Immunoglobulin E (IgE) from Normal Human Plasma

Cat. No.: np001077

GRADE & PURITY Bioactive, ActiBioPure™, Native, High Performance, EnzymoPure™, ≥95%(SDS-PAGE), Protein concentration: See COA

Accession #

P01854

Overview

IgE is the least abundant immunoglobulin in plasma, found at a concentration of less that 0.6 micrograms/ml of normal plasma. Elevated IgE levels are found in patients experiencing severe allergic reactions and parasitic infections. In a myeloma condition, IgE is produced by a single clone of plasma cells. The structure of myeloma IgE, however, is normal, and the immunoglobulin purified from a myeloma source is a useful protein for studying immunoglobulin behavior.

Prepared from plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.

Specifications

Product Name

Immunoglobulin E (IgE) from Normal Human Plasma

Synonyms

Immunoglobulin E | IGHE | IgE

Grade

ActiBioPure™, Bioactive, High Performance, Native, EnzymoPure™

Specifications & Purity

Bioactive, ActiBioPure™, Native, High Performance, EnzymoPure™, ≥95%(SDS-PAGE), Protein concentration: See COA

Biochemical and Physiological Mechanisms

Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as re

Accession #

P01854

Predicted molecular weight

200 kDa

Molecule Type

Protein

Storage and Shipping

Shape

Frozen in 100 mM Tris, pH 7.5, with 200 mM NaCl and 0.05% sodium azide.

Concentration

Protein concentration: See COA

Storage

Store at -20°C,Avoid repeated freezing and thawing

Shipped In

Ice chest + Ice pads

Stability And Storage

Store at -20℃ long term (>1 year). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

References

1. Jintao Liang, Shuaikang Dong, Xiaohong Tan, Junyan Gong, Xuyang Chen, Zhide Zhou, Guiyin Li.  (2025)  A high-sensitivity label-free electrochemical aptasensor for point-of-care measurements of low-density lipoprotein in plasma based on aptamer and MXene-CMCS-Hemin nanocomposites.  BIOELECTROCHEMISTRY,      [PMID:40138878] [10.1016/j.bioelechem.2025.108972]

2. Liang Jintao, Yu Tingting, Tan Xiaohong, Jiang Lizhi, He Wei, Zhan Yulian, Huang Yong, Zhou Zhide, Li Guiyin.  (2024)  High-Precision Fluorescence Platform for Point-of-Care Measurements of Low-Density Lipoprotein Based on Nitrogen, Sulfur-Doped Graphene Quantum Dots and Ferric Tetroxide @ Reduced Graphene Oxide.  BioNanoScience,  15  (1): (1-14).  [PMID:] [10.1007/s12668-024-01618-3]