Guaiacol - ≥98% , CAS No.90-05-1

Name: Guaiacol - ≥98% , CAS No.90-05-1
SKU: G112735
Availability: InStock

CAS: 90-05-1 Cat. No.: G112735 Formula: C₇H₈O₂ Molecular Weight: 124.14 Beilstein Registry Number: 508112 EC Number: 201-964-7

243 Citations COA

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Guaiacol - ≥98% CAS No(90-05-1) G112735 by Aladdin Scientific

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AVAILABLE TO ORDER

GRADE & PURITY ≥98%

Synonyms

Storage

Room temperature,Argon charged

Shipped In

Normal

Overview Specifications Names and Identifiers Documentation Advanced Data Taxonomic Classification 3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Documents & Articles Citations of This Product Solution Calculators Reviews Frequently Asked Questions

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Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Room temperature,Argon charged Ships Normal Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 243 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Guaiacol is a phenolic natural product first isolated from Guaiac resin, as well as the oxidation of lignin. Guaiacol is readily oxidized by the heme iron of peroxidases including the peroxidase of cyclooxygenase (COX) enzymes, hence it serves a reducing co-substrate for COX reactions.1 The color yield per peroxide at 470 nm is 6,650 (M peroxide reduced)-1 cm-1.2,3,4 Two moles of zguaiacol are oxidized for each mole of hydroperoxide reduced by the peroxidase. The resulting guaiacol chromophore can be used for the colorimetric determination of hydroperoxidase activity.
A phenolic natural product and reducing co-substrate for COX reactions.

Specifications

Synonyms

Specifications & Purity

≥98%

Biochemical and Physiological Mechanisms

愈创木酚和2，4，6-三氯苯甲醚是造成葡萄酒软木污染的原因

Storage

Room temperature,Argon charged

Shipped In

Normal

Purity

≥98%

Names and Identifiers

Pubchem Sid

504750391

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/504750391

Canonical Smiles

COC1=CC=CC=C1O

IUPAC Name

2-methoxyphenol

InChIKey

LHGVFZTZFXWLCP-UHFFFAOYSA-N

INCHI

1S/C7H8O2/c1-9-7-5-3-2-4-6(7)8/h2-5,8H,1H3

Isomeric SMILES

COC1=CC=CC=C1O

WGK Germany

RTECS

SL7525000

Molecular Weight

124.14

Beilstein

508112

Reaxy-Rn

508112

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=508112&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Benzenoids
  - Class Phenols
    - Subclass Methoxyphenols

Kingdom	Organic compounds
Superclass	Benzenoids
Class	Phenols
Subclass	Methoxyphenols
Intermediate Tree Nodes	Not available
Direct Parent	Methoxyphenols
Alternative Parents	Phenoxy compounds Methoxybenzenes Anisoles Alkyl aryl ethers 1-hydroxy-4-unsubstituted benzenoids 1-hydroxy-2-unsubstituted benzenoids Hydrocarbon derivatives
Molecular Framework	Aromatic homomonocyclic compounds
Substituents	Methoxyphenol - Phenoxy compound - Methoxybenzene - Phenol ether - Anisole - 1-hydroxy-4-unsubstituted benzenoid - 1-hydroxy-2-unsubstituted benzenoid - Alkyl aryl ether - Monocyclic benzene moiety - Ether - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Aromatic homomonocyclic compound
Description	This compound belongs to the class of organic compounds known as methoxyphenols. These are compounds containing a methoxy group attached to the benzene ring of a phenol moiety.
External Descriptors	a guaiacol
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

3D Structure

Associated Targets(Human)

CA2 Tclin Carbonic anhydrase II (17698 Activities)

Discover Target: CA2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ALOX5 Tclin Arachidonate 5-lipoxygenase (6568 Activities)

Discover Target: ALOX5

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

AR Tclin Androgen Receptor (11781 Activities)

Discover Target: AR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TYR Tclin Tyrosinase (717 Activities)

Discover Target: TYR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TSHR Tclin Thyroid stimulating hormone receptor (29986 Activities)

