Arbutin - 10mM in DMSO , CAS No.497-76-7

CAS: 497-76-7 Cat. No.: A409174 Formula: C12H16O7 Molecular Weight: 272.25 Beilstein Registry Number: 89673 EC Number: 207-850-3
AVAILABLE TO ORDER
GRADE & PURITY 10mM in DMSO
Synonyms
Uva,p-Arbutin, β-Arbutin | β-D-Glucopyranoside, 4-hydroxyphenyl
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
★
Size
USA
Germany (EU)*
Price
Qty
1ml
A409174-1ml
2 In stock
—
$47.90
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Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 30 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Information

Arbutin Arbutin (Uva, p-Arbutin, β-Arbutin) is a tyrosinase inhibitor with IC50 of 0.9 mM and 0.7 mM for Monophenolase and Diphenolase, respectively.
In vitro


In vivo


Cell Data

cell lines:

Concentrations:

Incubation Time:

Powder Purity:≥99%

Specifications

Synonyms
Uva,p-Arbutin, β-Arbutin | β-D-Glucopyranoside, 4-hydroxyphenyl
Specifications & Purity
10mM in DMSO
Biochemical and Physiological Mechanisms
Arbutin (Uva, p-Arbutin, β-Arbutin) is a tyrosinase inhibitor with IC50 of 0.9 mM and 0.7 mM for Monophenolase and Diphenolase, respectively.
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Product Properties
ALogP
-0.7
Names and Identifiers
Isomeric SMILES
C1=CC(=CC=C1O)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O
WGK Germany
3
Molecular Weight
272.25
Beilstein
89673
Reaxy-Rn
22933063
Reaxys-RN_link_address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=22933063&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
SolubilitySolubility (25°C) In vitro DMSO: 36 mg/mL (40.76 mM); Water: Insoluble; Ethanol: Insoluble;
Specific Rotation[α]-65.5 ° (C=4, H2O)
Melt Point(°C)198°C
Documents & Articles
Tyrosinase: a key regulatory enzyme in melanin synthesis and its biological and applied significance
Mechanistic Analysis of Topical Glutathione in Skincare: Cellular Redox Regulation, Skin Delivery Challenges, and SLN-Based Delivery Strategies
Mechanism of Kojic Acid in Reducing Hyperpigmentation: From Tyrosinase Inhibition to Melanin Production Regulation
Analysis of Hydrolyzed Pearl as a Cosmetic Raw Material: Preparation Process, Active Components, and Skincare Formulation Applications
The Dual-Targeted Skin-Brightening Mechanism of 4-MSK: Inhibiting Melanin Production and Reducing Epidermal Pigment Retention
Phenylethyl Resorcinol (377): Structural Characteristics, Melanogenesis-Regulating Mechanisms, and Related Applications in Formulation Research
Mechanism of Action of Tranexamic Acid in Pigmentation Care: From the Plasmin System to Regulation of Inflammation-Driven Pro-Melanogenic Signaling
Reactions and Applications of 3,3-Difluoroallyl Sulfonium Salts (DFASs): Small-Molecule gem-Difluoroallylation, Selective Peptide Modification, and Subsequent Functionalization
How Arbutin Regulates Melanin Production: α/β Anomeric Configuration and Tyrosinase Action
Glycosidic Bond Structure and Cleavage Mechanisms—Chemical and Enzymatic Cleavage of O-, N-, S-, and C-Glycosides
Citations of This Product
Solution Calculators
Reviews

Customer Reviews

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