DOTA-bis(tert-butyl)ester - ≥97% , CAS No.913542-71-9

CAS: 913542-71-9 Cat. No.: D1423986 Molecular Weight: 516.63

GRADE & PURITY ≥97%

Synonyms

2,2'-(4,10-Bis(2-(tert-butoxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,7-diyl)diacetic acid | DOTA di(tBu)ester

Storage

Store at 2-8°C,Argon charged

Shipped In

Wet ice

Overview

DOTA-bis(tert-butyl)ester is a DOTA-based metal chelator that can bind to radionuclides and is used to prepare radionuclide conjugates (RDCs). DOTA-bis(tert-butyl)ester can be conjugated with different salts to form different metal chelators, such as hydrochloride to obtain DOTA-MN2. DOTA-MN2 can be reacted with [67]Ga-citrate to obtain radiolabeling. When (67)Ga-DOTA-MN2 is incubated in phosphate buffer solution or mouse plasma for 24 hours, it does not undergo significant decomposition. In the biodistribution experiment of NFSa tumor mice, it has high tumor uptake and rapid plasma clearance, and is a good material for SPECT and PET studies.

Specifications

Synonyms

2, 2'-(4, 10-Bis(2-(tert-butoxy)-2-oxoethyl)-1, 4, 7, 10-tetraazacyclododecane-1, 7-diyl)diacetic acid | DOTA di(tBu)ester

Specifications & Purity

≥97%

Storage

Store at 2-8°C, Argon charged

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥97%

Names and Identifiers

• Molecular Weight: 516.63