Chemerin-9 (149-157) TFA, Agonist of chemerin receptor 1;Agonist of chemerin receptor 2, CAS No.676367-27-4(free base), Agonist of chemerin receptor 1;Agonist of chemerin receptor 2

CAS: 676367-27-4(free base) Cat. No.: C287731 Molecular Weight: 1063.16(free base)

GRADE & PURITY Moligand™, ≥95%

Overview

Chemerin-9 (149-157) TFA is a potent agonist of chemokine-like receptor 1 (CMKLR1) . Chemerin-9 (149-157) TFA has anti-inflammatory activity. Chemerin-9 (149-157) TFA stimulates phosphorylation of Akt and ERK as well as ROS production. Chemerin-9 (149-157) TFA ameliorates Aβ1-42-induced memory impairmen. Chemerin-9 (149-157) TFA regulates immune responses, adipocyte differentiation, and glucose metabolism.

Specifications

Product Name

Chemerin-9 (149-157) TFA, Agonist of chemerin receptor 1;Agonist of chemerin receptor 2, CAS No.676367-27-4(free base)

Synonyms

Chemerin-9, Human TFA

Grade

Moligand™

Specifications & Purity

Moligand™, ≥95%

Biochemical and Physiological Mechanisms

Potent chemokine-like receptor 1 (CMKLR1; also known as chemerin receptor 23, ChemR23) agonist (EC50= 7.1 nM at CMKLR expressed in CHO cells). Corresponds to C-terminal of full length human Chemerin, amino acids 149 - 157. Activates Gi/osignaling pathways

Sequence

YFPGQFAFS

Action Type

AGONIST

Mechanism of action

Agonist of chemerin receptor 1;Agonist of chemerin receptor 2

CAS

676367-27-4(free base)

Molecule Type

Peptide

Storage and Shipping

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Associated Targets(Human)

GPR1 Tchem G-protein coupled receptor 1 (0 Activities)

Discover Target: GPR1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CMKLR1 Tchem Chemokine-like receptor 1 (0 Activities)

Discover Target: CMKLR1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Genetic information

• Alternate Names: Chemerin-9, Human TFA
• Reference:
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