L-Tryptophan - PharmPure™,USP,JP,BP,Ph.Eur. , CAS No.73-22-3

CAS: 73-22-3 Cat. No.: L774650 Formula: C₁₁H₁₂N₂O₂ Molecular Weight: 204.23 Beilstein Registry Number: 86197 EC Number: 200-795-6

GRADE & PURITY PharmPure™, USP, JP, BP, Ph.Eur.

Synonyms

(S)-2-Amino-3-(3-indolyl)propionic acid | h-Trp-oh | L-Trytophan

Storage

Protected from light,Room temperature

Shipped In

Normal

Overview

EMPROVE®EXPERT Ph Eur,BP,JP,USP

Light sensitive. Quickly heat up to 289 ℃ for decomposition. Dissolved in hot ethanol, hydroxide alkali solution, and dilute hydrochloric acid, slightly soluble in water, insoluble in chloroform and ether. The aqueous solution exhibits a weak acidic reaction.

Specifications

Synonyms

(S)-2-Amino-3-(3-indolyl)propionic acid | h-Trp-oh | L-Trytophan

Specifications & Purity

PharmPure™,USP,JP,BP,Ph.Eur.

Biochemical and Physiological Mechanisms

Tryptophan (Trp) is a heterocyclic compound that is an essential amino acid associated with growth, reproduction, and immunity. Increasing the availability of tryptophan is necessary for regulating emotions, cognition, and behavior. The brain's uptake of

Storage

Protected from light,Room temperature

Shipped In

Normal

Grade

BP, JP, Ph.Eur., PharmPure™, USP

Names and Identifiers

Canonical Smiles

C1=CC=C2C(=C1)C(=CN2)CC(C(=O)O)N

IUPAC Name

(2S)-2-amino-3-(1H-indol-3-yl)propanoic acid

InChIKey

QIVBCDIJIAJPQS-VIFPVBQESA-N

INCHI

1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)/t9-/m0/s1

Isomeric SMILES

C1=CC=C2C(=C1)C(=CN2)C[C@@H](C(=O)O)N

Molecular Weight

204.23

Beilstein

86197

Reaxy-Rn

86196

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=86196&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Class Indoles and derivatives
      • Subclass Indolyl carboxylic acids and derivatives

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Class: Indoles and derivatives
• Subclass: Indolyl carboxylic acids and derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Indolyl carboxylic acids and derivatives
• Alternative Parents: L-alpha-amino acids 3-alkylindoles Aralkylamines Substituted pyrroles Benzenoids Heteroaromatic compounds Amino acids Monocarboxylic acids and derivatives Carboxylic acids Azacyclic compounds Organopnictogen compounds Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Indolyl carboxylic acid derivative - Alpha-amino acid - Alpha-amino acid or derivatives - L-alpha-amino acid - 3-alkylindole - Indole - Aralkylamine - Benzenoid - Substituted pyrrole - Heteroaromatic compound - Pyrrole - Amino acid or derivatives - Amino acid - Carboxylic acid derivative - Carboxylic acid - Monocarboxylic acid or derivatives - Azacycle - Amine - Primary aliphatic amine - Hydrocarbon derivative - Organic oxide - Organic oxygen compound - Organic nitrogen compound - Carbonyl group - Organonitrogen compound - Organooxygen compound - Primary amine - Organopnictogen compound - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as indolyl carboxylic acids and derivatives. These are compounds containing a carboxylic acid chain (of at least 2 carbon atoms) linked to an indole ring.
• External Descriptors: Common amino acids

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: 10g/L
• Sensitivity: light sensitive
• Specific Rotation[α]: -30.5 to -32.5 deg(C=1, H2O)
• Melt Point(°C): 277°C
• Molecular Weight: 204.220 g/mol
• XLogP3: -1.100
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 204.09 Da
• Monoisotopic Mass: 204.09 Da
• Topological Polar Surface Area: 79.100 Ų
• Heavy Atom Count: 15
• Formal Charge: 0
• Complexity: 245.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Frequently Asked Questions

What does PharmPure? mean?

PharmPure? refers to material produced and controlled to meet the requirements of pharmaceutical manufacturing and regulated workflows. Depending on the specific designation (GMP, RUO, Bio-medical, Injection grade, etc.), this may include controlled manufacturing environments, validated processes, audit-ready documentation and traceability.

What does USP mean?

USP indicates that the material complies with the published monographs of the relevant pharmacopoeia (USP). Specifications include identity, assay, impurity limits, residual solvents and other tests defined in the monograph. USP-compliant material is suitable for pharmacopoeia-compliant pharmaceutical use, including pharmaceutical manufacturing, QC and regulatory submission.

How should this product be stored?

Store at room temperature, protected from light. The material is light-sensitive — keep it in its original opaque or amber container.

How is this product shipped?

This product ships under standard ambient conditions. No temperature-controlled packaging is required.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 73-22-3, the molecular formula is C11H12N2O2, and the molecular weight is 204.23 g/mol. InChIKey QIVBCDIJIAJPQS-VIFPVBQESA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.