Articles by Topic "N-Haloalkyl Phthalimides"

1. Experimental Decision-Making for Introducing Aminoalkyl Side Chains Using N-Haloalkyl Phthalimides: Chain Length, Leaving Group, and Deprotection Choice
   posted this at Apr 21, 2026

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   Such intermediates are commonly used to introduce an amino side chain into a target scaffold in protected form first, and then release the corresponding primary amine in a later step by hydrolysis or hydrazinolysis. This is the basic strategy established by the Gabriel synthesis: formation of an ...