Overview Specifications Names and Identifiers Documentation Advanced Data Taxonomic Classification 3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Documents & Articles Citations of This Product Solution Calculators Reviews

🧪

Why this grade

Moligand™, ≥99% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Protected from light,Room temperature,Argon charged,Desiccated Ships Normal Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 1644 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

L-cysteine is a sulfur-containing non-essential amino acid.Its ability to reduce colitis symptoms is being assessed for potential use in treating inflammatory bowel disease (IBD).

Naturally occurring non-essential amino acid.

A non-essential amino acid.

L-cysteine can be used as a cysteine source to prepare L-cysteine functionalized gold nanoparticles for use as probes in the colorimetric detection of Hg2+ in aqueous solution.

Specifications

Synonyms

Specifications & Purity

Moligand™, ≥99%

Biochemical and Physiological Mechanisms

NMDA glutamatergic receptor agonist.

Storage

Protected from light,Room temperature,Argon charged,Desiccated

Shipped In

Normal

Grade

Moligand™

Purity

≥99%

Names and Identifiers

Pubchem Sid

508810639

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/508810639

Canonical Smiles

C(C(C(=O)O)N)S

IUPAC Name

(2R)-2-amino-3-sulfanylpropanoic acid

InChIKey

XUJNEKJLAYXESH-REOHCLBHSA-N

INCHI

1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/t2-/m0/s1

Isomeric SMILES

C([C@@H](C(=O)O)N)S

Molecular Weight

121.16

Beilstein

4506

Reaxy-Rn

1721406

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1721406&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organic acids and derivatives
  - Class Carboxylic acids and derivatives
    - Subclass Amino acids, peptides, and analogues
      - Level5 Amino acids and derivatives
        Level6 Alpha amino acids and derivatives
        Level7 Cysteine and derivatives

Kingdom	Organic compounds
Superclass	Organic acids and derivatives
Class	Carboxylic acids and derivatives
Subclass	Amino acids, peptides, and analogues
Intermediate Tree Nodes	Amino acids and derivatives - Alpha amino acids and derivatives
Direct Parent	Cysteine and derivatives
Alternative Parents	L-alpha-amino acids Amino acids Monocarboxylic acids and derivatives Carboxylic acids Alkylthiols Organopnictogen compounds Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds
Molecular Framework	Aliphatic acyclic compounds
Substituents	Cysteine or derivatives - Alpha-amino acid - L-alpha-amino acid - Amino acid - Alkylthiol - Carboxylic acid - Monocarboxylic acid or derivatives - Organic oxygen compound - Primary amine - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Organic nitrogen compound - Primary aliphatic amine - Carbonyl group - Amine - Hydrocarbon derivative - Organopnictogen compound - Organic oxide - Aliphatic acyclic compound
Description	This compound belongs to the class of organic compounds known as cysteine and derivatives. These are compounds containing cysteine or a derivative thereof resulting from reaction of cysteine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom.
External Descriptors	Common amino acids
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

3D Structure

Associated Targets(Human)

F2 Tclin Thrombin (11687 Activities)

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ESR1 Tclin Estrogen receptor alpha (17718 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PGR Tclin Progesterone receptor (8562 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADRA2A Tclin Alpha-2a adrenergic receptor (9450 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

AR Tclin Androgen Receptor (11781 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MAOA Tclin Monoamine oxidase A (11911 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

DRD1 Tclin Dopamine D1 receptor (9720 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ACHE Tclin Acetylcholinesterase (18204 Activities)

Discover Target: ACHE

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC6A2 Tclin Norepinephrine transporter (10102 Activities)

Discover Target: SLC6A2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC6A4 Tclin Serotonin transporter (12625 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADRA1A Tclin Alpha-1a adrenergic receptor (8359 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

OPRM1 Tclin Mu opioid receptor (19785 Activities)

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DRD3 Tclin Dopamine D3 receptor (14368 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC6A3 Tclin Dopamine transporter (10535 Activities)

Discover Target: SLC6A3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PDE3A Tclin Phosphodiesterase 3A (3309 Activities)

Discover Target: PDE3A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HTR2B Tclin Serotonin 2b (5-HT2b) receptor (10323 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TBXA2R Tclin Thromboxane A2 receptor (5717 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PDE4A Tclin Phosphodiesterase 4A (1943 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADORA3 Tchem Adenosine A3 receptor (15931 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GSTM1 Tbio Glutathione S-transferase Mu 1 (61 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HRH3 Tclin Histamine H3 receptor (10389 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CPA1 Tchem Carboxypeptidase A1 (146 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

