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darizmetinib - Moligand™, ≥98% , Inhibitor of mitogen-activated protein kinase kinase 4, CAS No.2369583-33-3, Inhibitor of mitogen-activated protein kinase kinase 4

darizmetinib - Moligand™, ≥98% , Inhibitor of mitogen-activated protein kinase kinase 4, CAS No.2369583-33-3, Inhibitor of mitogen-activated protein kinase kinase 4

CAS: 2369583-33-3 Cat. No.: D609742 Molecular Weight: 457.45 PubChem CID: 139369660

COA

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darizmetinib - Moligand™, ≥98% CAS No(2369583-33-3) by Aladdin Scientific

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AVAILABLE TO ORDER

GRADE & PURITY Moligand™ ? ≥98%

Synonyms

HY-152860 | 1-Propanesulfonamide, N-[2,6-difluoro-3-[[5-(4-pyridinyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]carbonyl]phenyl]- | Darizmetinib

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview Specifications Names and Identifiers Documentation Advanced Data 3D Structure Associated Targets(Human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Solution Calculators Reviews

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Why this grade

Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Darizmetinib is an inhibitor of mitogen-activated protein kinase kinase (MAP2K).

Specifications

Synonyms

HY-152860 | 1-Propanesulfonamide, N-[2, 6-difluoro-3-[[5-(4-pyridinyl)-1H-pyrazolo[3, 4-b]pyridin-3-yl]carbonyl]phenyl]- | Darizmetinib

Specifications & Purity

Moligand™, ≥98%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Action Type

INHIBITOR

Mechanism of action

Inhibitor of mitogen-activated protein kinase kinase 4

Purity

≥98%

Names and Identifiers

Canonical Smiles	CCCS(=O)(=O)Nc1c(ccc(c1F)C(=O)c1c2cc(cnc2n[nH]1)c1ccncc1)F
IUPAC Name	N-[2,6-difluoro-3-(5-pyridin-4-yl-2H-pyrazolo[3,4-b]pyridine-3-carbonyl)phenyl]propane-1-sulfonamide
InChIKey	WBNMARNYIFMNEP-UHFFFAOYSA-N
INCHI	1S/C21H17F2N5O3S/c1-2-9-32(30,31)28-19-16(22)4-3-14(17(19)23)20(29)18-15-10-13(11-25-21(15)27-26-18)12-5-7-24-8-6-12/h3-8,10-11,28H,2,9H2,1H3,(H,25,26,27)
Isomeric SMILES	CCCS(=O)(=O)NC1=C(C=CC(=C1F)C(=O)C2=C3C=C(C=NC3=NN2)C4=CC=NC=C4)F
PubChem CID	139369660
Molecular Weight	457.45

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

3D Structure

Associated Targets(Human)

MAP2K4 Tchem Dual specificity mitogen-activated protein kinase kinase 4 (0 Activities)

Discover Target: MAP2K4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MAP2K4 Tchem Dual specificity mitogen-activated protein kinase kinase 4 (1051 Activities)

Discover Target: MAP2K4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

8 results found

Lot Number	Certificate Type	Date	Item
I2420510	Certificate of Analysis	Sep 11, 2024	D609742
I2420511	Certificate of Analysis	Sep 11, 2024	D609742
I2420512	Certificate of Analysis	Sep 11, 2024	D609742
I2420513	Certificate of Analysis	Sep 11, 2024	D609742
I2420514	Certificate of Analysis	Sep 11, 2024	D609742
I2420515	Certificate of Analysis	Sep 11, 2024	D609742
I2420516	Certificate of Analysis	Sep 11, 2024	D609742
I2420517	Certificate of Analysis	Sep 11, 2024	D609742

Solution Calculators

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Reviews

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