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Glucokinase (GCK)

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  1. AM 2394
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    AM 2394
    CAS: 1442684-77-6 Formula: C22H25N5O4 Molecular Weight: 423.47
    ≥98%(HPLC)
    In Stock Item #: A288847
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    Technical Identifiers
    IUPAC Name
    1-[5-[6-(2-hydroxy-2-methylpropoxy)pyridin-3-yl]-4-(5-methylpyridin-3-yl)oxypyridin-2-yl]-3-methylurea
    SMILES
    CC1=CC(=CN=C1)OC2=CC(=NC=C2C3=CN=C(C=C3)OCC(C)(C)O)NC(=O)NC
    InChIKey
    QUISANLDBDCMPD-UHFFFAOYSA-N
    InChI
    1S/C22H25N5O4/c1-14-7-16(11-24-9-14)31-18-8-19(27-21(28)23-4)25-12-17(18)15-5-6-20(26-10-15)30-13-22(2,3)29/h5-12,29H,13H2,1-4H3,(H2,23,25,27,28)
    Synonyms
    N-[6'-(2-Hydroxy-2-methylpropoxy)-4-[(5-methyl-3-pyridinyl)oxy][3,3'-bipyridin]-6-yl]-N'-methylurea | AM-2394 | AM2394
  2. AGI-5198, Inhibitor of isocitrate dehydrogenase (NADP(+)) 1
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    AGI-5198, Inhibitor of isocitrate dehydrogenase (NADP(+)) 1
    CAS: 1355326-35-0 EC Number: 806-071-1 Formula: C27H31FN4O2 Molecular Weight: 462.56
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: A126546
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    IUPAC Name
    N-cyclohexyl-2-(3-fluoro-N-[2-(2-methylimidazol-1-yl)acetyl]anilino)-2-(2-methylphenyl)acetamide
    SMILES
    CC1=CC=CC=C1C(C(=O)NC2CCCCC2)N(C3=CC(=CC=C3)F)C(=O)CN4C=CN=C4C
    InChIKey
    FNYGWXSATBUBER-UHFFFAOYSA-N
    InChI
    1S/C27H31FN4O2/c1-19-9-6-7-14-24(19)26(27(34)30-22-11-4-3-5-12-22)32(23-13-8-10-21(28)17-23)25(33)18-31-16-15-29-20(31)2/h6-10,13-17,22,26H,3-5,11-12,show more
    Synonyms
    HMS3653K15 | N-cyclohexyl-2-(N-(3-fluorophenyl)-2-(2-methyl-1H-imidazol-1-yl)acetamido)-2-o-tolylacetamide | AKOS0266...
  3. AGI-5198, Inhibitor of isocitrate dehydrogenase (NADP(+)) 1
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    AGI-5198, Inhibitor of isocitrate dehydrogenase (NADP(+)) 1
    CAS: 1355326-35-0 EC Number: 806-071-1 Formula: C27H31FN4O2 Molecular Weight: 462.56
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: A421351
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    Technical Identifiers
    IUPAC Name
    N-cyclohexyl-2-(3-fluoro-N-[2-(2-methylimidazol-1-yl)acetyl]anilino)-2-(2-methylphenyl)acetamide
    SMILES
    CC1=CC=CC=C1C(C(=O)NC2CCCCC2)N(C3=CC(=CC=C3)F)C(=O)CN4C=CN=C4C
    InChIKey
    FNYGWXSATBUBER-UHFFFAOYSA-N
    InChI
    1S/C27H31FN4O2/c1-19-9-6-7-14-24(19)26(27(34)30-22-11-4-3-5-12-22)32(23-13-8-10-21(28)17-23)25(33)18-31-16-15-29-20(31)2/h6-10,13-17,22,26H,3-5,11-12,show more
    Synonyms
    HMS3653K15 | N-cyclohexyl-2-(N-(3-fluorophenyl)-2-(2-methyl-1H-imidazol-1-yl)acetamido)-2-o-tolylacetamide | AKOS0266...
  4. GKA 50
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    GKA 50
    CAS: 851884-87-2 EC Number: 804-711-4 PubChem CID: 11340230 Formula: C26H28N2O6 Molecular Weight: 464.51
    ≥98%(HPLC)
    Out of Stock Item #: G287266
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    IUPAC Name
    6-[[3-[(2S)-1-methoxypropan-2-yl]oxy-5-[(2S)-1-phenylpropan-2-yl]oxybenzoyl]amino]pyridine-3-carboxylic acid
    SMILES
    CC(CC1=CC=CC=C1)OC2=CC(=CC(=C2)C(=O)NC3=NC=C(C=C3)C(=O)O)OC(C)COC
    InChIKey
    OCBMECSFDVUYQN-ROUUACIJSA-N
    InChI
    1S/C26H28N2O6/c1-17(11-19-7-5-4-6-8-19)33-22-12-21(13-23(14-22)34-18(2)16-32-3)25(29)28-24-10-9-20(15-27-24)26(30)31/h4-10,12-15,17-18H,11,16H2,1-3H3,show more
    Synonyms
    GKA 50;GKA50 | 6-((3-((1S)-2-Methoxy-1-methylethoxy)-5-((1S)-1-methyl-2-phenylethoxy)benzoyl)amino)-3-pyridinecarboxy...
