Pancreatin from porcine pancreas, CAS No.8049-47-6

CAS: 8049-47-6 Cat. No.: P755357 EC Number: 232-468-9
AVAILABLE TO ORDER
GRADE & PURITY Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Native ? Native grade — protein/biomolecule in its natural (non-recombinant, non-denatured) form. Use when native structure and activity are required. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. EnzymoPure™ ? EnzymoPure™ — Aladdin's line of high-quality enzymatic solutions. Use when enzyme purity and defined activity drive assay or process performance. 8 × USP; Protease ≥200U/mg enzyme powder; Amylase ≥200U/mg enzyme powder; Lipase ≥16U/mg enzyme powder
Accession #
P00761,P00690,P00591
Bioactivity
Protease ≥200U/mg enzyme powder; Amylase ≥200U/mg enzyme powder; Lipase ≥16U/mg enzyme powder
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
100g
P755357-100g
1-2 wks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
$29.90
500g
P755357-500g
1-2 wks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
$69.90
2.5kg
P755357-2.5kg
1-2 wks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
$249.90
Enter a quantity for the sizes you want to add.
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Why this grade

Bioactive,ActiBioPure™,Native,High Performance,EnzymoPure™,8 × USP; Protease ≥200U/mg enzyme powder; Amylase ≥200U/mg enzyme powder; Lipase ≥16U/mg enzyme powder ActiBioPure™,Bioactive,High Performance,Native,EnzymoPure™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at 2-8°C,Protected from light Ships Wet ice Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 170 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Pancreatin is a mixture of several digestive enzymes produced by the exocrine cells of the porcine pancreas. It is a broad-spectrum protease composed of amylase, trypsin, lipase, ribonuclease and protease. It is used for in vitro digestibility analysis. Pancreatin from porcine pancreas has been used to test the sensitivities of cellulolytic bacteria inhibitors.The enzyme has been used along with amyloglucosidase for the in vitro digestion of starch in food samples. Pancreatin from porcine pancreas has been used for in vitro pepsin-pancreatin digestion assays while estimating of lower gut digestibility using rumen feed residues. It has also been used along with pepsin to simulate in vitro gastric and ileal digestion of raw materials in pigs.

Specifications

Product Name
Pancreatin from porcine pancreas, CAS No.8049-47-6
Synonyms
AMY2 | PNLIP | AMY2B | PL | PTL
Grade
ActiBioPure™, Bioactive, High Performance, Native, EnzymoPure™
Specifications & Purity
Bioactive, ActiBioPure™, Native, High Performance, EnzymoPure™, 8 × USP; Protease ≥200U/mg enzyme powder; Amylase ≥200U/mg enzyme powder; Lipase ≥16U/mg enzyme powder
Biochemical and Physiological Mechanisms
Due to the enzymatic components such as trypsin, amylase and lipase, pancreatin hydrolyzes proteins, starch and fats. Pancreatin will convert not less than 25 times its weight of potato starch into soluble carbohydrates in 5 minutes in water at 40 °C, wi
Bioactivity
Protease ≥200U/mg enzyme powder; Amylase ≥200U/mg enzyme powder; Lipase ≥16U/mg enzyme powder
CAS
8049-47-6
Molecule Type
Enzyme
Storage and Shipping
Concentration
8 × USP; Protease ≥200U/mg enzyme powder; Amylase ≥200U/mg enzyme powder; Lipase ≥16U/mg enzyme powder
Reconstitution
Reconstitute in water.
Storage
Store at 2-8°C,Protected from light
Shipped In
Wet ice
Stability And Storage
Store at 2-8℃ long term (18 months). Upon reconstitution, it is recommended to aliquot. Avoid freeze/thaw cycle. Store in the dark.

