Product Name
Cetuximab (anti-EGFR) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to ERBB1/EGFR/HER1, >95%, Human IgG1, Antibody of epidermal growth factor receptor
Sinónimos
C225 | Recombinant Cetuximab Antibody | Cetuximab (anti-EGFR) | Cetuximab (C225) | Anti-ERBB1 / EGFR / HER1 Reference Antibody (cetuximab) | Avian erythroblastic leukemia viral (v erb b) oncogene homolog antibody | Cell growth inhibiting protein 40 antibo
Especificaciones y pureza
Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Mecanismos bioquímicos y fisiológicos
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin,
Especies hospedadoras
Human
Especificidad
ERBB1/EGFR/HER1
Aplicación
ELISA, Functional Assay, Flow cytometry, Kinetics (BLI), Kinetics (SPR)
Grado
Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Mecanismo de acción
Antibody of epidermal growth factor receptor
Tipo de anticuerpo
Primary antibody
Tipo de cadena ligera
kappa
SDS-PAGE
28.4 kDa (Light Chain) & 53.4 kDa (Heavy Chain), under reducing conditions; 184.2 kDa, under non-reducing conditions.
Método de purificación
Protein A purified