  5. WAY-621924
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    WAY-621924
    CAS: 745789-70-2 PubChem CID: 2092675 Formula: C17H14N2O2S Molecular Weight: 310.37
    10mM in DMSO
    In Stock Item #: W425804
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    Technical Identifiers
    IUPAC Name
    N-(4-methyl-1,3-thiazol-2-yl)-3-phenoxybenzamide
    SMILES
    CC1=CSC(=N1)NC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3
    InChIKey
    KZKCURLGSBGETL-UHFFFAOYSA-N
    InChI
    1S/C17H14N2O2S/c1-12-11-22-17(18-12)19-16(20)13-6-5-9-15(10-13)21-14-7-3-2-4-8-14/h2-11H,1H3,(H,18,19,20)
  6. WAY-621924
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    WAY-621924
    CAS: 745789-70-2 PubChem CID: 2092675 Formula: C17H14N2O2S Molecular Weight: 310.37
    ≥98%
    In Stock Item #: W417723
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    Technical Identifiers
    IUPAC Name
    N-(4-methyl-1,3-thiazol-2-yl)-3-phenoxybenzamide
    SMILES
    CC1=CSC(=N1)NC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3
    InChIKey
    KZKCURLGSBGETL-UHFFFAOYSA-N
    InChI
    1S/C17H14N2O2S/c1-12-11-22-17(18-12)19-16(20)13-6-5-9-15(10-13)21-14-7-3-2-4-8-14/h2-11H,1H3,(H,18,19,20)
    Synonyms
    N-(4-Methyl-1,3-thiazol-2-yl)-3-phenoxybenzamide
  7. no_selection
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    AZD1656, Hexokinase type IV activator
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: A607857
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    IUPAC Name
    3-[5-(azetidine-1-carbonyl)pyrazin-2-yl]oxy-5-[(2S)-1-methoxypropan-2-yl]oxy-N-(5-methylpyrazin-2-yl)benzamide
    SMILES
    COC[C@@H](Oc1cc(Oc2ncc(nc2)C(=O)N2CCC2)cc(c1)C(=O)Nc1ncc(nc1)C)C
    InChIKey
    FJEJHJINOKKDCW-INIZCTEOSA-N
    InChI
    1S/C24H26N6O5/c1-15-10-27-21(12-25-15)29-23(31)17-7-18(34-16(2)14-33-3)9-19(8-17)35-22-13-26-20(11-28-22)24(32)30-5-4-6-30/h7-13,16H,4-6,14H2,1-3H3,(Hshow more
    Synonyms
    (S)-3-(5-(Azetidine-1-carbonyl)pyrazin-2-yloxy)-5-(1-methoxypropan-2-yloxy)-N-(5-methylpyrazin-2-yl)benzamide | BA171...
  8. no_selection
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    BMS-820132, Activator of Glucokinase
    CAS: 1001419-18-6 Formula: C26H33N6O7P Molecular Weight: 572.55
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: B608139
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    Technical Identifiers
    Synonyms
    BMS820132;compound 31
  9. AZD1656 - 10mM in DMSO CAS No(919783-22-5) by Aladdin Scientific
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    AZD1656
    CAS: 919783-22-5 EC Number: 680-412-0 PubChem CID: 16039797 Formula: C24H26N6O5 Molecular Weight: 478.50
    Liquid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    Out of Stock Item #: A655241
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  11. AZD1656 - ≥98% CAS No(919783-22-5) by Aladdin Scientific
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    AZD1656
    CAS: 919783-22-5 EC Number: 680-412-0 PubChem CID: 16039797 Formula: C24H26N6O5 Molecular Weight: 478.50
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    Out of Stock Item #: A647970
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    Technical Identifiers
    IUPAC Name
    3-[5-(azetidine-1-carbonyl)pyrazin-2-yl]oxy-5-[(2S)-1-methoxypropan-2-yl]oxy-N-(5-methylpyrazin-2-yl)benzamide
    SMILES
    CC1=CN=C(C=N1)NC(=O)C2=CC(=CC(=C2)OC(C)COC)OC3=NC=C(N=C3)C(=O)N4CCC4
    InChIKey
    FJEJHJINOKKDCW-INIZCTEOSA-N
    InChI
    1S/C24H26N6O5/c1-15-10-27-21(12-25-15)29-23(31)17-7-18(34-16(2)14-33-3)9-19(8-17)35-22-13-26-20(11-28-22)24(32)30-5-4-6-30/h7-13,16H,4-6,14H2,1-3H3,(Hshow more
    Synonyms
    (S)-3-(5-(Azetidine-1-carbonyl)pyrazin-2-yloxy)-5-(1-methoxypropan-2-yloxy)-N-(5-methylpyrazin-2-yl)benzamide | BA171...
  12. AR453588
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    AR453588
    CAS: 1065609-00-8 PubChem CID: 59291641 Formula: C25H25N7O2S2 Molecular Weight: 519.64
    ≥99%
    Out of Stock Item #: A647933
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    Technical Identifiers
    IUPAC Name
    1-[4-[5-[[3-(2-methylpyridin-3-yl)oxy-5-pyridin-2-ylsulfanylpyridin-2-yl]amino]-1,2,4-thiadiazol-3-yl]piperidin-1-yl]ethanone
    SMILES
    CC1=C(C=CC=N1)OC2=C(N=CC(=C2)SC3=CC=CC=N3)NC4=NC(=NS4)C5CCN(CC5)C(=O)C
    InChIKey
    WITGITFYEMHCEZ-UHFFFAOYSA-N
    InChI
    1S/C25H25N7O2S2/c1-16-20(6-5-11-26-16)34-21-14-19(35-22-7-3-4-10-27-22)15-28-24(21)30-25-29-23(31-36-25)18-8-12-32(13-9-18)17(2)33/h3-7,10-11,14-15,18show more
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