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Dual specificity mitogen-activated protein kinase kinase 4 (MAP2K4)

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  1. Genistein - analytical standard，≥98%, used for , CAS No. 446-72-0, by Aladdin Scientific
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    Genistein, Activator of CFTR;Agonist of Estrogen receptor-β;Agonist of Estrogen-related receptor-α;Agonist of Estrogen-related receptor-β;Agonist of Estrogen-related receptor-γ;Agonist of TAS2R14;Agonist of TAS2R39;Activator of TRPC5
    CAS: 446-72-0 EC Number: 207-174-9 Formula: C15H10O5 Molecular Weight: 270.24
    Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: G106672
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    IUPAC Name
    5,7-dihydroxy-3-(4-hydroxyphenyl)chromen-4-one
    SMILES
    C1=CC(=CC=C1C2=COC3=CC(=CC(=C3C2=O)O)O)O
    InChIKey
    TZBJGXHYKVUXJN-UHFFFAOYSA-N
    InChI
    1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,16-18H
    Synonyms
    cid_5280961 | GTPL2826 | BRN 0263823 | DH2M523P0H | MolMap_000022 | GENISTEIN (USP-RS) | Differenol A | GENISTEIN [MI...
  2. SL-327, Inhibitor of mitogen-activated protein kinase kinase 2
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    SL-327, Inhibitor of mitogen-activated protein kinase kinase 2
    CAS: 305350-87-2 EC Number: 878-717-0 PubChem CID: 9549284 Formula: C16H12F3N3S Molecular Weight: 335.35
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98% mixture of isomers
    In Stock Item #: S125929
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    Technical Identifiers
    IUPAC Name
    (Z)-3-amino-3-(4-aminophenyl)sulfanyl-2-[2-(trifluoromethyl)phenyl]prop-2-enenitrile
    SMILES
    C1=CC=C(C(=C1)C(=C(N)SC2=CC=C(C=C2)N)C#N)C(F)(F)F
    InChIKey
    JLOXTZFYJNCPIS-FYWRMAATSA-N
    InChI
    1S/C16H12F3N3S/c17-16(18,19)14-4-2-1-3-12(14)13(9-20)15(22)23-11-7-5-10(21)6-8-11/h1-8H,21-22H2/b15-13+
    Synonyms
    CCG-206867 | STL555675 | Benzeneacetonitrile, alpha-[amino[(4-aminophenyl)thio]methylene]-2-(trifluoromethyl)- | HY-1...
  3. MLN2480, RAF serine/threonine protein kinase inhibitor
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    MLN2480, RAF serine/threonine protein kinase inhibitor
    CAS: 1096708-71-2 Formula: C17H12Cl2F3N7O2S Molecular Weight: 506.29
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: M275976
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    Technical Identifiers
    IUPAC Name
    2-[(1R)-1-[(6-amino-5-chloropyrimidine-4-carbonyl)amino]ethyl]-N-[5-chloro-4-(trifluoromethyl)pyridin-2-yl]-1,3-thiazole-5-carboxamide
    SMILES
    CC(C1=NC=C(S1)C(=O)NC2=NC=C(C(=C2)C(F)(F)F)Cl)NC(=O)C3=C(C(=NC=N3)N)Cl
    InChIKey
    VWMJHAFYPMOMGF-ZCFIWIBFSA-N
    InChI
    1S/C17H12Cl2F3N7O2S/c1-6(28-15(31)12-11(19)13(23)27-5-26-12)16-25-4-9(32-16)14(30)29-10-2-7(17(20,21)22)8(18)3-24-10/h2-6H,1H3,(H,28,31)(H2,23,26,27)(show more
    Synonyms
    17-Ethinyl-3,17-oestradiol | 6-AMINO-5-CHLORO-N-[(1R)-1-(5-{[5-CHLORO-4-(TRIFLUOROMETHYL)PYRIDIN-2-YL]CARBAMOYL}-1,3-...
  4. Genistein
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    Genistein
    CAS: 446-72-0 EC Number: 207-174-9 Formula: C15H10O5 Molecular Weight: 270.24
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    In Stock Item #: G106673
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    5,7-dihydroxy-3-(4-hydroxyphenyl)chromen-4-one
    SMILES
    C1=CC(=CC=C1C2=COC3=CC(=CC(=C3C2=O)O)O)O
    InChIKey
    TZBJGXHYKVUXJN-UHFFFAOYSA-N
    InChI
    1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,16-18H
    Synonyms
    cid_5280961 | GTPL2826 | BRN 0263823 | DH2M523P0H | MolMap_000022 | GENISTEIN (USP-RS) | Differenol A | GENISTEIN [MI...