Discover Target: TSHR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CACNA1C Tclin Voltage-gated L-type calcium channel alpha-1C subunit (766 Activities)

Discover Target: CACNA1C

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CA1 Tclin Carbonic anhydrase I (13240 Activities)

Discover Target: CA1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MMP3 Tchem Matrix metalloproteinase 3 (3433 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MMP8 Tchem Matrix metalloproteinase 8 (1942 Activities)

Discover Target: MMP8

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MMP1 Tchem Matrix metalloproteinase-1 (7046 Activities)

Discover Target: MMP1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TP53 Tchem Cellular tumor antigen p53 (48468 Activities)

Discover Target: TP53

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

U-251 (51189 Activities)

Lot Number	Certificate Type	Date	Item
A23311040	Certificate of Analysis	Aug 03, 2026	G112735
G2613341	Certificate of Analysis	Jun 29, 2026	G112735
G2613340	Certificate of Analysis	Jun 29, 2026	G112735
G2613339	Certificate of Analysis	Jun 29, 2026	G112735
G2613338	Certificate of Analysis	Jun 29, 2026	G112735
B2628430	Certificate of Analysis	Jan 23, 2026	G112735
B2628570	Certificate of Analysis	Jan 23, 2026	G112735
B2628579	Certificate of Analysis	Jan 23, 2026	G112735
A2423056	Certificate of Analysis	Oct 13, 2025	G112735
G2516172	Certificate of Analysis	Jul 08, 2025	G112735
L2510046	Certificate of Analysis	Jul 08, 2025	G112735
K2512101	Certificate of Analysis	Jul 08, 2025	G112735
G2516434	Certificate of Analysis	Jul 08, 2025	G112735
G2516433	Certificate of Analysis	Jul 08, 2025	G112735
K2111110	Certificate of Analysis	May 07, 2025	G112735
K2111108	Certificate of Analysis	May 07, 2025	G112735
G2123125	Certificate of Analysis	Jan 16, 2025	G112735
F2509113	Certificate of Analysis	Jul 16, 2024	G112735
J2428662	Certificate of Analysis	Jul 16, 2024	G112735
J2428668	Certificate of Analysis	Jul 16, 2024	G112735
A2503871	Certificate of Analysis	Jul 16, 2024	G112735
A2503161	Certificate of Analysis	Aug 04, 2023	G112735
K2111107	Certificate of Analysis	Aug 04, 2023	G112735
J2428256	Certificate of Analysis	Dec 28, 2022	G112735
A23311041	Certificate of Analysis	Dec 28, 2022	G112735
A23311043	Certificate of Analysis	Dec 28, 2022	G112735
B2301901	Certificate of Analysis	Dec 28, 2022	G112735
E2015035	Certificate of Analysis	Apr 13, 2022	G112735
K2215095	Certificate of Analysis	Oct 14, 2021	G112735
G2123127	Certificate of Analysis	Jul 12, 2021	G112735
G2123126	Certificate of Analysis	Jul 12, 2021	G112735

Solubility	Miscible with carbon tetrachloride, alcohol, chloroform, ether, oils, glacial acetic acid and sodium hydroxide solution. Slightly miscible with water and petroleum ether.
Sensitivity	Light & Air & Moisture sensitive
Freezing Point(°C)	28 °C
Refractive Index	1.543-1.545
Flash Point(°F)	179.6 °F
Flash Point(°C)	82℃
Boil Point(°C)	205°C
Melt Point(°C)	27-29°C
Molecular Weight	124.140 g/mol
XLogP3	1.300
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	1
Exact Mass	124.052 Da
Monoisotopic Mass	124.052 Da
Topological Polar Surface Area	29.500 Å²
Heavy Atom Count	9
Formal Charge	0
Complexity	83.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Guaiacol - ≥98% , CAS No.90-05-1

Storage & shipping

Quality documents

Literature proof

Overview

Specifications

Documentation

📋 Safety Data Sheet (SDS)

✅ Certificate of Analysis (COA)

📊 Datasheet

🔬 Specification Sheet

Advanced Data

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

Customer Reviews

Frequently Asked Questions

📚 Citations by Application

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