Recombinant Human IL-18 R alpha/IL-1 R5 Protein, ≥95% (SDS-PAGE)

Cat. No.: rp147455
AVAILABLE TO ORDER
GRADE & PURITY Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. His Tag ? His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. Fc tag ? Fc tag grade — recombinant protein bearing a Fc tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. The Fc tag aids dimerization and protein-A/G capture. ≥95%(SDS-PAGE)
Expression System
HEK293
Accession #
Q13478
Protein Tag
C-hFc & His
Expression system
HEK293
Endotoxin Concentration
<0.1 EU/μg
Bioactivity
Measured by its ability to inhibit the Recombinant Human IL-18 induced response on KG-1 human acute myelogenous leukemia cells in the presence of Recombinant Human IL-18 R beta /IL-1 R7 Fc Chimera . The ED50 for this effect is 0.400-4.00 μg/mL.
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
10μg
rp147455-10μg
≥10
$139.90
50μg
rp147455-50μg
8
$289.90
100μg
rp147455-100μg
3
$409.90
1mg
rp147455-1mg
1-2 wks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
$2,119.90
Enter a quantity for the sizes you want to add.
🧪

Why this grade

Animal Free,Carrier Free,Bioactive,ActiBioPure™,Azide Free,High Performance,His-Tag,Fc tag,≥95%(SDS-PAGE) ActiBioPure™,Animal Free,Azide Free,Bioactive,Carrier Free,Fc tag,High Performance,His Tag for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C,Avoid repeated freezing and thawing Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Purity
≥95% SDS-PAGE.
Endotoxin level
<0.1 EU/µg
Function
Receptor for interleukin 18 (IL-18). Binding to the agonist leads to the activation of NF-kappa-B.

Specifications

Product Name
Recombinant Human IL-18 R alpha/IL-1 R5 Protein, ≥95% (SDS-PAGE)
Synonyms
CD218a | CDw218a | IL18R1 | IL18RA | IL-18Ralpha | IL-18R-alpha | IL18Ralpha2 | IL1RRP | IL-1Rrp | Interleukin-18 receptor 1 | IL-1 R5 | IL-1 Rrp | IL-18 R alpha | IL-18 R1 | IL18R alpha | IL-18Ra | CD218 antigen-like family member A | CDw218a | EC 3.2.2.
Grade
ActiBioPure™, Animal Free, Azide Free, Bioactive, Carrier Free, Fc tag, High Performance, His Tag
Specifications & Purity
Animal Free, Carrier Free, Bioactive, ActiBioPure™, Azide Free, High Performance, His-Tag, Fc tag, ≥95%(SDS-PAGE)
Purity
≥95% (SDS-PAGE)
Bioactivity
Measured by its ability to inhibit the Recombinant Human IL-18 induced response on KG-1 human acute myelogenous leukemia cells in the presence of Recombinant Human IL-18 R beta /IL-1 R7 Fc Chimera . The ED50 for this effect is 0.400-4.00 μg/mL.
Endotoxin Concentration
<0.1 EU/μg
Expression System
HEK293
Species
Human
Amino Acids
20-329 aa
Sequence
ESCTSRPHITVVEGEPFYLKHCSCSLAHEIETTTKSWYKSSGSQEHVELNPRSSSRIALHDCVLEFWPVELNDTGSYFFQMKNYTQKWKLNVIRRNKHSCFTERQVTSKIVEVKKFFQITCENSYYQTLVNSTSLYKNCKKLLLENNKNPTIKKNAEFEDQGYYSCVHFLHHNGKLFNITKTFNITIVEDRSNIVPVLLGPKLNHVAVELGKNVRLNCSALLNEEDVIYWMFGEENGSDPNIHEEKEMRIMTPEGKWHASKVLRIENIGESNLNVLYNCTVASTGGTDTKSFILVRKADMADIPGHVFTRENLYFQGMDPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKHHHHHH
Protein Tag
C-Fc & His
Accession #
Predicted molecular weight
62 kDa
SDS-PAGE
80-100 kDa under reducing conditions.
Molecule Type
Protein
Storage and Shipping
Shape
Lyophilized
Reconstitution
Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
Storage
Store at -20°C,Avoid repeated freezing and thawing
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at -20~-80℃ for more than 1 year. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Images

Recombinant Human IL-18 R alpha/IL-1 R5 Protein (rp147455) - SDS-PAGE
3 μg/lane of Recombinant Human IL-18 R alpha/IL-1 R5 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 80 - 100 kDa.

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

6 results found

Lot NumberCertificate TypeDateItem
ZJ24F1215598Certificate of AnalysisJul 10, 2026 rp147455
ZJ24F1215599Certificate of AnalysisJul 10, 2026 rp147455
ZJ24F1215600Certificate of AnalysisJul 10, 2026 rp147455
ZJ24F0607398Certificate of AnalysisFeb 11, 2026 rp147455
ZJ24F0607399Certificate of AnalysisFeb 11, 2026 rp147455
ZJ24F0607400Certificate of AnalysisFeb 11, 2026 rp147455
Documents & Articles
Solution Calculators
Reviews

Customer Reviews

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.