DL-Norepinephrine Hydrochloride - 10mM in DMSO , CAS No.55-27-6

CAS: 55-27-6 Cat. No.: D424709 Molecular Weight: 205.64 Beilstein Registry Number: 3707003 EC Number: 200-229-8
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GRADE & PURITY 10mM in DMSO
Synonyms
1,2-BENZENEDIOL, 4-(2-AMINO-1-HYDROXYETHYL)-, HYDROCHLORIDE, (+/-)- | FT-0673074 | DL-alpha-(Aminomethyl)-3,4-dihydroxybenzyl alcohol | EINECS 200-229-8 | Levarterenol hydrochloride; L-Noradrenaline hydrochloride | EN300-1590673 | NORADRENALINE HYDROCHLOR
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
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Size
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Price
Qty
1ml
D424709-1ml
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Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 7 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Norepinephrine modulates human dendritic cell activation by altering cytokine release
It is suitable adrenergic drug used in the following studies:To investigate the effects of adrenergic drugs on lantern of larval fly; To evaluate the ability of α-adrenergic stimulation in the presence of elevated calcium levels to induce delayed after depolarizations and triggered activity in Purkinje fibers isolated from cat hearts; Simultaneous reduction and surface functionalization of graphene oxide by a one-step poly(norepinephrine) functionalization.

Specifications

Synonyms
1, 2-BENZENEDIOL, 4-(2-AMINO-1-HYDROXYETHYL)-, HYDROCHLORIDE, (+/-)- | FT-0673074 | DL-alpha-(Aminomethyl)-3, 4-dihydroxybenzyl alcohol | EINECS 200-229-8 | Levarterenol hydrochloride; L-Noradrenaline hydrochloride | EN300-1590673 | NORADRENALINE HYDROCHLOR
Specifications & Purity
10mM in DMSO
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
MODULATOR
Names and Identifiers
Canonical SmilesC1=CC(=C(C=C1C(CN)O)O)O.Cl
IUPAC Name4-(2-amino-1-hydroxyethyl)benzene-1,2-diol;hydrochloride
InChIKeyFQTFHMSZCSUVEU-UHFFFAOYSA-N
INCHI1S/C8H11NO3.ClH/c9-4-8(12)5-1-2-6(10)7(11)3-5;/h1-3,8,10-12H,4,9H2;1H
Isomeric SMILES C1=CC(=C(C=C1C(CN)O)O)O.Cl
WGK Germany 3
RTECS DN6650000
Molecular Weight 205.64
Beilstein 3707003
Reaxy-Rn 4211089
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4211089&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

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✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

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📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

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Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClassPhenols
SubclassBenzenediols
Intermediate Tree Nodes Not available
Direct ParentCatechols
Alternative Parents Aralkylamines  1-hydroxy-4-unsubstituted benzenoids  1-hydroxy-2-unsubstituted benzenoids  Benzene and substituted derivatives  Secondary alcohols  1,2-aminoalcohols  Organopnictogen compounds  Monoalkylamines  Hydrochlorides  Hydrocarbon derivatives  Aromatic alcohols  
Molecular FrameworkAromatic homomonocyclic compounds
Substituents Catechol - 1-hydroxy-4-unsubstituted benzenoid - 1-hydroxy-2-unsubstituted benzenoid - Aralkylamine - Monocyclic benzene moiety - 1,2-aminoalcohol - Secondary alcohol - Organopnictogen compound - Aromatic alcohol - Alcohol - Primary amine - Organooxygen compound - Organonitrogen compound - Primary aliphatic amine - Organic oxygen compound - Organic nitrogen compound - Amine - Hydrochloride - Hydrocarbon derivative - Aromatic homomonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as catechols. These are compounds containing a 1,2-benzenediol moiety.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
GLP1R Tclin Glucagon-like peptide 1 receptor (111429 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
POLK Tbio DNA polymerase kappa (8653 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
POLI Tchem DNA polymerase iota (116820 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
POLH Tchem DNA polymerase eta (21678 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM4A Tchem Lysine-specific demethylase 4A (52245 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Pseudomonas aeruginosa (123386 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Klebsiella pneumoniae (43867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Acinetobacter baumannii (41033 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Escherichia coli (133304 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cryptococcus neoformans (21258 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Candida albicans (78123 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Phosphoglycerate kinase, glycosomal (2184 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

