TMRE [Tetramethylrhodamine, ethyl ester, perchlorate] - for fluorescence analysis, ≥90%(HPCE) , CAS No.115532-52-0

CAS: 115532-52-0 Cat. No.: T131055 Molecular Weight: 514.955 EC Number: 635-011-5 PubChem CID: 2762682

GRADE & PURITY for Fluorescence analysis, ≥90%(HPCE)

Synonyms

CHEBI:78720 | Tetramethylrhodamine ethyl ester perchlorate, suitable for fluorescence, >=90% (HPCE) | Xanthylium, 3,6-bis(dimethylamino)-9-[2-(ethoxycarbonyl)phenyl]-, perchlorate (1:1) | AC-25823 | PD057626 | 3,6-Bis(dimethylamino)-9-(2-(ethoxycarbonyl)p

Storage

Store at 2-8°C,Protected from light,Argon charged

Shipped In

Wet ice

Overview

Tetramethylrhodamine ethyl ester perchlorate (TMRE), also known as TMRE perchlorate, is a potential mitochondrial dye. TMRE staining process is reversible, and it doesn’t affect cell proliferation and viability.
The sorted cells containing TMRE perchlorate don’t interfere with the subsequent functional assays and hence are a preferred choice for the enrichment of functionally active, unbiased cell populations.

Specifications

Synonyms

CHEBI:78720 | Tetramethylrhodamine ethyl ester perchlorate, suitable for fluorescence, >=90% (HPCE) | Xanthylium, 3, 6-bis(dimethylamino)-9-[2-(ethoxycarbonyl)phenyl]-, perchlorate (1:1) | AC-25823 | PD057626 | 3, 6-Bis(dimethylamino)-9-(2-(ethoxycarbonyl)p

Specifications & Purity

for fluorescence analysis, ≥90%(HPCE)

Storage

Store at 2-8°C, Protected from light, Argon charged

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

for Fluorescence analysis

Purity

≥90%(HPCE)

Names and Identifiers

• Canonical Smiles: CCOC(=O)C1=CC=CC=C1C2=C3C=CC(=[N+](C)C)C=C3OC4=C2C=CC(=C4)N(C)C.[O-]Cl(=O)(=O)=O
• IUPAC Name: [6-(dimethylamino)-9-(2-ethoxycarbonylphenyl)xanthen-3-ylidene]-dimethylazanium;perchlorate
• InChIKey: NBAOBNBFGNQAEJ-UHFFFAOYSA-M
• INCHI: 1S/C26H27N2O3.ClHO4/c1-6-30-26(29)20-10-8-7-9-19(20)25-21-13-11-17(27(2)3)15-23(21)31-24-16-18(28(4)5)12-14-22(24)25;2-1(3,4)5/h7-16H,6H2,1-5H3;(H,2,3,4,5)/q+1;/p-1
• Isomeric SMILES: CCOC(=O)C1=CC=CC=C1C2=C3C=CC(=[N+](C)C)C=C3OC4=C2C=CC(=C4)N(C)C.[O-]Cl(=O)(=O)=O
• WGK Germany: 3
• PubChem CID: 2762682
• Molecular Weight: 514.955

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Class Benzopyrans
      • Subclass 1-benzopyrans
        • Level5 Dibenzopyrans
          • Level6 Xanthenes

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Class: Benzopyrans
• Subclass: 1-benzopyrans
• Intermediate Tree Nodes: Dibenzopyrans
• Direct Parent: Xanthenes
• Alternative Parents: Benzoic acid esters Dialkylarylamines Benzoyl derivatives Organic perchlorates Organic perchlorate salts Secondary ketimines Heteroaromatic compounds Carboxylic acid esters Amino acids and derivatives Oxacyclic compounds Monocarboxylic acids and derivatives Organopnictogen compounds Organooxygen compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Xanthene - Benzoate ester - Benzoic acid or derivatives - Benzoyl - Tertiary aliphatic/aromatic amine - Dialkylarylamine - Monocyclic benzene moiety - Organic perchlorate - Organic perchlorate salt - Benzenoid - Secondary ketimine - Heteroaromatic compound - Tertiary amine - Amino acid or derivatives - Carboxylic acid ester - Organic chlorate - Oxacycle - Carboxylic acid derivative - Monocarboxylic acid or derivatives - Organic salt - Hydrocarbon derivative - Organonitrogen compound - Organooxygen compound - Organic oxide - Organopnictogen compound - Organic oxygen compound - Organic nitrogen compound - Amine - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as xanthenes. These are polycyclic aromatic compounds containing a xanthene moiety, which consists of two benzene rings joined to each other by a pyran ring.
• External Descriptors: xanthene dye - organic perchlorate salt

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Sensitivity: Air sensitive；Light sensitive
• Molecular Weight: 515.000 g/mol
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 5
• Exact Mass: 514.151 Da
• Monoisotopic Mass: 514.151 Da
• Topological Polar Surface Area: 116.000 Ų
• Heavy Atom Count: 36
• Formal Charge: 0
• Complexity: 884.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3