Periodic acid - ≥99% , CAS No.10450-60-9

CAS: 10450-60-9 Cat. No.: P104608 Molecular Weight: 227.94 EC Number: 233-937-0

GRADE & PURITY ≥99%

Synonyms

ortho periodicacid | pentahydroxy-l5-iodane oxide | UNII-AK1D44L87G | Periodic acid, ACS | BB 0256569 | Periodic(VII) acid | pentahydroxy(oxo)-lambda7-iodane | Periodic acid (H5IO6) | Pentahydroxy-lambda5-iodane oxide

Storage

Protected from light,Room temperature,Desiccated,Cool

Shipped In

FedEx DG Service

Overview

can be used in the following reactions:      
Oxidation of alcohols to ketones and aldehydes.
Oxidation hydroxylamine derivatives.    
Oxidation of arenes to quinones.
It can also be used:     
As a stoichiometric oxidant with chromium (IV) acetate for the oxidation of tertiary C−H bonds to tertiary alcohols.     
In combination with chromium oxide to oxidize primary alcohols to carboxylic acids; alkylbenzenes to benzoic acids; and cyclic benzyl ethers to the corresponding lactones.      
In the selective oxidation of sulfides to sulfoxides using FeCl3 as a catalyst.

Specifications

Synonyms

ortho periodicacid | pentahydroxy-l5-iodane oxide | UNII-AK1D44L87G | Periodic acid, ACS | BB 0256569 | Periodic(VII) acid | pentahydroxy(oxo)-lambda7-iodane | Periodic acid (H5IO6) | Pentahydroxy-lambda5-iodane oxide

Specifications & Purity

≥99%

Storage

Protected from light, Room temperature, Desiccated, Cool

Shipped In

FedEx DG Service

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥99%

Names and Identifiers

• Canonical Smiles: OI(=O)(O)(O)(O)O
• IUPAC Name: pentahydroxy(oxo)-λ7-iodane
• InChIKey: TWLXDPFBEPBAQB-UHFFFAOYSA-N
• INCHI: 1S/H5IO6/c2-1(3,4,5,6)7/h(H5,2,3,4,5,6,7)
• Isomeric SMILES: OI(=O)(O)(O)(O)O
• WGK Germany: 3
• UN Number: 3085
• Packing Group: II
• Molecular Weight: 227.94

Taxonomic Classification

Taxonomy Tree

• Kingdom Inorganic compounds
  • Superclass Homogeneous non-metal compounds
    • Class Halogen organides
      • Subclass Halogen oxides

• Kingdom: Inorganic compounds
• Superclass: Homogeneous non-metal compounds
• Class: Halogen organides
• Subclass: Halogen oxides
• Intermediate Tree Nodes: Not available
• Direct Parent: Halogen oxides
• Alternative Parents: Inorganic oxides
• Molecular Framework: Not available
• Substituents: Halogen oxide - Inorganic oxide
• Description: This compound belongs to the class of inorganic compounds known as halogen oxides. These are inorganic compounds containing an oxygen atom of an oxidation state of -2, in which the heaviest atom bonded to the oxygen is a halogen.
• External Descriptors: iodine oxoacid

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Soluble in water and alcohols.
• Sensitivity: Hygroscopic,Light sensitive
• Melt Point(°C): 122°C
• Molecular Weight: 227.940 g/mol
• XLogP3: -2.100
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 0
• Exact Mass: 227.913 Da
• Monoisotopic Mass: 227.913 Da
• Topological Polar Surface Area: 118.000 Ų
• Heavy Atom Count: 7
• Formal Charge: 0
• Complexity: 122.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

1. Zhaoyi Lin, Weike Xie, Zhenhua Cui, Jiana Huang, Hao Cao, Yan Li.  (2023)  3D printed alginate/gelatin-based porous hydrogel scaffolds to improve diabetic wound healing.  GIANT,      [PMID:] [10.1016/j.giant.2023.100185]

2. Siqi Chen, Tingting Li, Donglian Deng, Xiaoyue Zhang, Yibing Ji, Ruijun Li.  (2021)  Gold nanoparticles in situ generated on carbon dots grafted paper: application in enantioselective fluorescence sensing of D-alanine.  NEW JOURNAL OF CHEMISTRY,  45  (43): (20419-20425).  [PMID:] [10.1039/D1NJ03733A]

3. Yuan-Bin Fang, Rui-Biao Fu, Hong-Xin Tang, Qi-Rui Shui, Zu-Ju Ma, Xin-Tao Wu.  (2021)  Titanium Iodates with a Second-Harmonic-Generation Response.  INORGANIC CHEMISTRY,      [PMID:33779158] [10.1021/acs.inorgchem.1c00158]

4. Qian-Ming Huang, Chun-Li Hu, Bing-Ping Yang, Ru-Ling Tang, Jin Chen, Zhi Fang, Bingxuan Li, Jiang-Gao Mao.  (2020)  Ba2[MoO3(OH)(IO3)2]IO3: A Promising SHG Material Featuring a Λ-Shaped Functional Motif Achieved by Universal Mono-Site Substitution.  CHEMISTRY OF MATERIALS,      [PMID:] [10.1021/acs.chemmater.0c02657]

