In recent years, asymmetric organic catalytic processes have increasingly become more mature and have been utilized in practical application scenarios.In comparison to metal catalytic processes, organic amine catalysts present numerous potential advantages, such as a more stable physicochemical ...
Asymmetric organocatalysis has emerged as a powerful synthetic tool that is complementary to metal-catalyzed reactions. Pioneering work in this area dates back to the 1970s in which Eder et al. and Hajos et al. separately reported an intramolecular asymmetric aldol reaction which employed ...
Since the first proline-catalyzed asymmetric synthesis was reported in 1971, a number of asymmetric syntheses using proline and derivatives have been developed. Proline-type organocatalysts are predominantly applicable to a wide assortment of asymmetric aldol reactions and asymmetric ...
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