NIR AIE780COOH Fluorescent Nanoparticles (50 nm, AIE) - BioReagent, ≥1.5 mg/mL

Cat. No.: N1456449

GRADE & PURITY BioReagent, ≥1.5 mg/mL

Storage

Store at 2-8°C,Protected from light

Shipped In

Wet ice

Application

In Vivo Imaging

Overview

  This series of fluorescent nanoparticles are obtained by coating aggregation-induced emission (AIE) molecules with DSPE-PEG₂₀₀₀. The AIE molecules are embedded inside the nanoparticles. Due to the characteristics of aggregation-induced emission, there is no fluorescence quenching effect during aggregation, which can greatly improve the fluorescence efficiency of AIE molecules.
  This series of nanoparticles have good monodispersity and uniform particle size. After the AIE molecules are wrapped by DSPE-PEG₂₀₀₀, the influence of the external environment on them is isolated, and the fluorescence stability is greatly improved, with a lasting stability fluorescence effect.
  This series of nanoparticles are near-infrared fluorescent nanoparticles, suitable for in vivo imaging of small animals, and have the characteristics of strong tissue penetration, good water solubility, and low biological toxicity. At the same time, we can provide microspheres with different particle sizes and functional groups, which can meet the diverse needs of customers.

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Product Specifications and Parameters

Product Name	NIR AIE780 Fluorescent Nanoparticles	NIR AIE780 Fluorescent Nanoparticles	NIR AIE780COOH Fluorescent Nanoparticles	NIR AIE780COOH Fluorescent Nanoparticles
Item Number	N1456443	N1456447	N1456448	N1456449
Particle Size (nm)	90 ± 10	50 ± 10	90 ± 10	50 ± 10
Concentration (mg/ml)	≥2.0mg/ml	≥1.5mg/ml	≥2.0mg/ml	≥1.5mg/ml
Luminescence Color	Near - Infrared	Near - Infrared	Near - Infrared	Near - Infrared
Maximum Excitation Wavelength (nm)	620 ± 15	620 ± 15	620 ± 15	620 ± 15
Maximum Emission Wavelength (nm)	780± 15	780± 15	780± 15	780± 15
Modified Group	None	None	Carboxyl	Carboxyl
Specification	50μl，100μl，500μl	50μl，100μl，500μl	50μl，100μl，500μl	50μl，100μl，500μl
Preservation Solution Component	Ultrapure Water	Ultrapure Water	Ultrapure Water	Ultrapure Water
Storage Conditions	2 - 8°C, store in the dark	2 - 8°C, store in the dark	2 - 8°C, store in the dark	2 - 8°C, store in the dark

Product Imaging Steps
The steps are as follows:
  Experimental Preparation: Prepare 5 - week - old male Balb/c nude mice, and inject the tumor cell line (1×10⁶/0.1ml) subcutaneously into male Balb/c nude mice or into sites such as the tail vein.
  When the tumor volume grows to 60 - 80mm³, perform imaging on the nude mice as a control.
  Animal Imaging Experiment: Inject 0.2ml (1mg/ml AIE NPs) of near - infrared fluorescent microspheres into the nude mice via the tail vein, and then perform imaging on the nude mice.
Product Application Scenarios
Example: Brain Angiography in Mice

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  This protocol is for reference only. Researchers should optimize the specific experimental conditions according to their own projects.

Specifications

Specifications & Purity

BioReagent, ≥1.5 mg/mL

Stability And Storage

Store at 2-8℃ for 6 months. Upon receipt, it is recommended to aliquot. Store in the dark.

Storage

Store at 2-8°C, Protected from light

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

BioReagent