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

4 results found

Lot NumberCertificate TypeDateItem
ZJ26F0737020Certificate of AnalysisJul 03, 2026 P755357
ZJ26F0737021Certificate of AnalysisJul 03, 2026 P755357
ZJ26F0535338Certificate of AnalysisMay 12, 2026 P755357
ZJ26F0333537Certificate of AnalysisMar 26, 2026 P755357
Documents & Articles
Citations of This Product
References
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14. Xinshuo Wang, Lin Lu, Khizar Hayat, Shuqin Xia.  (2024)  Effect of chickpea thermal treatments on the starch digestibility of the fortified biscuits.  Food Bioscience,      [PMID:] [10.1016/j.fbio.2024.104794]
15. Abdul Mueed, He Ma, Philippe Madjirebaye, Akhtar Ali, Sajjad Ali, Jingwen Yu, Jing Li, Ze-yuan Deng.  (2024)  Effect of flaxseed oil cyclolinopeptides on lipid oxidation, protein oxidation, and lipid profile during in vitro digestion of high-fat beef.  FOOD CHEMISTRY,      [PMID:39305638] [10.1016/j.foodchem.2024.141256]
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18. Zenghong Xing, Wenxin Han, Taotao Dai, Deming Gong, Guowen Zhang.  (2024)  Encapsulation of ferulic acid in potato protein-pectin nanocomplexes with improved stability and controlled release properties.  Food Bioscience,      [PMID:] [10.1016/j.fbio.2024.105553]
19. Xiaoxue Hou, Mengmeng Wang, Tongyuan Hu, Zhinan Wu, Hewei Liang, Yiyi Zhong, Zhihui Ma, Haifeng Zhang, Liang Xiao, Wenjin Zhang, Yuanqiang Zou.  (2025)  Evaluation of the safety and probiotic properties of Limosilactobacillus fermentum BGI-AF16, a uric acid-lowering probiotic strain.  MICROBIAL PATHOGENESIS,      [PMID:39961375] [10.1016/j.micpath.2025.107382]
20. Weijing Wu, Libo Wang, Ju Qiu, Ziyuan Zhuang, Fei Qin, Qianglai Tan, Yanling Wang, Lanlan Wu.  (2024)  Exploring dipeptidyl peptidase-IV inhibitory peptides from Tartary Buckwheat protein: A study of hydrolysis, fractionation, and molecular interactions.  JOURNAL OF FOOD SCIENCE,      [PMID:39617869] [10.1111/1750-3841.17525]
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72. Yujie Li, Jia Wang, Chao Liu, Long Wang, Peng Zhang, Qianyu Zhao, Zhu Xiong, Gaosheng Zhang, Wei Zhang.  (2023)  Remediation of arsenic-contaminated soil using nanoscale schwertmannite synthesized by persulfate oxidation with carboxymethyl cellulose stabilization.  ENVIRONMENTAL RESEARCH,      [PMID:38109958] [10.1016/j.envres.2023.117937]
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133. Xiaodong Ge, Tingting Liu, Yaolin Wang, Huanhuan Wen, Zirui Huang, Ligen Chen, Jianda Xu, Hongcheng Zhou, Qin Wu, Chao Zhao, Rong Shao, Wei Xu.  (2024)  Porous starch microspheres loaded with luteolin exhibit hypoglycemic activities and alter gut microbial communities in type 2 diabetes mellitus mice.  Food & Function,      [PMID:39377562] [10.1039/D4FO02907K]
134. Yuxuan Liu, Qiufang Liang, Ying Liu, Arif Rashid, Abdul Qayum, Jamila A. Tuly, Haile Ma, Song Miao, Xiaofeng Ren.  (2024)  Sodium caseinate/pectin complex-stabilized emulsion: Multi-frequency ultrasound regulation, characterization and its application in quercetin delivery.  FOOD HYDROCOLLOIDS,      [PMID:] [10.1016/j.foodhyd.2024.110316]
135. Huiying Kuang, Xuan Peng, Yixiang Liu, Dan Li.  (2024)  The pro-absorptive effect of glycosylated zein-fatty acid complexes on fucoxanthin via the lipid transporter protein delivery pathway.  FOOD CHEMISTRY,      [PMID:38432136] [10.1016/j.foodchem.2024.138892]
136. Ting Fang, Weihua Zhu, Xiuxia Zhao, Na Gao, Long Huang, Yangyang Liang, Lei Wang, Kai Cui, Wenxuan Lu, Guanjun Hou.  (2025)  Effect of cooking methods on bioaccessibility of trace metal(loid)s in abdominal muscle of red swamp crayfish (Procambarus clarkii) using in vitro gastrointestinal digestion.  LWT-FOOD SCIENCE AND TECHNOLOGY,      [PMID:] [10.1016/j.lwt.2025.118216]
