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Vascular endothelial growth factor receptor 3 (FLT4)

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  1. SAR131675
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    SAR131675
    CAS: 1433953-83-3 PubChem CID: 71295845 Formula: C18H22N4O4 Molecular Weight: 358.39
    ≥98%
    In Stock Item #: S126571
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    IUPAC Name
    2-amino-1-ethyl-7-[(3R)-3-hydroxy-4-methoxy-3-methylbut-1-ynyl]-N-methyl-4-oxo-1,8-naphthyridine-3-carboxamide
    SMILES
    CCN1C(=C(C(=O)C2=C1N=C(C=C2)C#CC(C)(COC)O)C(=O)NC)N
    InChIKey
    PFMPOBVAYMTUOX-GOSISDBHSA-N
    InChI
    1S/C18H22N4O4/c1-5-22-15(19)13(17(24)20-3)14(23)12-7-6-11(21-16(12)22)8-9-18(2,25)10-26-4/h6-7,25H,5,10,19H2,1-4H3,(H,20,24)/t18-/m1/s1
    Synonyms
    (R)-2-amino-1-ethyl-7-(3-hydroxy-4-methoxy-3-methylbut-1-ynyl)-N-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxa...
  2. OSI-906 (Linsitinib), Inhibitor of Insulin-like growth factor I receptor;Inhibitor of Insulin receptor;Inhibitor of Insulin receptor-related receptor
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    OSI-906 (Linsitinib), Inhibitor of Insulin-like growth factor I receptor;Inhibitor of Insulin receptor;Inhibitor of Insulin receptor-related receptor
    CAS: 867160-71-2 Formula: C26H23N5O Molecular Weight: 421.51
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    In Stock Item #: L126224
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    IUPAC Name
    3-[8-amino-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutan-1-ol
    SMILES
    CC1(CC(C1)C2=NC(=C3N2C=CN=C3N)C4=CC5=C(C=C4)C=CC(=N5)C6=CC=CC=C6)O
    InChIKey
    PKCDDUHJAFVJJB-UHFFFAOYSA-N
    InChI
    1S/C26H23N5O/c1-26(32)14-19(15-26)25-30-22(23-24(27)28-11-12-31(23)25)18-8-7-17-9-10-20(29-21(17)13-18)16-5-3-2-4-6-16/h2-13,19,32H,14-15H2,1H3,(H2,27show more
    Synonyms
    Linsitinib (USAN/INN) | Cis-3-(8-Amino-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl)-1-methylcyclobutan-1-ol |...
  3. SNS-314 Mesylate
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    SNS-314 Mesylate
    CAS: 1146618-41-8 PubChem CID: 24995523 Formula: C18H15ClN6OS2.CH4O3S Molecular Weight: 527.04
    ≥98%
    In Stock Item #: S128045
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    IUPAC Name
    1-(3-chlorophenyl)-3-[5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-1,3-thiazol-2-yl]urea;methanesulfonic acid
    SMILES
    CS(=O)(=O)O.C1=CC(=CC(=C1)Cl)NC(=O)NC2=NC=C(S2)CCNC3=NC=NC4=C3SC=C4
    InChIKey
    FYCODPVDEFFWSR-UHFFFAOYSA-N
    InChI
    1S/C18H15ClN6OS2.CH4O3S/c19-11-2-1-3-12(8-11)24-17(26)25-18-21-9-13(28-18)4-6-20-16-15-14(5-7-27-15)22-10-23-16;1-5(2,3)4/h1-3,5,7-10H,4,6H2,(H,20,22,show more
    Synonyms
    BCP24792 | HMS3654A12 | MLS006011040 | SCHEMBL17257952 | N-(3-Chlorophenyl)-N'-[5-[2-(thieno[3,2-d]pyrimidin-4-ylamin...
  4. Vandetanib, Epidermal growth factor receptor inhibitor
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    Vandetanib, Epidermal growth factor receptor inhibitor
    CAS: 443913-73-3 EC Number: 669-841-4 PubChem CID: 3081361 Formula: C22H24BrFN4O2 Molecular Weight: 475.36
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    In Stock Item #: V125180
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    IUPAC Name
    N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine
    SMILES
    CN1CCC(CC1)COC2=C(C=C3C(=C2)N=CN=C3NC4=C(C=C(C=C4)Br)F)OC
    InChIKey
    UHTHHESEBZOYNR-UHFFFAOYSA-N
    InChI
    1S/C22H24BrFN4O2/c1-28-7-5-14(6-8-28)12-30-21-11-19-16(10-20(21)29-2)22(26-13-25-19)27-18-4-3-15(23)9-17(18)24/h3-4,9-11,13-14H,5-8,12H2,1-2H3,(H,25,2show more
    Synonyms
    ZD6474 | N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-[(1-methyl-4-piperidinyl)methoxy]-4-quinazolinamine | N-(4-Bromo-2-fl...
