10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 4 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Information
Gramine (Donaxine) is a natural indole alkaloid isolated from giant reed, acts as an active adiponectin receptor (AdipoR) agonist, with IC50 of 3.2 µM and 4.2 µM for AdipoR2 and AdipoR1, respectively. Gramine is also a human and mouse β2-Adrenergic recept
In vitro
In vivo
Cell Data
cell lines：
Concentrations：
Incubation Time：
Powder Purity:≥97%
| Isomeric SMILES | CN(C)CC1=CNC2=CC=CC=C21 |
|---|---|
| WGK Germany | 3 |
| RTECS | NL7525000 |
| Molecular Weight | 174.24 |
| Beilstein | 140521 |
| Reaxy-Rn | 140521 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=140521&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Solubility | Solubility (25°C) In vitro Ethanol: mg/mL |
|---|---|
| Flash Point(°F) | 167℃ |
| Flash Point(°C) | 167℃ |
| Melt Point(°C) | 132-134°C |
| 1. Gen-Qiang Chen, Yan-Fei Xia, Jin-Ming Yang, Zhi-Ping Che, Di Sun, Shen Li, Yue-E Tian, Sheng-Ming Liu, Jia Jiang, Xiao-Min Lin. (2020) Controlled synthesis of N, N-dimethylarylsulfonamide derivatives as nematicidal agents. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, [PMID:31773971] [10.1080/10286020.2019.1694513] |
| 2. Zhang Chunhua, Wu Huiqin, Huang Xiaolan, Zhu Zhixin, Luo Huitai, Huang Fang, Lin Xiaoshan. (2012) Simultaneous Determination of Toxic Alkaloids in Blood and Urine by HPLC–ESI–MS/MS. CHROMATOGRAPHIA, 75 (9): (499-511). [PMID:] [10.1007/s10337-012-2216-6] |
| 3. Lin-Song Teng, Zhen-Dong Ying, Xiao-Han Sun, Hao-Cheng Hou, Shi-Dong Qiu, Peng Liu, Ke-Jing Li, Lei Zhang, Xie-Huang Sheng. (2025) Formoterol, a clinically approved drug, inhibits ferroptosis by suppressing lipid peroxidation and attenuates APAP-induced acute liver injury. CHEMICO-BIOLOGICAL INTERACTIONS, [PMID:40914538] [10.1016/j.cbi.2025.111724] |
| 4. Huiyu He, Rui Wang, Rongbin Nie, Nan Dong. (2025) An environmentally friendly cucurbit[7]uril-mediated magnetic-assisted matrix solid-phase dispersion extraction combined with HPLC-MS/MS for multiple analysis of pharmaceuticals and personal care products in aquatic organisms. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2025.115146] |
