2M in THF/n-hexanes for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C,Argon charged Ships Wet ice Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 8 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Lithium diisopropylamide (LDA) is a hindered non-nucleophilic strong base that abstracts hydrogen from active carbon. It can be prepared from diisopropylamine and butyllithium in the presence of tetrahydrofuran.
Application
Lithium diisopropylamide can be used for the generation of carbanion or enolate anions from carbonyl group-containing compounds. It can also be used as a base in: The direct alkylation and acylation of ketones. The aldol condensation reaction. α-Selenation reaction. The synthesis of α, β- unsaturated carbonyl compounds from carbonyl compounds. The alkylation of acids, esters, amides, and nitriles. The initiation of anionic polymerization.
| Isomeric SMILES | [Li+].CC(C)[N-]C(C)C |
|---|---|
| WGK Germany | 3 |
| PubChem CID | 2724682 |
| Molecular Weight | 107.12 |
| Beilstein | 3655042 |
| Reaxy-Rn | 906717 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 G2623347 | Certificate of Analysis | Jul 06, 2026 | L432709 |
| G2623348 | Certificate of Analysis | Jul 06, 2026 | L432709 |
| E2621401 | Certificate of Analysis | May 11, 2026 | L432709 |
| E2621423 | Certificate of Analysis | May 11, 2026 | L432709 |
| B2625620 | Certificate of Analysis | Feb 03, 2026 | L432709 |
| B2625621 | Certificate of Analysis | Feb 03, 2026 | L432709 |
| K2512381 | Certificate of Analysis | Nov 04, 2025 | L432709 |
| K2512382 | Certificate of Analysis | Nov 04, 2025 | L432709 |
| I2517577 | Certificate of Analysis | Sep 02, 2025 | L432709 |
| I2517578 | Certificate of Analysis | Sep 02, 2025 | L432709 |
| G2509591 | Certificate of Analysis | Apr 14, 2025 | L432709 |
| G2509592 | Certificate of Analysis | Apr 14, 2025 | L432709 |
| B2527486 | Certificate of Analysis | Nov 15, 2024 | L432709 |
| B2527487 | Certificate of Analysis | Nov 15, 2024 | L432709 |
| B2527488 | Certificate of Analysis | Nov 15, 2024 | L432709 |
| Sensitivity | Moisture & heat & air sensitive |
|---|---|
| Flash Point(°F) | 35.6 °F |
| Flash Point(°C) | -18 °C |
| Boil Point(°C) | 60-136°C |
