Indole-3-carboxaldehyde - Moligand™, 10 mM in DMSO , CAS No.487-89-8

CAS: 487-89-8 Cat. No.: I1500225 Molecular Weight: 145.16 Beilstein Registry Number: 21313 EC Number: 207-665-8
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GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
Storage
Argon charged,Store at -80°C
Shipped In
Dry ice packs + Cold packs
Size
Status
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Qty
1ml
I1500225-1ml
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$58.90
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Why this grade

Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Argon charged,Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 20 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Indole-3-carboxaldehyde (3-Formylindole), a banlangen extract, is the product of the oxidative degradation of indole-3-acetic acid (IAA) by crude enzyme preparations from etiolated pea seedlings. Indole-3-carboxaldehyde is a biochemical used to prepare analogs of the indole phytoalexin cyclobrassinin. Indole-3-carboxaldehyde also enhances the epithelial barrier and anti-inflammatory activity in the intestinal tract .

Specifications

Specifications & Purity
Moligand™, 10 mM in DMSO
Storage
Argon charged, Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Names and Identifiers
Isomeric SMILES C1=CC=C2C(=C1)C(=CN2)C=O
WGK Germany 3
RTECS NL5993600
Molecular Weight 145.16
Beilstein 21313
Reaxy-Rn 114117
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=114117&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
Flash Point(°C)240℃
Melt Point(°C)193-198°C
Documents & Articles
Citations of This Product
References
1. Yue Zhu, Yuting Ai, Jianfu Zhou, Xiaozhuan Jia, Shuying Liu, Bo Zhu, Yimin Qin, Jianping Jiang, Zhenzhong Yang.  (2025)  Unveiling bioactive components in Sargassum fusiforme via phytochemical and biological evaluation: A heterogeneous information ensemble approach.  Chinese Herbal Medicines,      [PMID:41399786] [10.1016/j.chmed.2025.08.002]
2. Haiyan Zhao, Hongfu He, Zhongjie Shen, Chunle Wei, Limin Yin, Yunying Zhu, Hongxia Lu, Runjiang Song, Deyu Hu.  (2023)  Development and Mechanism Investigation of Novel Thioacetalized Indoles as Antiphytoviral Agents.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:37937740] [10.1021/acs.jafc.3c03967]
3. Lingling Ma, Lv Li, Minghao Yuan, Lei Bai, Anran Zhang, Xiaoming Yan, Gaohong He, Fengxiang Zhang.  (2022)  Hydrophilic–Hydrophobic Bulky Units Modified Anion Exchange Membranes for Fuel Cell Application.  ACS Sustainable Chemistry & Engineering,      [PMID:] [10.1021/acssuschemeng.1c07886]
4. Xiang He, Ruyue Liu, Huiqing Liu, Ruixiao Wang, Zhenhao Xi, Yixiang Lin, Jie Wang.  (2021)  Facile Preparation of Tunicate-Inspired Chitosan Hydrogel Adhesive with Self-Healing and Antibacterial Properties.  Polymers,  13  (24): (4322).  [PMID:34960874] [10.3390/polym13244322]
5. Jia Yin, Yujie Song, Yaozhong Hu, Yuanyifei Wang, Bowei Zhang, Jin Wang, Xuemeng Ji, Shuo Wang.  (2021)  Dose-Dependent Beneficial Effects of Tryptophan and Its Derived Metabolites on Akkermansia In Vitro: A Preliminary Prospective Study.  Microorganisms,  (7): (1511).  [PMID:34361945] [10.3390/microorganisms9071511]
6. Xiaona Zhang, Liang Sun, Wei Zheng, Xichang Bao, Ning Wang, Ting Wang, Renqiang Yang.  (2013)  The preparation and properties of bulk-heterojunction organic solar cells with indole-containing fulleropyrrolidine derivatives as acceptors.  TETRAHEDRON,      [PMID:] [10.1016/j.tet.2013.09.046]
7. Yewei Xu, Haoran Zhu, Shijie Mo, Yangqing Mao, Chi Zhong, Ying Huang, Rui Yuan, Min Zheng, Mingru Zhou, Guanjun Chang.  (2024)  Adsorption of 2,4,6-trinitrotoluene by indole-based porous organic polymer with suitable three-dimensional space size via physisorption and chemisorption.  POLYMER,      [PMID:] [10.1016/j.polymer.2024.126993]