137. Xiaoyu Yang, Miaomiao Jiang, Zongxuan Huang, Hongjian Huang, Hu Zhao, Qinhui Chen, Haiqing Liu.  (2025)  Self-reinforceable poly(lipoic acid)-based tough underwater tissue bioadhesive.  Acta Biomaterialia,      [PMID:40812611] [10.1016/j.actbio.2025.08.024]
138. Fan Xiulei, Wang Shenpeng, Liu Yuhan, Zhang Shu, Wang Wenjie, Ji Wei, Yu Jiazheng, Wang Qian, Lv Bowen.  (2025)  Release of polycyclic aromatic hydrocarbons from tire road wear particles in simulated digestive fluids: release rules and influencing factors.  ENVIRONMENTAL GEOCHEMISTRY AND HEALTH,  47  (10): (1-13).  [PMID:40914921] [10.1007/s10653-025-02715-2]
139. Bowen Xiao, Xiaolei Wang, Jing Yang, Kunkun Wang, Yinqing Zhang, Binbin Sun, Tong Zhang, Lingyan Zhu.  (2020)  Bioaccumulation kinetics and tissue distribution of silver nanoparticles in zebrafish: The mechanisms and influence of natural organic matter.  ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,      [PMID:32171962] [10.1016/j.ecoenv.2020.110454]
140. Chengsheng Jia, Xue Xia, Huiqi Wang, Muhoza Bertrand, Gang Chen, Xiaoming Zhang.  (2020)  Preparation of phytosteryl ornithine ester hydrochloride and improvement of its bioaccessibility and cholesterol-reducing activity in vitro.  FOOD CHEMISTRY,      [PMID:32554308] [10.1016/j.foodchem.2020.127200]
141. Xianling Wei, Ziqing Hu, Weidong Bai, Xiaofang Zeng, Feibai Zhou, Qiangzhong Zhao, Hao Dong, Xiaoyan Liu.  (2025)  Stability and bioaccessibility of lycopene loaded in a Pickering emulsion stabilized by tannic acid–starch complexes: Effect of starch categories.  FOOD RESEARCH INTERNATIONAL,      [PMID:40356170] [10.1016/j.foodres.2025.116392]
142. Tingting Song, Wenyu Wang, Yan Wu, Chaolong Liu, Lu Yuan, Zhihong Sun, Jingjing Zhang, Yong Sun.  (2025)  Functional Liposomes Improve the Oral Absorption of Lurasidone Hydrochloride by Overcoming Multiple Absorption Barriers and Eliminating Food Effect.  International Journal of Nanomedicine,      [PMID:40255673] [10.2147/IJN.S512876]
143. Qing Guo, Min Zhang, Arun S. Mujumdar, Luming Rui.  (2025)  Effects of electric field-assisted freeze-thaw cycle on arrowhead (Sagittaria sagittifolia L.) quality and the structural and physicochemical properties of starch.  Innovative Food Science & Emerging Technologies,      [PMID:] [10.1016/j.ifset.2025.104047]
144. Wen-Xuan Hu, Min Yang, Ping Wang, Jia-Yang Fu, Lin Kang, Xiuzhu Yu, Shuang-kui Du.  (2025)  Influence of extrusion on starch structure, physicochemical properties and in vitro digestibility of banana flour (Musa spp.) and its potential application in wheat dough.  LWT-FOOD SCIENCE AND TECHNOLOGY,      [PMID:] [10.1016/j.lwt.2025.117927]
145. Lingfang Zhang, Qianyi Jiang, Binghua Sun, Xiaoxi Wang, Sen Ma.  (2025)  Designing food matrix structure by adjusting the ratio of soluble/insoluble wheat bran dietary fiber to mitigate the inhibition on wheat protein digestion: Application in noodles.  FOOD CHEMISTRY,      [PMID:40398223] [10.1016/j.foodchem.2025.144773]
146. Chujing Wang, Zengliu Song, Xinyue Ning, Yong Wang, Jie Xiao.  (2025)  Solid Lipid–Threshold Guided Chitosan Coating of NLCs for Improved Gastrointestinal Stability and Curcumin Bioavailability.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,      [PMID:] [10.1016/j.colsurfa.2025.137388]
147. Yuanyuan Li, Xiaoxue Chen, Gongda Wang, Linting Xu, Yichen Liu, Chunlong Yuan, Junjun Li.  (2025)  The release patterns and potential prebiotic characteristics of soluble and insoluble dietary fiber-bound polyphenols from pinot noir grape pomace in vitro digestion and fermentation.  Food Chemistry-X,      [PMID:40642527] [10.1016/j.fochx.2025.102694]
