Lithium diisopropylamide solution（LDA） - 2M in THF/n-hexanes , CAS No.4111-54-0

CAS: 4111-54-0 Cat. No.: L432709 Molecular Weight: 107.12 Beilstein Registry Number: 3655042 EC Number: 223-893-0 PubChem CID: 2724682

GRADE & PURITY 2M in THF/n-hexanes

Synonyms

L0171 | lithium N,N-diisopropylamide | DIISOPROPYLAMINE LITHIUM SALT [MI] | diisopropylamino lithium | OL028KIW1I | Lithium diisopropylamide

Storage

Store at 2-8°C,Argon charged

Shipped In

Wet ice

Overview

Lithium diisopropylamide (LDA) is a hindered non-nucleophilic strong base that abstracts hydrogen from active carbon. It can be prepared from diisopropylamine and butyllithium in the presence of tetrahydrofuran.

Application

Lithium diisopropylamide can be used for the generation of carbanion or enolate anions from carbonyl group-containing compounds. It can also be used as a base in: The direct alkylation and acylation of ketones. The aldol condensation reaction. α-Selenation reaction. The synthesis of α, β- unsaturated carbonyl compounds from carbonyl compounds. The alkylation of acids, esters, amides, and nitriles. The initiation of anionic polymerization.

Specifications

Synonyms

L0171 | lithium N, N-diisopropylamide | DIISOPROPYLAMINE LITHIUM SALT [MI] | diisopropylamino lithium | OL028KIW1I | Lithium diisopropylamide

Specifications & Purity

2M in THF/n-hexanes

Storage

Store at 2-8°C, Argon charged

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

• Isomeric SMILES: [Li+].CC(C)[N-]C(C)C
• WGK Germany: 3
• PubChem CID: 2724682
• Molecular Weight: 107.12
• Beilstein: 3655042
• Reaxy-Rn: 906717

Chemical and Physical Properties

• Sensitivity: Moisture & heat & air sensitive
• Flash Point(°F): 35.6 °F
• Flash Point(°C): -18 °C
• Boil Point(°C): 60-136°C

References

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