  6. MLN2480, RAF serine/threonine protein kinase inhibitor
    Wish List Compare
    MLN2480, RAF serine/threonine protein kinase inhibitor
    CAS: 1096708-71-2 Formula: C17H12Cl2F3N7O2S Molecular Weight: 506.29
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: M420574
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    2-[(1R)-1-[(6-amino-5-chloropyrimidine-4-carbonyl)amino]ethyl]-N-[5-chloro-4-(trifluoromethyl)pyridin-2-yl]-1,3-thiazole-5-carboxamide
    SMILES
    CC(C1=NC=C(S1)C(=O)NC2=NC=C(C(=C2)C(F)(F)F)Cl)NC(=O)C3=C(C(=NC=N3)N)Cl
    InChIKey
    VWMJHAFYPMOMGF-ZCFIWIBFSA-N
    InChI
    1S/C17H12Cl2F3N7O2S/c1-6(28-15(31)12-11(19)13(23)27-5-26-12)16-25-4-9(32-16)14(30)29-10-2-7(17(20,21)22)8(18)3-24-10/h2-6H,1H3,(H,28,31)(H2,23,26,27)(show more
    Synonyms
    17-Ethinyl-3,17-oestradiol | 6-AMINO-5-CHLORO-N-[(1R)-1-(5-{[5-CHLORO-4-(TRIFLUOROMETHYL)PYRIDIN-2-YL]CARBAMOYL}-1,3-...
  7. SL-327, Inhibitor of mitogen-activated protein kinase kinase 2
    Wish List Compare
    SL-327, Inhibitor of mitogen-activated protein kinase kinase 2
    CAS: 305350-87-2 EC Number: 878-717-0 PubChem CID: 9549284 Formula: C16H12F3N3S Molecular Weight: 335.35
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: S423164
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    (Z)-3-amino-3-(4-aminophenyl)sulfanyl-2-[2-(trifluoromethyl)phenyl]prop-2-enenitrile
    SMILES
    C1=CC=C(C(=C1)C(=C(N)SC2=CC=C(C=C2)N)C#N)C(F)(F)F
    InChIKey
    JLOXTZFYJNCPIS-FYWRMAATSA-N
    InChI
    1S/C16H12F3N3S/c17-16(18,19)14-4-2-1-3-12(14)13(9-20)15(22)23-11-7-5-10(21)6-8-11/h1-8H,21-22H2/b15-13+
    Synonyms
    CCG-206867 | STL555675 | Benzeneacetonitrile, alpha-[amino[(4-aminophenyl)thio]methylene]-2-(trifluoromethyl)- | HY-1...
  8. no_selection
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    2-[[1-cyclopentyl-5-[1-(oxetan-3-yl)piperidin-4-yl]pyrazol-3-yl]amino]pyridine-4-carbonitrile, Inhibitor of mitogen-activated protein kinase 10;Inhibitor of mitogen-activated protein kinase 8;Inhibitor of mitogen-activated protein kinase kinase 4;Inhibitor of mitogen-activated protein kinase kinase 7;Inhibitor of mitogen-activated protein kinase ki
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: C608666
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    2-[[1-cyclopentyl-5-[1-(oxetan-3-yl)piperidin-4-yl]pyrazol-3-yl]amino]pyridine-4-carbonitrile
    SMILES
    N#Cc1ccnc(c1)Nc1cc(n(n1)C1CCCC1)C1CCN(CC1)C1COC1
    InChIKey
    GMTAOJMPNXLKJI-UHFFFAOYSA-N
    InChI
    1S/C22H28N6O/c23-13-16-5-8-24-21(11-16)25-22-12-20(28(26-22)18-3-1-2-4-18)17-6-9-27(10-7-17)19-14-29-15-19/h5,8,11-12,17-19H,1-4,6-7,9-10,14-15H2,(H,2show more
    Synonyms
    compound 11
  9. no_selection
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    darizmetinib, Inhibitor of mitogen-activated protein kinase kinase 4
    CAS: 2369583-33-3 PubChem CID: 139369660 Formula: C21H17F2N5O3S Molecular Weight: 457.45
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: D609742
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    Technical Identifiers
    IUPAC Name
    N-[2,6-difluoro-3-(5-pyridin-4-yl-2H-pyrazolo[3,4-b]pyridine-3-carbonyl)phenyl]propane-1-sulfonamide
    SMILES
    CCCS(=O)(=O)Nc1c(ccc(c1F)C(=O)c1c2cc(cnc2n[nH]1)c1ccncc1)F
    InChIKey
    WBNMARNYIFMNEP-UHFFFAOYSA-N
    InChI
    1S/C21H17F2N5O3S/c1-2-9-32(30,31)28-19-16(22)4-3-14(17(19)23)20(29)18-15-10-13(11-25-21(15)27-26-18)12-5-7-24-8-6-12/h3-8,10-11,28H,2,9H2,1H3,(H,25,26show more
    Synonyms
    HY-152860 | 1-Propanesulfonamide, N-[2,6-difluoro-3-[[5-(4-pyridinyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]carbonyl]phenyl]...
  10. Darizmetinib
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    Darizmetinib
    CAS: 2369583-33-3 PubChem CID: 139369660 Formula: C21H17F2N5O3S Molecular Weight: 457.45
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    Out of Stock Item #: D1497869
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    Technical Identifiers
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