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· · COA & SDS available for every product · Same-day shipping on in-stock items 5-BDBD - Moligand™, ≥99%(HPLC) , Antagonist of P2X4, CAS No.768404-03-1, Antagonist of P2X4
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%(HPLC) Synonyms
5-BDBD | HY-101911 | MS-25545 | 5-(3-Bromophenyl)-1,3-dihydro-2H-benzofuro[3,2-e]-1,4-diazepin-2-one | DTXSID30431707 | GTPL9541 | HMS3414A09 | CID 9841560 | NCGC00370894-01 | 5-BDBD, >=98% (HPLC) | PD021674 | HMS3678A09 | SCHEMBL173241 | 5 BDBD;5BDBD | B
Shipped In
Ice chest + Ice pads
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Why this grade Moligand™, ≥99%(HPLC) Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 1 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Synonyms
5-BDBD | HY-101911 | MS-25545 | 5-(3-Bromophenyl)-1, 3-dihydro-2H-benzofuro[3, 2-e]-1, 4-diazepin-2-one | DTXSID30431707 | GTPL9541 | HMS3414A09 | CID 9841560 | NCGC00370894-01 | 5-BDBD, >=98% (HPLC) | PD021674 | HMS3678A09 | SCHEMBL173241 | 5 BDBD;5BDBD | B
Specifications & Purity
Moligand™, ≥99%(HPLC)
Biochemical and Physiological Mechanisms
Potent and selective P2X4receptor antagonist. Blocks P2X4-mediated currents in Chinese hamster ovary cells (IC50= 0.50μM). Exhibits no significant antagonist effects at other P2X receptors. Reduces long-term potentiation (LTP) in rat hippocampal slices.
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Mechanism of action
Antagonist of P2X4
Names and Identifiers Pubchem Sid 488196355 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/488196355 Canonical Smiles C1C(=O)NC2=C(C(=N1)C3=CC(=CC=C3)Br)OC4=CC=CC=C42 IUPAC Name 5-(3-bromophenyl)-1,3-dihydro-[1]benzofuro[3,2-e][1,4]diazepin-2-one InChIKey NKYMVQPXXTZHSF-UHFFFAOYSA-N INCHI 1S/C17H11BrN2O2/c18-11-5-3-4-10(8-11)15-17-16(20-14(21)9-19-15)12-6-1-2-7-13(12)22-17/h1-8H,9H2,(H,20,21) Isomeric SMILES C1C(=O)NC2=C(C(=N1)C3=CC(=CC=C3)Br)OC4=CC=CC=C42 Alternate CAS 768404-03-1 MeSH Entry Terms 5-(3-bromophenyl)-1,3-dihydro-2H-benzofuro(3,2-e)-1,4-diazepin-2-one;5-BDBD compound Molecular Weight 355.19 Reaxy-Rn 12476564 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=12476564&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organic acids and derivatives Class Carboxylic acids and derivatives Subclass Amino acids, peptides, and analogues Intermediate Tree Nodes Amino acids and derivatives Direct Parent Alpha amino acids and derivatives Alternative Parents Benzofurans Bromobenzenes Aryl bromides Heteroaromatic compounds Furans Secondary carboxylic acid amides Lactams Ketimines Propargyl-type 1,3-dipolar organic compounds Oxacyclic compounds Azacyclic compounds Organobromides Organic oxides Hydrocarbon derivatives Carbonyl compounds Molecular Framework Aromatic heteropolycyclic compounds Substituents Alpha-amino acid or derivatives - Benzofuran - Halobenzene - Bromobenzene - Aryl bromide - Aryl halide - Monocyclic benzene moiety - Benzenoid - Heteroaromatic compound - Furan - Ketimine - Lactam - Carboxamide group - Secondary carboxylic acid amide - Propargyl-type 1,3-dipolar organic compound - Organic 1,3-dipolar compound - Organoheterocyclic compound - Azacycle - Oxacycle - Organic nitrogen compound - Imine - Organohalogen compound - Organobromide - Carbonyl group - Organonitrogen compound - Organooxygen compound - Hydrocarbon derivative - Organic oxide - Organic oxygen compound - Aromatic heteropolycyclic compound Description This compound belongs to the class of organic compounds known as alpha amino acids and derivatives. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon), or a derivative thereof. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 35.52, Max Conc. mM: 100 Molecular Weight 355.200 g/mol XLogP3 3.800 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 3 Rotatable Bond Count 1 Exact Mass 354 Da Monoisotopic Mass 354 Da Topological Polar Surface Area 54.600 Ų Heavy Atom Count 22 Formal Charge 0 Complexity 481.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
Citations of This Product References 1. Zejin Liu, Mengyang Sun, Wenhua Liu, Fangyu Feng, Xinyu Li, Chaolei Jin, Yijie Zhang, Junpeng Wang. (2024) Deficiency of purinergic P2X4 receptor alleviates experimental autoimmune hepatitis in mice. BIOCHEMICAL PHARMACOLOGY, [PMID:38301964 ] [10.1016/j.bcp.2024.116033 ]
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