5. Lu Dai, Xixi Wang, Zhiyang Bu, Bo-Geng Li, Suyun Jie.  (2018)  Facile access to carboxyl-terminated polybutadiene and polyethylene from cis-polybutadiene rubber.  JOURNAL OF APPLIED POLYMER SCIENCE,  136  (2): (46934).  [PMID:] [10.1002/app.46934]

6. Qinzhuo Zhou, Anqi Wang, Lu Dai, Suyun Jie, Bo-Geng Li.  (2016)  Cleavable polybutadiene rubber: A versatile precursor to hydroxyl-terminated or multi-hydroxyl polybutadiene and polyethylene.  POLYMER,      [PMID:] [10.1016/j.polymer.2016.11.033]

7. Chunye Liu, Xuejiao Zhang, Hui Jing, Yanqing Miao, Lingzhi Zhao, Yan Han, Cuixia Cui.  (2015)  Research on drug–receptor interactions and prediction of drug activity via oriented immobilized receptor capillary electrophoresis.  ELECTROPHORESIS,  36  (19): (2433-2441).  [PMID:26105113] [10.1002/elps.201400583]

8. Qinzhuo Zhou, Suyun Jie, Bo-Geng Li.  (2015)  Facile synthesis of novel HTPBs and EHTPBs with high cis-1,4 content and extremely low glass transition temperature.  POLYMER,      [PMID:] [10.1016/j.polymer.2015.04.078]

9. Qinzhuo Zhou, Suyun Jie, Bo-Geng Li.  (2014)  Preparation of Hydroxyl-Terminated Polybutadiene with High Cis-1,4 Content.  INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH,      [PMID:] [10.1021/ie503652g]

10. Boyu Yang, Chao Li, Yongshuo Ren, Weichen Wang, Xiangxiang Zhang, Xiaojun Han.  (2024)  Construction of the Glycolysis Metabolic Pathway Inside an Artificial Cell for the Synthesis of Amino Acid and Its Reversible Deformation.  Journal of the American Chemical Society,      [PMID:39042264] [10.1021/jacs.4c06227]

11. Liwen Zhang, Luyao Xi, Shuyu He, Huizi Wen, Shanyi Tan, Shaohua Chen.  (2024)  Riboflavin derivatives as a novel electron transfer mediator for enhancing Cr(VI) removal by Shewanella oneidensis MR-1.  INTERNATIONAL BIODETERIORATION & BIODEGRADATION,      [PMID:] [10.1016/j.ibiod.2024.105892]

12. Tingting Yan, Han Li, Dongyang Xi, Linan Liu, Dinghan Jin, Lei Sun.  (2025)  Synthesis and pressure-induced structural phase transition of energetic molecular perovskite DAI-1.  SOLID STATE SCIENCES,      [PMID:] [10.1016/j.solidstatesciences.2025.107864]

13. Tingting Hong, Yan Zheng, Wenwen Hu, Yibing Ji.  (2014)  Preparation and evaluation of bovine serum albumin immobilized chiral monolithic column for affinity capillary electrochromatography.  ANALYTICAL BIOCHEMISTRY,      [PMID:25062851] [10.1016/j.ab.2014.07.015]

14. Linhao Wang, Jia Wei, Jiangkai Huo, Wei Ji, Xiaohui Zhang, Yanan Li, Jiamei Li, Nan Cui, Wenhao Yan, Yuxin Zhao, Jun Li, Ju Wang.  (2025)  Harnessing Electronically Core-Shell CoFe Alloy-Carbon from Prussian Blue Analogues for Efficient Pollutant Abatement via Peracetic Acid Activation: Dual Reactive Species Generation and Synergistic Mechanisms.  APPLIED CATALYSIS B-ENVIRONMENTAL,      [PMID:] [10.1016/j.apcatb.2025.125284]

15. Chunye Liu, Xuejiao Zhang, Hui Jing, Jingshui Zhang, Yanqing Miao, Xifeng Zhai, Songyi Chen.  (2018)  Using open-tubular capillary electrochromatography with part-coating column for binding constants determination of β2-adrenergic receptor with seven drugs.  ELECTROPHORESIS,  40  (2): (289-295).  [PMID:30325031] [10.1002/elps.201800207]

16. Yusi Tian, Jiahui Shang, Wenyue Li, Chunxiang Jia, Zhiwei Gao, Liqiang Zhang, Yuwei Pan, Shang Gao.  (2025)  Boric acid modified zero-valent iron enhanced activation of periodate for sulfamethazine removal: Performance and mechanism.  Water Cycle,      [PMID:] [10.1016/j.watcyc.2025.12.002]

17. Minghua Nie, Meiqi Su, Yue Zhang, Yuyan Liu, Caixia Yan.  (2026)  Degradation of acetaminophen in fresh urine by periodate: Mechanisms, influencing factors and toxicity assessment.  Environmental Technology & Innovation,      [PMID:] [10.1016/j.eti.2026.104850]