GRADE & PURITYBioReagent?BioReagent grade — tested suitable for life-science and molecular-biology use. Use for cell culture, assays, and biochemical work needing biological compatibility.
BioReagent BioReagent for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
🌡
Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
📋
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
📚
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
Malate Dehydrogenase (EC 1.1.1.37) is widely distributed in animals, plants, microorganisms, and cultured cells. In mitochondria, MDH functions as a key enzyme in the tricarboxylic acid (TCA) cycle, catalyzing the conversion of malate to oxaloacetate. Conversely, in the cytosol, MDH catalyzes the formation of malate from oxaloacetate. As oxaloacetate serves as a crucial intermediate connecting multiple important metabolic pathways, MDH plays a significant role in various cellular physiological processes, including mitochondrial energy metabolism, the malate-aspartate shuttle system, reactive oxygen species metabolism, and disease resistance. Based on coenzyme specificity, MDH is classified into NAD-dependent MDH (NAD-MDH) and NADP-dependent MDH (NADP-MDH). Bacteria typically contain only NAD-MDH, while in eukaryotic cells, NAD-MDH is distributed in both the cytoplasm and mitochondria.
Assay Principle: NAD-MDH catalyzes the reduction of oxaloacetate to malate using NADH, resulting in a decrease in absorbance at 340 nm.
Storage and Shipping
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at -20℃ for 6 months.
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
We use cookies to ensure the website functions properly and, where permitted, to improve your experience. You can manage your preferences at any time in Settings. Learn more in our Cookie Policy.
Shall we send you a message when we have discounts available?
Remind me later
Thank you! Please check your email inbox to confirm.
Products are supplied to verified businesses, institutions, and qualified professionals for research and development use only. Not for use in humans, animals, diagnosis, or therapy.
