AQC - ≥95% , CAS No.148757-94-2

CAS: 148757-94-2 Cat. No.: A131410 Molecular Weight: 285.25

GRADE & PURITY ≥95%

Synonyms

6-aminoquinolyl-n-hydroxysuccinimidyl carbamate | AQC | 2,5-Dioxo-1-pyrrolidinyl 6-Quinolylcarbamate | 2,5-dioxopyrrolidin-1-yl N-(quinolin-6-yl)carbamate | 2,5-Dioxopyrrolidin-1-yl quinolin-6-ylcarbamate | (2,5-dioxopyrrolidin-1-yl) N-quinolin-6-ylcarbam

Storage

Protected from light,Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Overview

AQC is used in analysis of amino acids or protein sequence by HPLC with fluorescence detection.
A useful chemical for amino acid and protein detection.

Specifications

Synonyms

6-aminoquinolyl-n-hydroxysuccinimidyl carbamate | AQC | 2, 5-Dioxo-1-pyrrolidinyl 6-Quinolylcarbamate | 2, 5-dioxopyrrolidin-1-yl N-(quinolin-6-yl)carbamate | 2, 5-Dioxopyrrolidin-1-yl quinolin-6-ylcarbamate | (2, 5-dioxopyrrolidin-1-yl) N-quinolin-6-ylcarbam

Specifications & Purity

≥95%

Biochemical and Physiological Mechanisms

Reagent suitable for amino acid or protein sequence analysis by HPLC with fluorescence detection.

Storage

Protected from light, Store at -20°C, Argon charged

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Note

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Purity

≥95%

Names and Identifiers

• Pubchem Sid: 488193289
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488193289
• Canonical Smiles: C1CC(=O)N(C1=O)OC(=O)NC2=CC3=C(C=C2)N=CC=C3
• IUPAC Name: (2,5-dioxopyrrolidin-1-yl) N-quinolin-6-ylcarbamate
• InChIKey: LINZYZMEBMKKIT-UHFFFAOYSA-N
• INCHI: 1S/C14H11N3O4/c18-12-5-6-13(19)17(12)21-14(20)16-10-3-4-11-9(8-10)2-1-7-15-11/h1-4,7-8H,5-6H2,(H,16,20)
• Isomeric SMILES: C1CC(=O)N(C1=O)OC(=O)NC2=CC3=C(C=C2)N=CC=C3
• Molecular Weight: 285.25
• Reaxy-Rn: 22364583
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=22364583&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Class Quinolines and derivatives

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Class: Quinolines and derivatives
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Quinolines and derivatives
• Alternative Parents: Pyrrolidine-2-ones Pyridines and derivatives Benzenoids Heteroaromatic compounds Dicarboximides Organic carbonic acids and derivatives Lactams Azacyclic compounds Organopnictogen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Quinoline - Pyridine - Pyrrolidone - 2-pyrrolidone - Benzenoid - Dicarboximide - Pyrrolidine - Heteroaromatic compound - Carbonic acid derivative - Lactam - Azacycle - Carboxylic acid derivative - Organic oxide - Organopnictogen compound - Organic oxygen compound - Carbonyl group - Organic nitrogen compound - Organooxygen compound - Organonitrogen compound - Hydrocarbon derivative - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as quinolines and derivatives. These are compounds containing a quinoline moiety, which consists of a benzene ring fused to a pyrimidine ring to form benzo[b]azabenzene.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: DMSO : 100 mg/mL (350.57 mM; Need ultrasonic)；
• Sensitivity: Hygroscopic；Light sensitive;Moisture sensitive
• Molecular Weight: 285.250 g/mol
• XLogP3: 1.100
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 3
• Exact Mass: 285.075 Da
• Monoisotopic Mass: 285.075 Da
• Topological Polar Surface Area: 88.600 Ų
• Heavy Atom Count: 21
• Formal Charge: 0
• Complexity: 438.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

1. Chun Qu, Chaohui Jian, Kun Ge, Dan Zheng, Yuqian Bao, Wei Jia, Aihua Zhao.  (2022)  A rapid UHPLC-QDa method for quantification of human salivary amino acid profiles.  JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES,      [PMID:36274351] [10.1016/j.jchromb.2022.123485]

2. Meng Tao, Shanshan Wang, Sixu Li, Anan Xu, Zhen Tu, Yanyan Cao, Zhengquan Liu.  (2025)  Identification and quantification of alkyloxazoles in roasted tea infusion (Camellia sinensis): Their thresholds, sensory impact, and related amino acids.  FOOD CHEMISTRY,      [PMID:40056624] [10.1016/j.foodchem.2025.143735]

3. Weiwei Wu, Yanming Tuo, Zhihui Wang, Na Chen, Yuxue Jiang, Chuanjiu Wu, Yongquan Xu, Wen Zeng, Weijiang Sun.  (2026)  Comprehensive analysis of taste variations and pleasantness components in white tea from different organs of Camellia sinensis cv. Fuding Dabaicha.  FOOD CHEMISTRY,      [PMID:41702009] [10.1016/j.foodchem.2026.148437]