Sistema do complemento

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  1. Avacopan (CCX168), Antagonist of C5a 1 receptor
    CAS: 1346623-17-3 Número CE: 877-511-8 Fórmula: C33H35F4N3O2 Peso molecular: 581.64
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: A421311
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    Identificadores técnicos
    Nome IUPAC
    (2R,3S)-2-[4-(cyclopentylamino)phenyl]-1-(2-fluoro-6-methylbenzoyl)-N-[4-methyl-3-(trifluoromethyl)phenyl]piperidine-3-carboxamide
    SMILES
    CC1=C(C(=CC=C1)F)C(=O)N2CCCC(C2C3=CC=C(C=C3)NC4CCCC4)C(=O)NC5=CC(=C(C=C5)C)C(F)(F)F
    InChIKey
    PUKBOVABABRILL-YZNIXAGQSA-N
    InChI
    1S/C33H35F4N3O2/c1-20-12-15-25(19-27(20)33(35,36)37)39-31(41)26-10-6-18-40(32(42)29-21(2)7-5-11-28(29)34)30(26)22-13-16-24(17-14-22)38-23-8-3-4-9-23/hshow more
    Sinónimos
    (2R,3S)-2-[4-(Cyclopentylamino)phenyl]-1-(2-fluoro-6-methylbenzoyl)-N-[4-methyl-3-(trifluoromethyl)phenyl]-3-piperidi...
  2. Compstatin TFA
    CAS: 206645-99-0 Fórmula: C66H99N23O17S2.xC2HF3O2 Peso molecular: 1550.77(free basis)
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: C302746
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    Identificadores técnicos
    Nome IUPAC
    2-[(4R,7S,10S,13S,19S,22S,25S,28S,31S,34R)-4-[[(2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl]carbamoyl]-34-[[(2S,3S)-2-amino-3-methylpentanoyl]amino]-25-(show more
    SMILES
    CCC(C)C(C(=O)NC1CSSCC(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)CNC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC1=O)C(C)C)C(C)C)CCC(=O)N)CC(=O)O)CC2=CNC3=CC=CC=C32)CC4show more
    InChIKey
    RDTRHBCZFDCUPW-KWICJJCGSA-N
    InChI
    1S/C66H99N23O17S2/c1-8-32(6)50(68)63(104)86-46-27-108-107-26-45(62(103)89-53(33(7)90)54(69)95)85-56(97)39(14-11-17-74-66(70)71)80-59(100)43(20-36-24-7show more
    Sinónimos
    2-((4R,7S,10S,13S,19S,22S,25S,28S,31S,34R)-10,13-Bis((1H-imidazol-4-yl)methyl)-19-((1H-indol-3-yl)methyl)-4-(((2S,3R)...
  3. Danicopan (ACH-4471), Complement factor D inhibitor
    CAS: 1903768-17-1 Fórmula: C26H23BrFN7O3 Peso molecular: 580.41
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: D412556
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    Nome IUPAC
    (2S,4R)-1-[2-[3-acetyl-5-(2-methylpyrimidin-5-yl)indazol-1-yl]acetyl]-N-(6-bromopyridin-2-yl)-4-fluoropyrrolidine-2-carboxamide
    SMILES
    CC1=NC=C(C=N1)C2=CC3=C(C=C2)N(N=C3C(=O)C)CC(=O)N4CC(CC4C(=O)NC5=NC(=CC=C5)Br)F
    InChIKey
    PIBARDGJJAGJAJ-NQIIRXRSSA-N
    InChI
    1S/C26H23BrFN7O3/c1-14(36)25-19-8-16(17-10-29-15(2)30-11-17)6-7-20(19)35(33-25)13-24(37)34-12-18(28)9-21(34)26(38)32-23-5-3-4-22(27)31-23/h3-8,10-11,1show more
    Sinónimos
    BDBM354268 | JM8C1SFX0U | DANICOPAN [JAN] | 1903768-17-1 | MLS006011963 | Danicopan free base | MS-30411 | (2S,4R)-1-...
