The BAFF pathway and the PD-1 pathway represent two typical directions in immune regulation by therapeutic monoclonal antibodies. The BAFF pathway mainly regulates B-cell survival, maturation, and autoantibody production, making it suitable for studies related to autoimmunity and abnormal ...
The APRIL pathway is an important component of the BAFF/APRIL humoral immune regulatory system. Its functional focus is centered on plasma cell survival, maintenance of antibody production, immunoglobulin class switching, and regulation of mucosal humoral immunity. Compared with BAFF, which more ...
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