10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 8 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Information
Noradrenaline bitartrate monohydrate (Levophed) is a direct alpha-adrenergic receptors stimulator.
In vitro
Noradrenaline modulates the gain of evoked activity, especially in sensory areas. Noradrenaline promotes long-term synaptic plasticity, in addition to these data emphasizing its short-term influence. Noradrenaline would signal ‘gross changes in the environment that produce sensory information strongly violating top-down expectations’ and would, through an enhancement of ‘bottom-up’ information processing at the expense of irrelevant ‘top-down’ expectations, favor behavioral adjustment. Noradrenaline modulates drive and energy and exerts a fine regulation of specific processes including learning, memory, sleep, arousal and adaptation. Noradrenaline system is intimately involved in a range of psychological processes which, when disrupted, lead to the expression of classifiable psychiatric disorders. Noradrenaline appears to be involved in a range of psychological processes, including arousal (vigilance), cognition, learning and sleep regulation, and also in regulating response to stressors which might initiate or exacerbate depressive symptomatology. Noradrenaline deficiency in this pathway may reduce concentration, affect working memory and cause psychomotor retardation, resulting in apathy and depression,while an increase in noradrenaline in this pathway is predicted to alleviate poor concentration, apathy and depression. Noradrenaline effects are complex and depending on experimental conditions (ponto-medullary and medullary preparations) and species (rats or mice), exogenous Noradrenaline mainly facilitates or mainly inhibits the neonatal RRG, with a mixture of α1 facilitatory and α2 inhibitory effects.
In vivo
Cell Data
cell lines：
Concentrations：
Incubation Time：
Powder Purity:≥99%
| Isomeric SMILES | C1=CC(=C(C=C1[C@H](CN)O)O)O.[C@@H]([C@H](C(=O)O)O)(C(=O)O)O.O |
|---|---|
| WGK Germany | 3 |
| RTECS | DN6750000 |
| Alternate CAS | 51-40-1 |
| Molecular Weight | 337.28 |
| Beilstein | 4078502 |
| Reaxy-Rn | 24708504 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=24708504&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
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| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 I2206005 | Certificate of Analysis | May 19, 2026 | N408442 |
| Solubility | Solubility (25°C) In vitro DMSO: 34 mg/mL (201.68 mM); Ethanol: 34 mg/mL (201.68 mM); Water: Insoluble; |
|---|---|
| Specific Rotation[α] | -10.0 to -12.0 deg(C=5, H2O) |
| Melt Point(°C) | 129 °C |
| 1. Yong Liu, Mingzhu Yang, Juanjuan Li, Wei Zhang, Xingyu Jiang. (2019) Plasma Treatment Conversion of Phenolic Compounds into Fluorescent Organic Nanoparticles for Cell Imaging. ANALYTICAL CHEMISTRY, [PMID:31006238] [10.1021/acs.analchem.9b00837] |
| 2. Xia Zhou, Miao Qin, Jun Zhu, Cong Wang, Guang Zhu, Hongyan Wang, Liangbao Yang. (2018) Rapid and sensitive surface-enhanced resonance Raman spectroscopy detection for norepinephrine in biofluids. JOURNAL OF RAMAN SPECTROSCOPY, 50 (3): (314-321). [PMID:] [10.1002/jrs.5519] |
| 3. Xiaomin Cao, Miao Qin, Pan Li, Binbin Zhou, Xianghu Tang, Meihong Ge, Liangbao Yang, Jinhuai Liu. (2018) Probing catecholamine neurotransmitters based on iron-coordination surface-enhanced resonance Raman spectroscopy label. SENSORS AND ACTUATORS B-CHEMICAL, [PMID:] [10.1016/j.snb.2018.04.117] |
| 4. Haiying Shen, Lianhua Dong, Yunhua Gao, Xia Wang, Xinhua Dai. (2023) Integrated Microwell Array-Based Microfluidic Chip with a Hand-Held Smartphone-Controlled Device for Nucleic Acid Detection. ANALYTICAL CHEMISTRY, [PMID:37787984] [10.1021/acs.analchem.3c03525] |
| 5. Yingying Lei, Khaista Rahman, Xiaojian Cao, Bing Yang, Wei Zhou, Aikebaier Reheman, Luxia Cai, Yifan Wang, Rohit Tyagi, Zhe Wang, Xi Chen, Gang Cao. (2023) Epinephrine Stimulates Mycobacterium tuberculosis Growth and Biofilm Formation. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24 (24): (17370). [PMID:38139199] [10.3390/ijms242417370] |
| 6. Haiying Shen, Feng Qu, Yong Xia, Xingyu Jiang. (2018) Straightforward and Ultrastable Surface Modification of Microfluidic Chips with Norepinephrine Bitartrate Improves Performance in Immunoassays. ANALYTICAL CHEMISTRY, [PMID:29478312] [10.1021/acs.analchem.7b05186] |
| 7. Shanying Han, Tianyu Du, Hui Jiang, Xuemei Wang. (2016) Synergistic effect of pyrroloquinoline quinone and graphene nano-interface for facile fabrication of sensitive NADH biosensor. BIOSENSORS & BIOELECTRONICS, [PMID:27156055] [10.1016/j.bios.2016.04.092] |
| 8. Meizhu Wu, Yuting Zhou, Zhi Guo, Dawei Lian, Hong Chen, Renfeng Li, Jing Lin, Farman Ali, Aling Shen, Jun Peng. (2025) Isoliensinine promotes vasorelaxation and inhibits constriction by regulating the calcium channel in hypertension: In vitro and in vivo approaches. EUROPEAN JOURNAL OF PHARMACOLOGY, [PMID:40414594] [10.1016/j.ejphar.2025.177765] |