148. Nan Fang, Yan Zeng, Haosheng Huang, Xuemei Yang, Haiqin Leng, Xinyu Chen, Tao Chen, Lijun Zhou, Hongyu Yang, Xiaoyu Jiang, Chunbang Ding, Shiling Feng.  (2025)  Prebiotic potential of Camellia oleifera seed cake polysaccharides revealed by in vitro digestion and fermentation.  LWT-FOOD SCIENCE AND TECHNOLOGY,      [PMID:] [10.1016/j.lwt.2025.118010]
149. Yaqing Lin, Jiabin Wu, Bin Xiong, Lin Wang, Zhikun Zeng, Baodong Zheng, Yi Zhang, Lei Pan.  (2025)  Effect of digestive properties and gut microbiota structure of steam-exploded Laminaria japonica polysaccharide: in vitro dynamic human gastrointestinal systems.  LWT-FOOD SCIENCE AND TECHNOLOGY,      [PMID:] [10.1016/j.lwt.2025.117866]
150. Yuanjie Guo, Jiabao Huang, Yu Luo, Yan Wang, Dan Li, Yixiang Liu.  (2025)  Dual-functional nanoengineered carrier for controlled release and enhanced intestinal translocation: Modulating lipid transporters to boost fucoxanthin anti-obesity efficacy.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:41046894] [10.1016/j.ijbiomac.2025.148091]
151. Yang Tingting, Tao Guanhua, Xu Xinye, Yu Chunyu, Shi Jindou, Ma Qingwen.  (2025)  Phytosterol nanoparticle delivery system based on whey protein-chitosan: enhanced stability, bioavailability, and sustained-release properties.  Journal of Food Measurement and Characterization,      [PMID:] [10.1007/s11694-025-03716-6]
152. Wentao Ma, Wei Liu, Chao Yuan, Bo Cui, Yaqi Liu, Li Guo, Bin Yu, Meng Zhao, Feixue Zou.  (2025)  A double-package delivery system based on κ-carrageenan hydrogels and vitamin E/highly branched cyclic dextrin composites: Structural characteristics and release behavior.  FOOD CHEMISTRY,      [PMID:41308212] [10.1016/j.foodchem.2025.147266]
153. Xin Wang, Shuangjie Qin, Caiwen Wu, Hongbo Li, Hongjuan Li, Jinghua Yu.  (2025)  Effect of adding cream to change the interface composition on the mechanical properties of milk fat globules and system stability.  FOOD CHEMISTRY,      [PMID:41317471] [10.1016/j.foodchem.2025.147304]
154. Weijun Chen, Hui Hou, Jiaxin Han, Xinhui Wang, Yuncheng Li, Fanbing Meng, Donghong Liu, Xiaoying Guo.  (2025)  Conjugation with gum acacia improved the ability of whey protein isolate-(−)-epigallocatechin-3-gallate covalent complexes to stabilize β-carotene emulsions.  Food Chemistry-X,      [PMID:41431723] [10.1016/j.fochx.2025.103339]
155. Yao Huang, Mingmei Shen, Weiyun Zhu, Long Pan.  (2025)  Polyethylene glycol improves in vitro digestibility and fermentability of nutrients for pigs by binding with tannins in sorghum grain.  Italian Journal of Animal Science,      [PMID:] [10.1080/1828051X.2025.2589809]
156. Yu-Ting Huang, Xu Zhang, Xi-Min Ding, Ru-Qin Wu, Shaobo Zhou, Tao Zhou.  (2025)  Antioxidant, hypoglycemic and hypolipidemic activities of pectins from Citrus aurantium ‘Changshanhuyou’.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:41352504] [10.1016/j.ijbiomac.2025.149501]
157. Qing Yang, Shuxian Ding, Qinglong Wang, Li Xu, Xiaoxia Yan, Huan Tang, Langxing Yuan, Xiaoyan Chen, Zhunian Wang, Maoyuan Wang.  (2025)  In Vitro Digestibility, Structural and Functional Properties of Millettia speciosa Champ. Seed Protein.  Biomolecules,  15  (12): (1722).  [PMID:41463375] [10.3390/biom15121722]
158. Yi Shi, Kangkang Zhi, Liping Chen, Yingdong Yang, Yongbing Wang, Ji Zhang.  (2026)  Construction of self-assembled polysaccharide nanoparticles from Lanzhou lily for curcumin delivery: Insights into physicochemical properties and in vitro immunomodulation.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:41500289] [10.1016/j.ijbiomac.2026.150090]
