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· · COA & SDS available for every product · Same-day shipping on in-stock items PPQ 102 - ≥98%(HPLC) , CAS No.931706-15-9
Synonyms
7,9-dimethyl-6-(5-methylfuran-2-yl)-11-phenyl-5,6-dihydropyrimido[4',5':3,4]pyrrolo[1,2-a]quinoxaline-8,10(7H,9H)-dione | PPQ-102 | CFTR Inhibitor IV | 6,7-Dihydro-7,9-dimethyl-6-(5-methyl-2-furanyl)-11-phenylpyrimido[4',5':3,4]pyrrolo[1,2-a]quinoxaline-8
Shipped In
Ice chest + Ice pads
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Why this grade ≥98%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Synonyms
7, 9-dimethyl-6-(5-methylfuran-2-yl)-11-phenyl-5, 6-dihydropyrimido[4', 5':3, 4]pyrrolo[1, 2-a]quinoxaline-8, 10(7H, 9H)-dione | PPQ-102 | CFTR Inhibitor IV | 6, 7-Dihydro-7, 9-dimethyl-6-(5-methyl-2-furanyl)-11-phenylpyrimido[4', 5':3, 4]pyrrolo[1, 2-a]quinoxaline-8
Specifications & Purity
≥98%(HPLC)
Biochemical and Physiological Mechanisms
Potent, voltage-independent CFTR chloride channel inhibitor (IC50= 90 nM). Reduces the size and number of renal cysts in an embryonic kidney culture model of polycystic kidney disease. Also increases VEGF-A production from airway epithelial cellsin vitro.
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Names and Identifiers Pubchem Sid 504768007 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504768007 Canonical Smiles CC1=CC=C(O1)C2C3=C4C(=C(N3C5=CC=CC=C5N2)C6=CC=CC=C6)C(=O)N(C(=O)N4C)C IUPAC Name 12,14-dimethyl-9-(5-methylfuran-2-yl)-17-phenyl-1,8,12,14-tetrazatetracyclo[8.7.0.02,7.011,16]heptadeca-2,4,6,10,16-pentaene-13,15-dione InChIKey MNOOVRNGPIWJDI-UHFFFAOYSA-N INCHI 1S/C26H22N4O3/c1-15-13-14-19(33-15)21-24-23-20(25(31)29(3)26(32)28(23)2)22(16-9-5-4-6-10-16)30(24)18-12-8-7-11-17(18)27-21/h4-14,21,27H,1-3H3 Isomeric SMILES CC1=CC=C(O1)C2C3=C4C(=C(N3C5=CC=CC=C5N2)C6=CC=CC=C6)C(=O)N(C(=O)N4C)C PubChem CID 16016583 Molecular Weight 438.48
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Class Pyrroles Subclass Substituted pyrroles Intermediate Tree Nodes Not available Direct Parent Phenylpyrroles Alternative Parents Quinoxalines Secondary alkylarylamines Pyrimidones Aralkylamines Benzene and substituted derivatives Vinylogous amides Heteroaromatic compounds Furans Ureas Lactams Oxacyclic compounds Azacyclic compounds Organooxygen compounds Organic oxides Hydrocarbon derivatives Molecular Framework Aromatic heteropolycyclic compounds Substituents 2-phenylpyrrole - Quinoxaline - Pyrimidone - Aralkylamine - Secondary aliphatic/aromatic amine - Monocyclic benzene moiety - Pyrimidine - Benzenoid - Furan - Heteroaromatic compound - Vinylogous amide - Lactam - Urea - Oxacycle - Azacycle - Secondary amine - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Organic oxide - Organic oxygen compound - Amine - Organic nitrogen compound - Aromatic heteropolycyclic compound Description This compound belongs to the class of organic compounds known as phenylpyrroles. These are polycyclic aromatic compounds containing a benzene ring linked to a pyrrole ring through a CC or CN bond. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 8.77, Max Conc. mM: 20 with gentle warming Molecular Weight 438.500 g/mol XLogP3 3.700 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 4 Rotatable Bond Count 2 Exact Mass 438.169 Da Monoisotopic Mass 438.169 Da Topological Polar Surface Area 70.700 Ų Heavy Atom Count 33 Formal Charge 0 Complexity 785.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 1 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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