KDR Tclin Vascular endothelial growth factor receptor 2 (20924 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC1A1 Tchem Excitatory amino acid transporter 3 (527 Activities)

Discover Target: SLC1A1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC1A3 Tchem Excitatory amino acid transporter 1 (586 Activities)

Discover Target: SLC1A3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GSTK1 Tchem Glutathione S-transferase kappa 1 (56 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Homo sapiens (32628 Activities)

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HeLa (62764 Activities)

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KIF11 Tchem Kinesin-like protein 1 (1720 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC7A11 Tchem Cystine/glutamate transporter (150 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC36A1 Tchem Proton-coupled amino acid transporter 1 (102 Activities)

Discover Target: SLC36A1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Pkm Pyruvate kinase isozymes M1/M2 (66 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mus musculus (284745 Activities)

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Rattus norvegicus (775804 Activities)

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H9c2 (3506 Activities)

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rep Replicase polyprotein 1ab (378 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Slc16a10 Monocarboxylate transporter 10 (73 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

cAMP-specific 3',5'-cyclic phosphodiesterase 4B (18 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

spt Serine palmitoyltransferase (15 Activities)

Discover Target: spt

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Slc1a5 Amino acid transporter (271 Activities)

Discover Target: Slc1a5

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SARS-CoV-2 (38078 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

74 results found

Lot Number	Certificate Type	Date	Item
A2606082	Certificate of Analysis	Sep 22, 2026	C108237
L2517263	Certificate of Analysis	Sep 21, 2026	C108237
L2517250	Certificate of Analysis	Sep 21, 2026	C108237
L2517252	Certificate of Analysis	Sep 21, 2026	C108237
L2517253	Certificate of Analysis	Sep 21, 2026	C108237
F2405157	Certificate of Analysis	Sep 01, 2026	C108237
I2512236	Certificate of Analysis	Jul 14, 2026	C108237
L2420659	Certificate of Analysis	Jul 03, 2026	C108237
B2628476	Certificate of Analysis	Feb 07, 2026	C108237
B2628475	Certificate of Analysis	Feb 07, 2026	C108237
B2628482	Certificate of Analysis	Feb 07, 2026	C108237
B2628481	Certificate of Analysis	Feb 07, 2026	C108237
B2628480	Certificate of Analysis	Feb 07, 2026	C108237
F2427075	Certificate of Analysis	Jan 20, 2026	C108237
F2415174	Certificate of Analysis	Dec 12, 2025	C108237
L2517254	Certificate of Analysis	Dec 09, 2025	C108237
L2517251	Certificate of Analysis	Dec 09, 2025	C108237
H2624060	Certificate of Analysis	Dec 09, 2025	C108237
A2404897	Certificate of Analysis	Jul 14, 2025	C108237
F2527279	Certificate of Analysis	Jun 21, 2025	C108237
F2527316	Certificate of Analysis	Jun 21, 2025	C108237
F2527326	Certificate of Analysis	Jun 21, 2025	C108237
F2527332	Certificate of Analysis	Jun 21, 2025	C108237
F2527336	Certificate of Analysis	Jun 21, 2025	C108237
F2527337	Certificate of Analysis	Jun 21, 2025	C108237
I2512133	Certificate of Analysis	Jun 21, 2025	C108237
I2512135	Certificate of Analysis	Jun 21, 2025	C108237
I2512235	Certificate of Analysis	Jun 21, 2025	C108237
K2505010	Certificate of Analysis	Jun 21, 2025	C108237
F2415171	Certificate of Analysis	Apr 18, 2025	C108237
F2426270	Certificate of Analysis	Apr 08, 2025	C108237
F2415178	Certificate of Analysis	Mar 04, 2025	C108237
F2415200	Certificate of Analysis	Mar 04, 2025	C108237
L2420661	Certificate of Analysis	Dec 13, 2024	C108237
C2525068	Certificate of Analysis	Dec 13, 2024	C108237
F2527048	Certificate of Analysis	Dec 13, 2024	C108237
L2420656	Certificate of Analysis	Dec 13, 2024	C108237
L2420658	Certificate of Analysis	Dec 13, 2024	C108237
A2404210	Certificate of Analysis	Oct 23, 2024	C108237
A2404898	Certificate of Analysis	Oct 23, 2024	C108237
K2427240	Certificate of Analysis	Oct 23, 2024	C108237
G2219341	Certificate of Analysis	Oct 23, 2024	C108237
G2219359	Certificate of Analysis	Oct 23, 2024	C108237
D2115213	Certificate of Analysis	Oct 18, 2024	C108237
G2430050	Certificate of Analysis	Aug 01, 2024	C108237
J2412430	Certificate of Analysis	Jun 27, 2024	C108237
J2412429	Certificate of Analysis	Jun 27, 2024	C108237
G2412020	Certificate of Analysis	Jun 06, 2024	C108237
J2415162	Certificate of Analysis	Jun 06, 2024	C108237
F2415179	Certificate of Analysis	Jun 06, 2024	C108237
G2219340	Certificate of Analysis	Jan 12, 2024	C108237
F2222304	Certificate of Analysis	Jan 12, 2024	C108237
F2222307	Certificate of Analysis	Jan 12, 2024	C108237
D2409026	Certificate of Analysis	Dec 23, 2023	C108237
E2413023	Certificate of Analysis	Dec 23, 2023	C108237
B2422140	Certificate of Analysis	Dec 23, 2023	C108237
A2015103	Certificate of Analysis	Nov 20, 2023	C108237
E2317676	Certificate of Analysis	Apr 21, 2023	C108237
E2317677	Certificate of Analysis	Apr 21, 2023	C108237
E2317833	Certificate of Analysis	Apr 21, 2023	C108237
E2317682	Certificate of Analysis	Apr 21, 2023	C108237
E2317683	Certificate of Analysis	Apr 21, 2023	C108237
E2317684	Certificate of Analysis	Apr 21, 2023	C108237
E2317844	Certificate of Analysis	Apr 21, 2023	C108237
J2218537	Certificate of Analysis	Oct 12, 2022	C108237
J2218536	Certificate of Analysis	Oct 12, 2022	C108237
J2218533	Certificate of Analysis	Oct 12, 2022	C108237
J2218504	Certificate of Analysis	Oct 12, 2022	C108237
G2219365	Certificate of Analysis	Jul 05, 2022	C108237
G2219336	Certificate of Analysis	Jul 05, 2022	C108237
F2222302	Certificate of Analysis	Jun 15, 2022	C108237
F2222306	Certificate of Analysis	Jun 15, 2022	C108237
F2222308	Certificate of Analysis	Jun 15, 2022	C108237
F2110031	Certificate of Analysis	Jun 16, 2021	C108237

