Topic: Hybrid bifunctional small molecule compound

Articles by Topic "Hybrid bifunctional small molecule compound"

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  1. Three Key Components of PROTAC Design: E3 Ligase Ligands, Linkers, and Target Protein Ligands (with an Aladdin Reagent Selection Guide) PROTACs (PROteolysis-TArgeting Chimeras) are heterobifunctional small molecules that induce targeted protein degradation. Each PROTAC molecule contains two distinct ligands: one is a target protein ligand that binds specifically to the intracellular protein of interest (POI), and the other is a ...
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