8. Han Ziyi, Fu Jian, Gong Aiyan, Ren Wenkai.  (2025)  Bacterial indole-3-propionic acid inhibits macrophage IL-1β production through targeting methionine metabolism.  Science China-Life Sciences,      [PMID:39825207] [10.1007/s11427-024-2789-1]
9. Zhang Junzhi, Lin Binyan, Zhang Ying, Hu Xiaochao, Liu Tongtong, Liu E-Hu, Liu Shijia.  (2024)  Baitouweng decoction alleviates ulcerative colitis by regulating tryptophan metabolism through DOPA decarboxylase promotion.  Frontiers in Pharmacology,      [PMID:38974042] [10.3389/fphar.2024.1423307]
10. Susu Zhao, Lixin Sun, Yibo Liu, Chuanhui Gao, Li Ding, Ze Kan, Yuetao Liu.  (2025)  Cation-indole supramolecular interaction constructed novel silicone anti-fouling materials.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.159423]
11. Mengshi Xiao, Jiayuan Bi, Xinmiao Ren, Xiaodan Fu, Dongyu Li, Rong Li, Haijin Mou.  (2024)  Evaluation of potential prebiotic activity of a novel fucose-containing trisaccharide prepared from bacterial exopolysaccharides.  Food Bioscience,      [PMID:] [10.1016/j.fbio.2024.104380]
12. Jia Cheng Qian, Heng Peng Zhang, Yi Wang, Dan Liu.  (2024)  Heating conversion of indole-3-carbinol into N-substituted oligomers with anti-melanoma effect.  Food Chemistry-X,      [PMID:38707780] [10.1016/j.fochx.2024.101410]
13. Yufei Deng, Xiaoying Hou, Qian Fang, Haiping Wang, Xiaoxuan Li, Zhiyong Hu, Zhaolu Liu, Limei Fan, Yunyi Liu, Zhengqi Fu, Xiji Shu, Binlian Sun, Lijun Huang, Yuchen Liu.  (2025)  High-salt diet decreases FOLFOX efficacy via gut bacterial tryptophan metabolism in colorectal cancer.  MOLECULAR MEDICINE,      [PMID:39972411] [10.1186/s10020-025-01122-8]
14. Yvhao Xie, Xinxin Li, Qingshi Meng, Jinjun Li, Xin Wang, Liying Zhu, Weiwei Wang, Xiaoqiong Li.  (2024)  Interplay between gut microbiota and tryptophan metabolism in type 2 diabetic mice treated with metformin.  Microbiology Spectrum,      [PMID:39162538] [10.1128/spectrum.00291-24]
15. Yating Xu, Li Ning, Yu Si, Xiu Li, Ruyue Wang, Qingling Ren.  (2025)  Metformin-mediated intestinal AMPK activation ameliorates PCOS through gut microbiota modulation and metabolic pathways.  Frontiers in Endocrinology,      [PMID:40041289] [10.3389/fendo.2025.1526109]
16. Xiaomeng Chu, Zeqiang Liu, He Gao, Kang Geng, Shaojie Liu, Xuteng Xing, Erjun Tang, Nanwen Li, Song Zhao.  (2024)  Promising candidates of ether-free backbone comb-shaped sulfonated poly(oxindole biphenylene) membranes for enhanced electrochemical hydrogen compression performance.  JOURNAL OF MEMBRANE SCIENCE,      [PMID:] [10.1016/j.memsci.2024.122626]
17. Yongqi Tian, Yuanyuan Chen, Ruyang Huang, Tao Wang, Shaoyun Wang.  (2025)  Synergistic inhibition of Pseudomonas aeruginosa by EGCG and I3A: preliminary mechanisms and application in fish meat preservation.  INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY,      [PMID:40239291] [10.1016/j.ijfoodmicro.2025.111193]
18. Lei Zhang, Yi Wang, Yan Guo, Xi-Yuan Feng, Xiu-Li Wang, Lin Chen, Yu-Zhong Wang.  (2025)  Smart Crosslinkable Aromatic-Imine Enables Integrated Heat-Resistance, Flame Retardancy, Smoke Suppression and Non-Dripping for Polyester.  POLYMER DEGRADATION AND STABILITY,      [PMID:] [10.1016/j.polymdegradstab.2025.111747]
19. Xin Li, Jiaxian Li, Shiming jia, Guoying Wang.  (2025)  High-efficiency in situ detection of atmospheric isoprene peroxyl radicals by furan-based fluorescent probe.  ATMOSPHERIC ENVIRONMENT,      [PMID:] [10.1016/j.atmosenv.2025.121739]
20. Yang Shuai, Song Jiawei, Wang Zhenzhen, Peng Guang, Tong Linglin, Li Xin, Yang Kexin, Chen Yang, Zhang He, Zhang Qing, Chen Renjin.  (2026)  eIF6 deficiency alleviates colorectal cancer by modulating the gut microbiota and related metabolites.  CELL DEATH AND DIFFERENTIATION,      [PMID:41620567] [10.1038/s41418-026-01674-0]
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