  4. EG 00229 trifluoroacetate
    CAS: 1210945-69-9 PubChem CID: 45142253 Fórmula: C17H19N7O5S3.CF3CO2H Peso molecular: 611.59
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: E287676
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    Identificadores técnicos
    Nome IUPAC
    (2S)-2-[[3-(2,1,3-benzothiadiazol-4-ylsulfonylamino)thiophene-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoic acid;2,2,2-trifluoroacetic acid
    SMILES
    C1=CC2=NSN=C2C(=C1)S(=O)(=O)NC3=C(SC=C3)C(=O)NC(CCCN=C(N)N)C(=O)O.C(=O)(C(F)(F)F)O
    InChIKey
    ZYQBITUOSRZDTG-MERQFXBCSA-N
    InChI
    1S/C17H19N7O5S3.C2HF3O2/c18-17(19)20-7-2-4-11(16(26)27)21-15(25)14-10(6-8-30-14)24-32(28,29)12-5-1-3-9-13(12)23-31-22-9;3-2(4,5)1(6)7/h1,3,5-6,8,11,24show more
    Sinónimos
    N2-[[3-[(2,1,3-Benzothiadiazol-4-ylsulfonyl)amino]-2-thienyl]carbonyl]-L-arginine trifluoroacetate
  5. Leukadherin-1
    CAS: 344897-95-6 Fórmula: C22H15NO4S2 Peso molecular: 421.49
    10mM in DMSO
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: L423514
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    Identificadores técnicos
    Nome IUPAC
    4-[5-[(Z)-(3-benzyl-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]furan-2-yl]benzoic acid
    SMILES
    C1=CC=C(C=C1)CN2C(=O)C(=CC3=CC=C(O3)C4=CC=C(C=C4)C(=O)O)SC2=S
    InChIKey
    AEZGRQSLKVNPCI-UNOMPAQXSA-N
    InChI
    1S/C22H15NO4S2/c24-20-19(29-22(28)23(20)13-14-4-2-1-3-5-14)12-17-10-11-18(27-17)15-6-8-16(9-7-15)21(25)26/h1-12H,13H2,(H,25,26)/b19-12-
    Sinónimos
    Leukadherin 1 | SCHEMBL18301010 | HY-15701 | (Z)-4-(5-((3-benzyl-4-oxo-2-thioxothiazolidin-5-ylidene)methyl)furan-2-y...
  6. PMX 53
    CAS: 219639-75-5 PubChem CID: 6918468 Fórmula: C47H65N11O7 Peso molecular: 896.1
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ◐ .Sob encomenda · 8–12 semanas Item #: P422637
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    Nome IUPAC
    (2S)-2-acetamido-N-[(3S,9S,12S,15R,18S)-15-(cyclohexylmethyl)-9-[3-(diaminomethylideneamino)propyl]-12-(1H-indol-3-ylmethyl)-2,8,11,14,17-pentaoxo-1,7show more
    SMILES
    CC(=O)NC(CC1=CC=CC=C1)C(=O)NC2CCCNC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C3CCCN3C2=O)CC4CCCCC4)CC5=CNC6=CC=CC=C65)CCCN=C(N)N
    InChIKey
    YOKBGCTZYPOSQM-HPSWDUTRSA-N
    InChI
    1S/C47H65N11O7/c1-29(59)53-37(25-30-13-4-2-5-14-30)42(61)55-36-20-11-22-50-41(60)35(19-10-23-51-47(48)49)54-44(63)39(27-32-28-52-34-18-9-8-17-33(32)34show more
  7. Phaseoloidin
    CAS: 118555-82-1 PubChem CID: 14104237 Fórmula: C14H18O9 Peso molecular: 330.29
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: P412861
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    Identificadores técnicos
    Nome IUPAC
    2-[5-hydroxy-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]acetic acid
    SMILES
    C1=CC(=C(C=C1O)CC(=O)O)OC2C(C(C(C(O2)CO)O)O)O
    InChIKey
    MVFYXXNAFZRZAM-RGCYKPLRSA-N
    InChI
    1S/C14H18O9/c15-5-9-11(19)12(20)13(21)14(23-9)22-8-2-1-7(16)3-6(8)4-10(17)18/h1-3,9,11-16,19-21H,4-5H2,(H,17,18)/t9-,11-,12+,13-,14-/m1/s1
    Sinónimos
    AKOS040758809 | MS-24951 | HY-N7400 | PHASEOLOIDIN | s3240 | [2-(beta-D-Glucopyranosyloxy)-5-hydroxyphenyl]acetic aci...
  8. Phaseoloidin
    CAS: 118555-82-1 PubChem CID: 14104237 Fórmula: C14H18O9 Peso molecular: 330.29
    10mM in DMSO
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: P420816
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    Identificadores técnicos
    Nome IUPAC
    2-[5-hydroxy-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]acetic acid
    SMILES
    C1=CC(=C(C=C1O)CC(=O)O)OC2C(C(C(C(O2)CO)O)O)O
    InChIKey
    MVFYXXNAFZRZAM-RGCYKPLRSA-N
    InChI
    1S/C14H18O9/c15-5-9-11(19)12(20)13(21)14(23-9)22-8-2-1-7(16)3-6(8)4-10(17)18/h1-3,9,11-16,19-21H,4-5H2,(H,17,18)/t9-,11-,12+,13-,14-/m1/s1
    Sinónimos
    AKOS040758809 | MS-24951 | HY-N7400 | PHASEOLOIDIN | s3240 | [2-(beta-D-Glucopyranosyloxy)-5-hydroxyphenyl]acetic aci...