  5. Vatalanib succinate
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    Vatalanib succinate
    CAS: 212142-18-2 EC Number: 658-085-0 PubChem CID: 151193 Formula: C20H15ClN4•C4H6O4 Molecular Weight: 464.90
    ≥99%(HPLC)
    In Stock Item #: V286725
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    IUPAC Name
    butanedioic acid;N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine
    SMILES
    C1=CC=C2C(=C1)C(=NN=C2NC3=CC=C(C=C3)Cl)CC4=CC=NC=C4.C(CC(=O)O)C(=O)O
    InChIKey
    LLDWLPRYLVPDTG-UHFFFAOYSA-N
    InChI
    1S/C20H15ClN4.C4H6O4/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14;5-3(6)1-2-4(7)8/h1-12H,13H2,(H,23,25);1-2H2,(H,5,6show more
    Synonyms
    1-(4-chloroanilino)-4-(4-pyridylmethyl)phthalazine succinate | PTK 787/ZK 222584 | 1-Phthalazinamine, N-(4-chlorophen...
  6. Lenvatinib (E7080), Inhibitor of fms related receptor tyrosine kinase 4;Inhibitor of kinase insert domain receptor
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    Lenvatinib (E7080), Inhibitor of fms related receptor tyrosine kinase 4;Inhibitor of kinase insert domain receptor
    CAS: 417716-92-8 EC Number: 970-217-1 Formula: C21H19ClN4O4 Molecular Weight: 426.85
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    In Stock Item #: L125518
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    IUPAC Name
    4-[3-chloro-4-(cyclopropylcarbamoylamino)phenoxy]-7-methoxyquinoline-6-carboxamide
    SMILES
    COC1=CC2=NC=CC(=C2C=C1C(=O)N)OC3=CC(=C(C=C3)NC(=O)NC4CC4)Cl
    InChIKey
    WOSKHXYHFSIKNG-UHFFFAOYSA-N
    InChI
    1S/C21H19ClN4O4/c1-29-19-10-17-13(9-14(19)20(23)27)18(6-7-24-17)30-12-4-5-16(15(22)8-12)26-21(28)25-11-2-3-11/h4-11H,2-3H2,1H3,(H2,23,27)(H2,25,26,28)
    Synonyms
    LENVATINIB [MI] | UNII-EE083865G2 | AS-16203 | LEV | NSC800781 | NSC-800781 | DB09078 | AKOS021983298 | LENVATINIB [I...
  7. Fruquintinib, Vascular endothelial growth factor receptor inhibitor
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    Fruquintinib, Vascular endothelial growth factor receptor inhibitor
    CAS: 1194506-26-7 EC Number: 962-485-3 Formula: C21H19N3O5 Molecular Weight: 393.39
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: F302543
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    IUPAC Name
    6-(6,7-dimethoxyquinazolin-4-yl)oxy-N,2-dimethyl-1-benzofuran-3-carboxamide
    SMILES
    CC1=C(C2=C(O1)C=C(C=C2)OC3=NC=NC4=CC(=C(C=C43)OC)OC)C(=O)NC
    InChIKey
    BALLNEJQLSTPIO-UHFFFAOYSA-N
    InChI
    1S/C21H19N3O5/c1-11-19(20(25)22-2)13-6-5-12(7-16(13)28-11)29-21-14-8-17(26-3)18(27-4)9-15(14)23-10-24-21/h5-10H,1-4H3,(H,22,25)
    Synonyms
    6-((6,7-dimethoxyquinazolin-4-yl)oxy)-N,2-dimethylbenzofuran-3-carboxamide | NSC801000 | NSC-801000 | C71641 | WHO 10...
