Product Name
Panitumumab (anti-EGFR) - Primary antibody, for Flow,ELISA,Functional Assay,Kinetics (BLI),Kinetics (SPR) various applications, specific to EGFR, >95%, Human IgG2SA, Antibody of epidermal growth factor receptor
Sinónimos
Panitumumab | ABX-EGF | Avian erythroblastic leukemia viral (v erb b) oncogene homolog antibody | Cell growth inhibiting protein 40 antibody | Cell proliferation inducing protein 61 antibody | EGF R antibody | EGFR antibody | EGFR_HUMAN antibody | Epiderm
Especificaciones y pureza
Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Mecanismos bioquímicos y fisiológicos
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin,
Especies hospedadoras
Human
Aplicación
Flow, ELISA, Functional Assay, Kinetics (BLI), Kinetics (SPR)
Grado
Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Mecanismo de acción
Antibody of epidermal growth factor receptor
Tipo de anticuerpo
Primary antibody
Tipo de cadena ligera
kappa
SDS-PAGE
26.8 kDa (Light Chain) & 52.0 kDa (Heavy Chain), under reducing conditions; 170.3 kDa, under non-reducing conditions.
Método de purificación
Protein A purified