  9. SB 290157 trifluoroacetate
    CAS: 1140525-25-2 PubChem CID: 16760645 Fórmula: C24H29F3N4O6 Peso molecular: 526.51
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: S287899
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    Identificadores técnicos
    Nome IUPAC
    (2S)-5-(diaminomethylideneamino)-2-[[2-(2,2-diphenylethoxy)acetyl]amino]pentanoic acid;2,2,2-trifluoroacetic acid
    SMILES
    C1=CC=C(C=C1)C(COCC(=O)NC(CCCN=C(N)N)C(=O)O)C2=CC=CC=C2.C(=O)(C(F)(F)F)O
    InChIKey
    ZJRMPPVJAQWGEG-FYZYNONXSA-N
    InChI
    1S/C22H28N4O4.C2HF3O2/c23-22(24)25-13-7-12-19(21(28)29)26-20(27)15-30-14-18(16-8-3-1-4-9-16)17-10-5-2-6-11-17;3-2(4,5)1(6)7/h1-6,8-11,18-19H,7,12-15H2show more
    Sinónimos
    N2-[2-(2,2-Diphenylethoxy)acetyl]-L-arginine trifluoroacetate | N2-[2-(2,2-diphenylethoxy)acetyl]-L-arginine, 2,2,2-t...
  10. SB 290157 trifluoroacetate
    CAS: 1140525-25-2 PubChem CID: 16760645 Fórmula: C24H29F3N4O6 Peso molecular: 526.51
    10mM in DMSO
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: S420706
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    Preços e tamanhos do pacote
    Identificadores técnicos
    Nome IUPAC
    (2S)-5-(diaminomethylideneamino)-2-[[2-(2,2-diphenylethoxy)acetyl]amino]pentanoic acid;2,2,2-trifluoroacetic acid
    SMILES
    C1=CC=C(C=C1)C(COCC(=O)NC(CCCN=C(N)N)C(=O)O)C2=CC=CC=C2.C(=O)(C(F)(F)F)O
    InChIKey
    ZJRMPPVJAQWGEG-FYZYNONXSA-N
    InChI
    1S/C22H28N4O4.C2HF3O2/c23-22(24)25-13-7-12-19(21(28)29)26-20(27)15-30-14-18(16-8-3-1-4-9-16)17-10-5-2-6-11-17;3-2(4,5)1(6)7/h1-6,8-11,18-19H,7,12-15H2show more
    Sinónimos
    N2-[2-(2,2-Diphenylethoxy)acetyl]-L-arginine trifluoroacetate | N2-[2-(2,2-diphenylethoxy)acetyl]-L-arginine, 2,2,2-t...
  11. Lipoteichoic acid from Bacillus subtilis
    CAS: 56411-57-5 Fórmula: C39H70N2O13 Peso molecular: 775
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: L487148
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    Identificadores técnicos
    Nome IUPAC
    [(2S)-1-[(2S,3R,4S,5R,6R)-4-[(2S,3R,4S,5R,6R)-3-acetamido-5-amino-4-hydroxy-6-methyloxan-2-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-heptashow more
    SMILES
    CCCCCCCC=CCCCCCC(=O)OC(COC1C(C(C(C(O1)CO)O)OC2C(C(C(C(O2)C)N)O)NC(=O)C)O)COC(=O)CCCCCC
    InChIKey
    PANDRCFROUDETH-YLSOAJEOSA-N
    InChI
    1S/C39H70N2O13/c1-5-7-9-11-12-13-14-15-16-17-18-20-22-31(45)52-28(24-49-30(44)21-19-10-8-6-2)25-50-39-36(48)37(34(46)29(23-42)53-39)54-38-33(41-27(4)4show more
  12. JR14a
    CAS: 2411440-41-8 PubChem CID: 145996525 Fórmula: C25H26Cl2N4O3S Peso molecular: 533.47
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: J573257
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    Identificadores técnicos
    Nome IUPAC
    (2S)-2-[[5-[bis(4-chlorophenyl)methyl]-3-methylthiophene-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoic acid
    SMILES
    CC1=C(SC(=C1)C(C2=CC=C(C=C2)Cl)C3=CC=C(C=C3)Cl)C(=O)NC(CCCN=C(N)N)C(=O)O
    InChIKey
    OHRIKWUZKGNQKQ-IBGZPJMESA-N
    InChI
    1S/C25H26Cl2N4O3S/c1-14-13-20(21(15-4-8-17(26)9-5-15)16-6-10-18(27)11-7-16)35-22(14)23(32)31-19(24(33)34)3-2-12-30-25(28)29/h4-11,13,19,21H,2-3,12H2,1show more
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Perguntas frequentes

What can I find under Complement System?
This listing collects compounds associated with Complement System within our Immunology/Inflammation area — inhibitors, agonists or antagonists, and reference tool compounds. Each entry links to its structure, CAS number, and reported activity so you can confirm the annotation before ordering.
What should I consider when picking a compound for Complement System?
Consider the reported potency of each Complement System compound and the assay behind it, selectivity against closely related targets, cell permeability if you are working in cells, and stability in your buffer. Two chemically distinct compounds giving the same phenotype is much stronger evidence than one.
What quality information is provided for Complement System compounds?
Each Complement System product page lists purity, identity data, molecular formula and weight, and storage conditions, with a lot-specific Certificate of Analysis available. Solubility and handling notes are on the datasheet. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search Complement System compounds by activity or structure?
Yes. Filter the Complement System listing by mechanism — inhibitor, agonist, antagonist — and search by target name or gene symbol, CAS number, molecular formula, or SMILES to reach exact structures and close analogs. For bulk quantities or items not listed, contact [email protected].

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