Laboratory Protocols & SOPs Library
- Tests for syrup preparations SummarySyrup (Appendix I K of Part II of the 2010 edition of the Chinese Pharmacopoeia) refers to a concentrated aqueous sucrose solution containing the drug for oral administration. The quality requirements for syrup, in addition to clarification, the amount of sucrose should not be less than ...
- Applying, coating, filming agent inspection test SummaryApplication (Appendix I T of Part II of the 2010 edition of the Chinese Pharmacopoeia) refers to liquid preparations containing a solution, emulsion or suspension of a drug in ethanol, oil or a suitable solvent for rubbing on unbroken skin. Spread (Appendix I T of Part II of the 2010 ...
- Membrane agent inspection test SummaryMembrane (Appendix I M of the 2010 edition of the Chinese Pharmacopoeia, Part II) refers to the membrane preparation made by processing the drug and suitable film-forming materials. It is used for oral administration or mucous membrane. For the quality requirements of film preparation, in ...
- Detergents, rinses, and enemas screening tests SummaryLotion (Chinese Pharmacopoeia, 2010 Edition, Part II, Appendix I S) means a solution, emulsion, or suspension containing a drug for cleansing or applying to unbroken skin. Flushing agent (Chinese Pharmacopoeia, 2010 Edition, Part II, Appendix 1 S) means a sterile solution for flushing ...
- Experimental effects of sodium phenobarbital and actinomycin D on cytochrome P-450 content in mouse liver SummaryP-450 belongs to hemoglobin protein, and its reduced form combines with CO and shows an absorption peak at 450 nm. Therefore, the content of P-450 can be determined by the method of oscillometric spectrometry. After passing CO through the liver homogenate samples, the reducing agent ...
- Experimental prevention of barium chloride-induced arrhythmias by propranolol and quinidine SummaryBarium chloride induces arrhythmias by increasing the inward Na+ current in Purkinje fibers and increasing the depolarization rate of the maximal diastolic potential. The purpose of this experiment was to observe the preventive effect of propranolol and quinidine on barium ...
- Experiments on the relationship between solubility and action of barium salts SummarySolubility-action relationship experiments with barium salts can be used to study the effect of the physicochemical properties of a drug on its action.Operation methodcomparative lawPrincipleCommon barium salts include barium sulfate, barium carbonate, barium chloride, barium sulfide, ...
- Experimental action of prazosin on isolated vascular smooth muscle SummaryThe rabbit isolated aortic strip assay can be used to observe the effects of drugs on the diastolic and contractile functions of vascular smooth muscle. Observation of the effects of drugs on aortic strips treated by hyperkalemic depolarization and norepinephrine allows a preliminary ...
- Experiments on the effect of different routes of administration on drug action SummaryIn pharmacology experiments, there are many factors affecting the experimental results, some of which can be controlled, while some are difficult to control. In order to reduce the influence of multi-factors and difficult-to-control factors, a control group should be set up at the same ...