Chemical and Physical Properties

Solubility	Soluble in water, alcohol, acetic acid and aqueous ammonia. Insoluble in ether, acetone, ethyl acetate, benzene, carbon disulfide and carbon tetrachloride
Sensitivity	Light & Air sensitive
Specific Rotation[α]	8.8 ° (C=8, 1mol/L HCl)
Melt Point(°C)	220°C
Molecular Weight	121.160 g/mol
XLogP3	-2.500
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	2
Exact Mass	121.02 Da
Monoisotopic Mass	121.02 Da
Topological Polar Surface Area	64.300 Å²
Heavy Atom Count	7
Formal Charge	0
Complexity	75.300
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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Controlled-release & nanoparticle carrier69

Cancer cell line characterization20

Cell viability42

Nanoparticle / material biocompatibility76

Immune cell assay2

Chromatography (HPLC / GC / TLC)54

Cytotoxicity screening62

Cell proliferation9

Polymer synthesis & polymerization39

Tablet binder1

Film coating3

Cross-coupling reactions12

IC50 determination6

Crystallization & recrystallization10

Antioxidant activity assessment1

Antibacterial activity evaluation1

Environmental Sensing1

Sustained-release matrix2

Topical & ophthalmic formulation3

Thickener / viscosity modifier1

Environmental applications1

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L-Cysteine - Moligand™, ≥99% , CAS No.52-90-4

Storage & shipping

Quality documents

Literature proof

Overview

Specifications

Documentation

📋 Safety Data Sheet (SDS)

✅ Certificate of Analysis (COA)

📊 Datasheet

🔬 Specification Sheet

Advanced Data

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

Customer Reviews

📚 Citations by Application

Need help choosing the grade?

View related series

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