Immunoglobulin E (IgE) from Normal Human Plasma

Cat. No.: np001077

GRADE & PURITY Bioactive, ActiBioPure™, Native, High Performance, EnzymoPure™, ≥95%(SDS-PAGE), Protein concentration: See COA

Accession #

P01854

Overview

IgE is the least abundant immunoglobulin in plasma, found at a concentration of less that 0.6 micrograms/ml of normal plasma. Elevated IgE levels are found in patients experiencing severe allergic reactions and parasitic infections. In a myeloma condition, IgE is produced by a single clone of plasma cells. The structure of myeloma IgE, however, is normal, and the immunoglobulin purified from a myeloma source is a useful protein for studying immunoglobulin behavior.

Prepared from plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.

Specifications

Product Name

Immunoglobulin E (IgE) from Normal Human Plasma

Synonyms

Immunoglobulin E | IGHE | IgE

Grade

ActiBioPure™, Bioactive, High Performance, Native, EnzymoPure™

Specifications & Purity

Bioactive,ActiBioPure™,Native,High Performance,EnzymoPure™,≥95%(SDS-PAGE),Protein concentration: See COA

Biochemical and Physiological Mechanisms

Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as re

Accession #

P01854

Predicted molecular weight

200 kDa

Molecule Type

Protein

Storage and Shipping

Shape

Frozen in 100 mM Tris, pH 7.5, with 200 mM NaCl and 0.05% sodium azide.

Concentration

Protein concentration: See COA

Storage

Store at -20°C,Avoid repeated freezing and thawing

Shipped In

Ice chest + Ice pads

Stability And Storage

Store at -20℃ long term (>1 year). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

References

1. Jintao Liang, Shuaikang Dong, Xiaohong Tan, Junyan Gong, Xuyang Chen, Zhide Zhou, Guiyin Li.  (2025)  A high-sensitivity label-free electrochemical aptasensor for point-of-care measurements of low-density lipoprotein in plasma based on aptamer and MXene-CMCS-Hemin nanocomposites.  BIOELECTROCHEMISTRY,      [PMID:40138878] [10.1016/j.bioelechem.2025.108972]

2. Liang Jintao, Yu Tingting, Tan Xiaohong, Jiang Lizhi, He Wei, Zhan Yulian, Huang Yong, Zhou Zhide, Li Guiyin.  (2024)  High-Precision Fluorescence Platform for Point-of-Care Measurements of Low-Density Lipoprotein Based on Nitrogen, Sulfur-Doped Graphene Quantum Dots and Ferric Tetroxide @ Reduced Graphene Oxide.  BioNanoScience,  15  (1): (1-14).  [PMID:] [10.1007/s12668-024-01618-3]

Frequently Asked Questions

What is the purity of this product, and how is it determined?

This product is supplied at ≥95% purity, determined by SDS-PAGE. Lot-specific values are stated on the Certificate of Analysis.

What is ActiBioPure??

ActiBioPure? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, ActiBioPure? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

What does Bioactive mean?

Bioactive indicates that the product has been processed and tested for biological and biochemical applications. Specifications may include endotoxin limits, microbial controls, sterility, low DNase/RNase/protease activity, and verified biological activity where relevant.

How should this product be stored?

Store at ?20 °C. Avoid repeated freeze–thaw cycles. Aliquot into single-use volumes before freezing.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.