  8. AAL 993
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    AAL 993
    CAS: 269390-77-4 Formula: C20H16N3OF3 Molecular Weight: 371.4
    ≥98%
    In Stock Item #: A275890
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    IUPAC Name
    2-(pyridin-4-ylmethylamino)-N-[3-(trifluoromethyl)phenyl]benzamide
    SMILES
    C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NCC3=CC=NC=C3
    InChIKey
    BLAFVGLBBOPRLP-UHFFFAOYSA-N
    InChI
    1S/C20H16F3N3O/c21-20(22,23)15-4-3-5-16(12-15)26-19(27)17-6-1-2-7-18(17)25-13-14-8-10-24-11-9-14/h1-12,25H,13H2,(H,26,27)
    Synonyms
    2-[(4-Pyridinylmethyl)amino]-N-[3-(trifluoromethyl)phenyl]benzamide
  9. Telatinib, Vascular endothelial growth factor receptor 3 inhibitor
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    Telatinib, Vascular endothelial growth factor receptor 3 inhibitor
    CAS: 332012-40-5 PubChem CID: 9808844 Formula: C20H16ClN5O3 Molecular Weight: 409.83
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: T129747
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    IUPAC Name
    4-[[4-(4-chloroanilino)furo[2,3-d]pyridazin-7-yl]oxymethyl]-N-methylpyridine-2-carboxamide
    SMILES
    CNC(=O)C1=NC=CC(=C1)COC2=NN=C(C3=C2OC=C3)NC4=CC=C(C=C4)Cl
    InChIKey
    QFCXANHHBCGMAS-UHFFFAOYSA-N
    InChI
    1S/C20H16ClN5O3/c1-22-19(27)16-10-12(6-8-23-16)11-29-20-17-15(7-9-28-17)18(25-26-20)24-14-4-2-13(21)3-5-14/h2-10H,11H2,1H3,(H,22,27)(H,24,25)
    Synonyms
    2-Pyridinecarboxamide, 4-(((4-((4-chlorophenyl)amino)furo(2,3-d)pyridazin-7-yl)oxy)methyl)-N-methyl- | 4-({[4-(4-Chlo...
  10. Sulfatinib, Vascular endothelial growth factor receptor inhibitor
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    Sulfatinib, Vascular endothelial growth factor receptor inhibitor
    CAS: 1308672-74-3 Formula: C24H28N6O3S Molecular Weight: 480.58
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: N190510
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    IUPAC Name
    N-[2-(dimethylamino)ethyl]-1-[3-[[4-[(2-methyl-1H-indol-5-yl)oxy]pyrimidin-2-yl]amino]phenyl]methanesulfonamide
    SMILES
    CC1=CC2=C(N1)C=CC(=C2)OC3=NC(=NC=C3)NC4=CC=CC(=C4)CS(=O)(=O)NCCN(C)C
    InChIKey
    TTZSNFLLYPYKIL-UHFFFAOYSA-N
    InChI
    1S/C24H28N6O3S/c1-17-13-19-15-21(7-8-22(19)27-17)33-23-9-10-25-24(29-23)28-20-6-4-5-18(14-20)16-34(31,32)26-11-12-30(2)3/h4-10,13-15,26-27H,11-12,16H2show more
    Synonyms
    D71057 | Surufatinib [INN] | HY-12297 | C.I. 16255 | AS-74954 | B2K5L1L8S9 | GTPL9769 | Benzenemethanesulfonamide, N-...
  11. E-3810, Fibroblast growth factor receptor 2 inhibitor
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    E-3810, Fibroblast growth factor receptor 2 inhibitor
    CAS: 1058137-23-7 Formula: C26H25N3O4 Molecular Weight: 443.49
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: E127640
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    IUPAC Name
    6-[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]oxy-N-methylnaphthalene-1-carboxamide
    SMILES
    CNC(=O)C1=CC=CC2=C1C=CC(=C2)OC3=C4C=C(C(=CC4=NC=C3)OCC5(CC5)N)OC
    InChIKey
    CUDVHEFYRIWYQD-UHFFFAOYSA-N
    InChI
    1S/C26H25N3O4/c1-28-25(30)19-5-3-4-16-12-17(6-7-18(16)19)33-22-8-11-29-21-14-24(23(31-2)13-20(21)22)32-15-26(27)9-10-26/h3-8,11-14H,9-10,15,27H2,1-2H3show more
    Synonyms
    1,13-dimethyl-10-(3-methyl-2-butenyl)-(1R,9R,13R)-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol(Pentazocine) ...
  12. Axitinib, Vascular endothelial growth factor receptor inhibitor
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    Axitinib, Vascular endothelial growth factor receptor inhibitor
    CAS: 319460-85-0 EC Number: 638-771-6 Formula: C22H18N4OS Molecular Weight: 386.47
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    In Stock Item #: A129732
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    IUPAC Name
    N-methyl-2-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfanyl]benzamide
    SMILES
    CNC(=O)C1=CC=CC=C1SC2=CC3=C(C=C2)C(=NN3)C=CC4=CC=CC=N4
    InChIKey
    RITAVMQDGBJQJZ-FMIVXFBMSA-N
    InChI
    1S/C22H18N4OS/c1-23-22(27)18-7-2-3-8-21(18)28-16-10-11-17-19(25-26-20(17)14-16)12-9-15-6-4-5-13-24-15/h2-14H,1H3,(H,23,27)(H,25,26)/b12-9+
    Synonyms
    AG13736 | AG-13736 | Benzamide, N-methyl-2-((3-((1E)-2-(2-pyridinyl)ethenyl)-1H-indazo)-6-yl)thio)- | NCGC00241108-04...
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