Thionucleosides

Description:

Nucleoside analogues that contain a thiolane or a thietane that is 1,3-disubstituted with a hydroxyl group and pyrimidine or purine base, at the 1- and 3-position, respectively.

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  1. 4'-Thiouridine
    CAS: 6741-73-7 Formula: C9H12N2O5S Molecular Weight: 260.27
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    Out of Stock Item #: T1044181
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    Technical Identifiers
    IUPAC Name
    1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)thiolan-2-yl]pyrimidine-2,4-dione
    SMILES
    C1=CN(C(=O)NC1=O)C2C(C(C(S2)CO)O)O
    InChIKey
    MUSPKJVFRAYWAR-XVFCMESISA-N
    InChI
    1S/C9H12N2O5S/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1
    Synonyms
    1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrothiophen-2-yl)pyrimidine-2,4(1H,3H)-dione | 1-(4-thio-beta-...
  2. Cytidine, 4'-thio-
    CAS: 93080-09-2 Formula: C9H13N3O4S Molecular Weight: 259.279
    Out of Stock Item #: C1249062
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    IUPAC Name
    4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)thiolan-2-yl]pyrimidin-2-one
    SMILES
    C1=CN(C(=O)N=C1N)[C@H]2[C@@H]([C@@H]([C@H](S2)CO)O)O
    InChIKey
    GAKJJSAXUFZQTL-XVFCMESISA-N
    InChI
    1S/C9H13N3O4S/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6-,7-,8-/m1/s1
  3. Thiarabine
    CAS: 26599-17-7 PubChem CID: 168566 Formula: C9H13N3O4S Molecular Weight: 259.28
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: T646680
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    Technical Identifiers
    IUPAC Name
    4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)thiolan-2-yl]pyrimidin-2-one
    SMILES
    C1=CN(C(=O)N=C1N)C2C(C(C(S2)CO)O)O
    InChIKey
    GAKJJSAXUFZQTL-CCXZUQQUSA-N
    InChI
    1S/C9H13N3O4S/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6-,7+,8-/m1/s1
    Synonyms
    HY-16496 | UNII-YCO2764D5Z | THIARABINE [WHO-DD] | 4'-thio-beta-D-arabinofuranosylcytosine | YCO2764D5Z | 4-amino-1-(...
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