Topic

C-H Functionalization

Techniques for detecting, quantifying and localizing antigens and antibodies — ELISA, Western blotting, immunohistochemistry and flow cytometry. Below are the protocols, FAQs and technical articles in our knowledge base tagged with this topic.

13 resources · protocols, FAQs & articles
article

2,3-Dichloro-5,6-Dicyanobenzoquinone, DDQ

DDQ (2,3-dichloro-5,6-dicyanobenzoquinone), which exhibits stronger oxidizing properties than 1,4-benzoquinone, serves as a reagent in oxidative coupling and cyclization reactions, as well as in the dehydrogenation of hydroaromatic compounds.

Updated Jun 202512 min read✓ Reviewed
article

White Catalyst

The "White catalyst", developed by Professor M. Christina White and her team at the University of Illinois-Urbana, has proven to be an outstanding catalyst for the functionalization of allylic carbon centers.

Updated Jun 202512 min read✓ Reviewed
article

Electrochemical Allylic C-H Oxidation with N-Hydroxytetrachlorophthalimide (TCNHPI)

Professor Phil Baran and his team have created a new reagent called N-Hydroxytetrachlorophthalimide (H401609), which offers a cost-effective, scalable, and safe alternative for commonly used chemical transformations such as allylic oxidations, as well as Negishi and Suzuki-Miyaura cross-coupling ...

Updated Jun 202512 min read✓ Reviewed
article

Diversinates™: Any-Stage Functionalization of (Hetero)aromatic Scaffolds

The core of the chemical industry revolves around the synthesis of heteroaromatic and aromatic compounds. Given the escalating demand for novel chemical entities amidst dwindling resources and tight timelines imposed on research projects, there is a pressing need for a swift method to diversify ...

Updated Jun 202512 min read✓ Reviewed
article

MCAT-53™ Catalyst for Ruthenium Formation

MCAT-53™, a novel ruthenium catalyst, simplifies C-H activated C-C coupling in water by eliminating extra steps and avoiding solvents like NMP.

Updated Jun 202512 min read✓ Reviewed
article

Jørgensen’s Organocatalysts

Professor Karl Anker Jørgensen and his research team have synthesized (R)- and (S)-α,α-bis[3,5-bis(trifluoromethyl)phenyl]-2-pyrrolidinemethanol trimethylsilyl ether compounds, which excel as chiral organocatalysts for the direct and asymmetric α-functionalization process of aldehydes.

Updated Jun 202512 min read✓ Reviewed
article

C–H Amination

The Du Bois group at Stanford University has achieved significant advancements in Rh-catalyzed C–H amination through oxidative cyclization of carbamate, sulfamate, sulfamide, urea, and guanidine substrates. This methodology produces 1,2- and 1,3-heteroatom motifs masked within 5- and ...

Updated Jun 202512 min read✓ Reviewed
article

N-Bromosuccinimide (NBS)

N-Bromosuccinimide (NBS) is a brominating and oxidizing agent that is used as source for bromine in radical reactions (for example: allylic brominations) and various electrophilic additions. The NBS bromination of substrates such as alcohols and amines, followed by elimination of HBr in the ...

Updated Jun 202512 min read✓ Reviewed
article

Trimethylamine borane / Borane trimethylamine complex

Trimethylamine borane, also known as trimethylamine complex with borane or trimethylamine borane adduct, is a chemical compound with the formula (CH3)3N·BH3. It is a coordination complex formed by the reaction between trimethylamine (N(CH3)3) and borane (BH3).

Updated Jun 202512 min read✓ Reviewed
article

Boranes (Dimethylsulfide Borane, Borane-Tetrahydrofuran Complex)

Diborane (B2H6), the simplest borane, is a useful reagent with many applications, but it is pyrophoric, gaseous and not convenient to handle. There is a wide range of boranes: Decaborane for example is not as reactive as diborane and is used as reducing agent too.

Updated Jun 202512 min read✓ Reviewed
article

Bis(pinacolato)diboron, B2pin2

Bis(pinacolato)diboron is a covalent compound containing two boron atoms and two pinacolato ligands. It has the formula [(CH3)4C2O2B]2; the pinacol groups are sometimes abbreviated as "pin", so the structure is sometimes represented as B2pin2. It is a colourless solid that is soluble in organic ...

Updated Jun 202512 min read✓ Reviewed
article

Benzoyl Peroxide (BPO)

Benzoyl peroxide is a chemical compound with structural formula (C6H5−C(=O)O−)2, often abbreviated as (BzO)2. In terms of its structure, the molecule can be described as two benzoyl (C6H5−C(=O)−, Bz) groups connected by a peroxide (−O−O−). It is a white granular solid with a faint ...

Updated Jun 202512 min read✓ Reviewed

Related topics

Techniques often explored alongside immunological experiments.

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.