N-Fmoc-L-valine N-succinimidyl ester - ≥97% , CAS No.130878-68-1

CAS: 130878-68-1 Cat. No.: F100759 Molecular Weight: 436.5

GRADE & PURITY ≥97%

Synonyms

Fmoc-Val-OSu | N-Fmoc-L-valine N-succinimidyl ester | N-Fmoc-L-valine N-hydroxysuccinimide ester | n-((9h-fluoren-9-ylmethoxy)carbonyl)-l-valine 2,5-dioxo-1-pyrrolidinyl ester | ((1s)-1-(((2,5-dioxo-1-pyrrolidinyl)oxy)carbonyl)-2-methylpropyl) 9h-fluoren-

Storage

Store at 2-8°C

Shipped In

Wet ice

Overview

Fmoc-L-Val-OSu is an Fmoc protected valine derivative that is potentially useful for proteomics studies and solid phase peptide synthesis techniques. Valine is one of the simplest amino acids - an isopropyl group as the side chain. This smaller side chain confers a fairly high degree of flexibility when incorporated into a polypeptide chain. The Fmoc group is typically removed with a base such as pyridine - an orthogonal de-protection strategy to the acid labilie Boc group.
An Fmoc protected valine derivative.

Specifications

Synonyms

Fmoc-Val-OSu | N-Fmoc-L-valine N-succinimidyl ester | N-Fmoc-L-valine N-hydroxysuccinimide ester | n-((9h-fluoren-9-ylmethoxy)carbonyl)-l-valine 2, 5-dioxo-1-pyrrolidinyl ester | ((1s)-1-(((2, 5-dioxo-1-pyrrolidinyl)oxy)carbonyl)-2-methylpropyl) 9h-fluoren-

Specifications & Purity

≥97%

Storage

Store at 2-8°C

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥97%

Names and Identifiers

• Pubchem Sid: 504766313
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504766313
• Canonical Smiles: CC(C)C(C(=O)ON1C(=O)CCC1=O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24
• IUPAC Name: (2,5-dioxopyrrolidin-1-yl) (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-methylbutanoate
• InChIKey: JPJMNCROLRPFHI-QFIPXVFZSA-N
• INCHI: 1S/C24H24N2O6/c1-14(2)22(23(29)32-26-20(27)11-12-21(26)28)25-24(30)31-13-19-17-9-5-3-7-15(17)16-8-4-6-10-18(16)19/h3-10,14,19,22H,11-13H2,1-2H3,(H,25,30)/t22-/m0/s1
• Isomeric SMILES: CC(C)[C@@H](C(=O)ON1C(=O)CCC1=O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24
• Molecular Weight: 436.5
• Reaxy-Rn: 33035623
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=33035623&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Class Fluorenes

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Class: Fluorenes
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Fluorenes
• Alternative Parents: Valine and derivatives Pyrrolidine-2-ones Dicarboximides Carbamate esters Lactams Monocarboxylic acids and derivatives Azacyclic compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Fluorene - Valine or derivatives - Alpha-amino acid or derivatives - Pyrrolidone - 2-pyrrolidone - Dicarboximide - Pyrrolidine - Carbamic acid ester - Lactam - Monocarboxylic acid or derivatives - Carboxylic acid derivative - Organoheterocyclic compound - Azacycle - Hydrocarbon derivative - Organic oxide - Organooxygen compound - Organonitrogen compound - Organic oxygen compound - Organic nitrogen compound - Carbonyl group - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as fluorenes. These are compounds containing a fluorene moiety, which consists of two benzene rings connected through either a cyclopentane, cyclopentene, or cyclopenta-1,3-diene.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Slightly soluble in water.
• Molecular Weight: 436.500 g/mol
• XLogP3: 3.500
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 8
• Exact Mass: 436.163 Da
• Monoisotopic Mass: 436.163 Da
• Topological Polar Surface Area: 102.000 Ų
• Heavy Atom Count: 32
• Formal Charge: 0
• Complexity: 715.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1