1 results found

Lot NumberCertificate TypeDateItem
J2210009Certificate of AnalysisMay 13, 2026 D424709
Chemical and Physical Properties
Molecular Weight205.640 g/mol
XLogP3
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count4
Rotatable Bond Count2
Exact Mass205.051 Da
Monoisotopic Mass205.051 Da
Topological Polar Surface Area86.700 Ų
Heavy Atom Count13
Formal Charge0
Complexity142.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count2
Documents & Articles
Citations of This Product
References
1. Man Zhang, Rubo Tian, Siyang Tang, Kejing Wu, Binshen Wang, Yingying Liu, Yingming Zhu, Houfang Lu, Bin Liang.  (2023)  The structure and properties of lignin isolated from various lignocellulosic biomass by different treatment processes.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:37285885] [10.1016/j.ijbiomac.2023.125219]
2. Wei Luo, Teris A. van Beek, Bo Chen, Han Zuilhof, Gert IJ. Salentijn.  (2022)  Boronate affinity paper spray mass spectrometry for determination of elevated levels of catecholamines in urine.  ANALYTICA CHIMICA ACTA,      [PMID:36368818] [10.1016/j.aca.2022.340508]
3. Tian Wang, Boya Hao, Shilin Xu, Jie Meng, Tao Wen, Jian Liu, Haiyan Xu.  (2022)  Effective RNAi in leukemia cells is enhanced by spermine-modified pullulan combined with desloratadine.  CARBOHYDRATE POLYMERS,      [PMID:35725203] [10.1016/j.carbpol.2022.119646]
4. He Maofang, Wei Yinmao, Wang Rong, Wang Chunyang, Zhang Bo, Han Lu.  (2019)  Boronate affinity magnetic nanoparticles with hyperbranched polymer brushes for the adsorption of cis-diol biomolecules.  MICROCHIMICA ACTA,  186  (10): (1-9).  [PMID:31529296] [10.1007/s00604-019-3785-y]
5. Lingsha Cheng, Haoqian Wu, Xiaoying Cai, Youying Zhang, Siqi Yu, Yuanlong Hou, Zhe Yin, Qingyuan Yan, Qiong Wang, Taipeng Sun, Guangji Wang, Yonggui Yuan, Xueli Zhang, Haiping Hao, Xiao Zheng.  (2024)  A Gpr35-tuned gut microbe-brain metabolic axis regulates depressive-like behavior.  Cell Host & Microbe,      [PMID:38198925] [10.1016/j.chom.2023.12.009]
6. Wei Wei, Yali Liu, Yuanlong Hou, Shuqi Cao, Zhuo Chen, Youying Zhang, Xiaoying Cai, Qingyuan Yan, Ziguang Li, Yonggui Yuan, Guangji Wang, Xiao Zheng, Haiping Hao.  (2024)  Psychological stress-induced microbial metabolite indole-3-acetate disrupts intestinal cell lineage commitment.  Cell Metabolism,      [PMID:38266651] [10.1016/j.cmet.2023.12.026]
7. Yushuang Guo, Mingli Chen, Ting Yang, Jianhua Wang.  (2023)  Ratio-Metric Fluorescence/Colorimetric and Smartphone-Assisted Visualization for the Detection of Dopamine Based on Cu-MOF with Catecholase-like Activity.  Chemosensors,  11  (8): (431).  [PMID:] [10.3390/chemosensors11080431]
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