.127745]

33. Pengfei Yang, Yanan Liu, Gowan-Hugh Whalley, Chengzhi Guo, Ya Li, A.Ozgur Yazaydin, Zhongyi Jiang, Marc-Olivier Coppens, Yang Lan.  (2024)  Cucurbit[6]uril-tuned nanochannels of graphene oxide membrane for enhanced water flux in nanofiltration.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2024.158137]

34. Zekun Zhou, Zezhen Zhang, Shuman Feng, Lulu Liu, Weishan Deng, Lili Wu.  (2024)  Effective separation of dyes/salts by sulfonated covalent organic framework membranes based on phenolamine network conditioning.  RSC Advances,  14  (21): (14593-14605).  [PMID:38708106] [10.1039/D4RA01736F]

35. Yuanzhao Wu, Ye'anlun Zhu, An Cheng, Weixuan Yao, Binjie Wang, Ruonan Zheng, Jiye Wang.  (2025)  Effects of tefluthrin exposure on early life stages in zebrafish: Insights into cardiac and skeletal development, oxidative stress and apoptosis.  ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,      [PMID:39978106] [10.1016/j.ecoenv.2025.117931]

36. Yisa Zhou, Ya Zhang, Jian Xue, Rui Wang, Jiale Dong, Zongjie Yin, Chen Guo, Haihui Wang.  (2024)  Electrochemically assisted preparation of graphitic carbon nitride nanosheet membranes for efficient water purification.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2024.151638]

37. Mengying Long, Luhui Yang, Niaz Ali Khan, Chao Yang, Guangwei He, Tao Wu, Dongmin An, Zhongyi Jiang.  (2025)  In-situ crystallization of covalent organic framework fillers in mixed matrix membranes via the reactive surface segregation approach.  Journal of Environmental Chemical Engineering,      [PMID:] [10.1016/j.jece.2025.116387]

38. Zhou Qu, Yanni Liu, Haoran Wang, Qianxi Yang, Hongwei Fan, Hong Meng.  (2025)  One-dimensional confinement-induced MOF-in-COF layer on polymeric substrate for helium separation.  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2025.132782]

39. Guiliang Li, Yang Liu, Zhaoyi He, Ke Shi, Fu Liu.  (2024)  Retrievable ultrafast covalent triazine framework membranes for organic solvent nanofiltration.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2024.149488]

40. Yawen Chang, Yu Liu, Fujuan Liu.  (2024)  Simple fabrication of breathable poly (vinylidene fluoride) fibrous membranes decorated by silica nanoparticles with enhanced waterproof property.  CERAMICS INTERNATIONAL,      [PMID:] [10.1016/j.ceramint.2024.10.225]

41. Weishan Deng, Zezhen Zhang, Lulu Liu, Zekun Zhou, Lili Wu.  (2024)  Tannin-assisted interfacial polymerization towards COF membranes for efficient dye separation.  RSC Advances,  14  (23): (16510-16519).  [PMID:38769964] [10.1039/D4RA02838D]

42. Menghao Lin, Juan Liu, Wenyu Zhou, Can Deng, Yaohan Du, Lichun Dong, Cailong Zhou.  (2025)  Mixed matrix membranes based on controllable synthesized one-dimensional HOFs for molecular separation.  JOURNAL OF MEMBRANE SCIENCE,      [PMID:] [10.1016/j.memsci.2025.124503]

43. Xianhua Zhang, Runfa Wu, Fasheng Liu, Min Huang, Xiaoyan Huang, Nannan Wang, Qianqian Huang, Minhong Zhang, Xinjun Liao, Huiqiang Lu, Lan Liao.  (2025)  The toxicity of guaiacol on craniofacial cartilage development through ROS-induced oxidative stress in zebrafish embryos.  ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,      [PMID:40749390] [10.1016/j.ecoenv.2025.118744]

44. Xiaoyu Tao, Yifei Gao, Zhengsen Jin, Shan Lu, Zhiqi Li, Siyu Guo, Qiqi Fan, Jiaqi Li, Chuanqi Qiao, Huiling Lei, Zhiqiang Zhang, Chongjun Zhao, Jiarui Wu.  (2025)  Co-administration of berberine and evodiamine: Mitigating evodiamine-induced hepatotoxicity and potentiating colitis treatment.  PHYTOMEDICINE,      [PMID:40865345] [10.1016/j.phymed.2025.157185]

45. Cheng-Ye Zhu, Jia-Hui Xin, Chao Zhang, Hao-Cheng Yang, Hong-Qing Liang, Zhi-Kang Xu.  (2025)  Designing polyurea membranes with twisted and durable skeleton for thermal/acid-stable efficient dye/salt separation.  JOURNAL OF MEMBRANE SCIENCE,      [PMID:] [10.1016/j.memsci.2025.124770]

46. Qi Zhu, Luwen Zhu, Jialu Lang, Jiawen Zhu, Di Chen, Yuanyan Huang, Jucong Zhang, Xiaochuan Wu, Jiahao Hu, Jiansong Ji, Qining Yang, Yongzhong Du.  (2025)  Dopamine-functionalized bioinspired pre-chondrogenic hydrogel for cell-free cartilage regeneration.  JOURNAL OF CONTROLLED RELEASE,      [PMID:41237861] [10.1016/j.jconrel.2025.114407]

47. Xinda You, Zifan Song, Youqing Tian, Ran Chen, Yuxiang Wu, Meijie Wang, Dai Shi, Shan Luo, Jiamei Sun, Yuanhui Xiao, Haixiong Liu, Hanyang Liu, Beili Lu, Lirong Tang, Xingzhong Cao, Jiande Lin, Biao Huang.  (2025)  Coordination-reconstructed cellulose membranes for precise molecular separation.  JOURNAL OF MEMBRANE SCIENCE,      [PMID:] [10.1016/j.memsci.2025.125020]

48. Jiajie Shi, Yang Liu, Yongsheng Chen, Zhenggong Wang, Jian Jin.  (2026)  Fluorinated Covalent Organic Framework Membranes for High-Flux Nonpolar Organic Solvent Nanofiltration.  ADVANCED FUNCTIONAL MATERIALS,      [PMID:] [10.1002/adfm.202523813]

49. Tianyi Chen, Fengjun Fan, An Cheng, Yumei Xia, Haoze Chen, Jiakai Fang, Yangyu Chen, Tianjia Li, Anli Wang, Binjie Wang, Weixuan Yao, Yuanzhao Wu.  (2026)  Flocoumafen exposure induces skeletal developmental toxicity and neurotoxicity in zebrafish (Danio rerio).  TOXICOLOGY LETTERS,      [PMID:41643754] [10.1016/j.toxlet.2026.111852]

50. Lingya Fei, Xiaoting Ye, Jingyu Yu, Baoliang Chen, Xiaoying Zhu.  (2026)  Structural perfection through imperfection: Defect-engineered MOF-GO composite membrane for high-performance water purification.  JOURNAL OF MEMBRANE SCIENCE,      [PMID:] [10.1016/j.memsci.2026.125404]

51. Yan Wang, Xin Yang, Chen-Xuan Li, Wenhui Xu, Hong Mei, Feng Zhang, Zhuoya Gao, Yelei Liu, Kai Zhou, Houyun Yang, Kangping Cui.  (2026)  Singlet oxygen-dominated peroxymonosulfate activation by wastewater-borne copper phthalocyanine for simultaneous dye degradation and pigment recovery.  JOURNAL OF ENVIRONMENTAL MANAGEMENT,      [PMID:] [10.1016/j.jenvman.2026.129738]