159. Lingfang Zhang, Shuzhen Yang, Xiaojie Qian, Mengyuan Li, Sen Ma, Binghua Sun, Xiaoxi Wang.  (2026)  Non-monotonic effect of starch content on protein digestion in wheat noodles mediated by protein network structural changes.  FOOD RESEARCH INTERNATIONAL,      [PMID:41703872] [10.1016/j.foodres.2026.118418]
160. Hailan Wang, Liyuan Ma, Jiabao Huang, Yu Luo, Yan Wang, Dan Li, Yixiang Liu.  (2026)  Gastrointestinal-controlled dipotassium glycyrrhizinate self-assembly particles enhance fucoxanthin oral bioavailability for improved visual sensitivity.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:41565128] [10.1016/j.ijbiomac.2026.150380]
161. Baozhu Shi, Yueran Ma, Dong Li, Zisheng Luo.  (2026)  Corosolic acid as a dual-function stabilizer in W/O Pickering emulsions enhances its bioaccessibility and α-glucosidase inhibition.  FOOD CHEMISTRY,      [PMID:41616442] [10.1016/j.foodchem.2026.148199]
162. Gerui Ren, Ruiqi Hu, Jiajun Mao, Xinpei Cai, Tianrong Wang, Xin Song, Wentao Wu, Caixin Zhuge, Min Huang, Hujun Xie, Kejun Cheng.  (2026)  From poor solubility to precision delivery: Zein–κ-carrageenan nanovehicles unlock dihydromyricetin's bioactive potential.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:41708022] [10.1016/j.ijbiomac.2026.150961]
163. Juan Tao, Yuning Wei, Mengyu Zhao, Zirong Dong, Zibo Wei, Shuyan Li, Jiaxin Zhao, Jinlong Yang, Jianping Qi.  (2026)  Overcoming mucus trapping by engineering PEGylated self-nanoemulsions for enhanced oral absorption of a novel AMPK activator.  INTERNATIONAL JOURNAL OF PHARMACEUTICS,      [PMID:41740768] [10.1016/j.ijpharm.2026.126704]
164. Junli Lv, Zhilong Ren, Jiali Zou, Nan Wang.  (2026)  Functional properties and bioaccessibility of ferulic acid/β-cyclodextrin inclusion complexes: Molecular dynamics simulation and experimental validation.  Innovative Food Science & Emerging Technologies,      [PMID:] [10.1016/j.ifset.2026.104515]
165. Yue Song, Yutong Chen, Yi Yi, Chenzhi Kan, Fei Lyu, Yangyue Ding, Xuewei Ye, Jianyou Zhang, Gaopeng Zhang.  (2026)  Molecular interactions between guar gum and coix seed endogenous constituents modulating starch digestion kinetics.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:41740908] [10.1016/j.ijbiomac.2026.150783]
166. Yang Yang, Gangjian Guan, Meng Jiao, Yuying Zhang, Meng Dong, Dongmei Li, Xuedi Zhang.  (2026)  Constructing Starch-Based Porous Delivery System to Enhance the Stability and Intestinal Absorption Properties of Brown Algal Polyphenols.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:41734294] [10.1021/acs.jafc.5c14843]
167. Liping Ren, Lingfeng Xu, Xuncai Liu, Yanqun Fan, Chengmei Liu, Xiuting Hu.  (2026)  Increasing the stewing temperature promoted digestion and absorption of edible bird's nest glycoprotein.  JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE,      [PMID:41705343] [10.1002/jsfa.70528]
168. Shen Mingmei, Huang Yao, He Yun, Lyu Yanrong, Zhang Mengyao, Zhu Weiyun, Pan Long.  (2026)  Comparative nutrient digestion and fermentation characteristics of corn and sorghum grain in different segments of the porcine gastrointestinal tract.  JOURNAL OF ANIMAL SCIENCE,      [PMID:] [10.1093/jas/skag097]
169. Zenghong Xing, Xiaoyun Fei, Deming Gong, Guowen Zhang.  (2026)  Ovalbumin-proanthocyanidin‑sodium alginate conjugate-based oleogels: Construction, characterization and resveratrol delivery performance.  FOOD CHEMISTRY,      [PMID:] [10.1016/j.foodchem.2026.149029]
170. Qipeixuan Tian, Yiqi Yang, Yuting Wang, Huanhuan Su, David Everett, Wenle He, Qinzheng Yang, Siru Chen, Yun Zhai, Yuying Fu, Teng Li.  (2026)  Tofu as a Natural Food Delivery System for Curcumin.  ACS Food Science & Technology,      [PMID:] [10.1021/acsfoodscitech.6c00039]
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