RNA-DNA hybrids are nucleic acid structures formed by pairing between an RNA strand and a DNA template strand. Typical forms include transcription-associated R-loops and hybrid regions formed after ribonucleotides are incorporated into DNA. RNase H1, RNase H2, helicases, topoisomerases, and ...
The cell cycle is an ordered process through which cells complete DNA replication, chromosome segregation, and cell division. The DNA damage response (DDR) is responsible for pausing the cell cycle and initiating repair when replication errors, DNA breaks, or replication stress occur.
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