Determine the necessary mass, volume, or concentration for preparing a solution.
Recombinant, EnzymoPure™, ≥5000 units/mg protein;from bovine pancreas Recombinant,EnzymoPure™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 43 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Bovine pancreatic deoxyribonuclease is an endonuclease which splits phosphodiester linkages, preferentially adjacent to a pyrimidine nucleotide yielding polynucleotides with free hydroxyl group at the 3' position and phosphate group at the 5' position. The average chain length of a limit digest is a tetranucleotide.
Bovine pancreatic deoxyribonuclease is an endonuclease which splits phosphodiester linkages, preferentially adjacent to a pyrimidine nucleotide yielding polynucleotides with free hydroxyl group at the 3' position and phosphate group at the 5' position. The average chain length of a limit digest is a tetranucleotide.
Used for the removal of DNA from protein samples. Deoxyribonuclease I from bovine pancreas has been used in a study to compare several procedures for reducing RNase contamination in preparations of DNase. Deoxyribonuclease I from bovine pancreas has also been used in a study to investigate the effect of the composition of sodium dodecyl sulfate preparations on the renaturation of enzymes after polyacrylamide gel electrophoresis.
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
| Certificate of Analysis | Jan 09, 2024 | D128586 |
| 1. Shaopeng Liu, Dan Peng, Shuohan He, Xuan Li, Yi Wu, Xin Liu, Yang Zhang, Peng Liu, Kaiyong Cai. (2023) Ternary low-temperature phototherapy nano-systems for the treatment of diabetic wounds. Journal of Materials Chemistry B, 12 (1): (264-274). [PMID:38088036] [10.1039/D3TB02224B] |
| 2. Chenfei Han, Yu Xiao, Zhenjiang Liu, Daolin Du, Ming Li. (2023) Cascade amplifying aptasensor for positively correlated detecting OTA: Based on DNase I-assisted cyclic enzyme digestion and AgNPs@gel-enhanced fluorescence. FOOD CONTROL, [PMID:] [10.1016/j.foodcont.2023.109970] |
| 3. Ningning Lei, Xu Peng, Mengyue Hu, Chang Wan, Xixun Yu. (2023) Research on essential performance of oxidized chitosan-crosslinked acellular porcine aorta modified with bioactive SCPP/DOPA for esophageal scaffold with enhanced mechanical strength, biocompatibility and anti-inflammatory. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, [PMID:37100332] [10.1016/j.ijbiomac.2023.124522] |
| 4. Hui-Zhen Zhang, Mei Shu, Wen-Yu Yang, Hong Pan, Men-Xuan Tang, Yuan-Yang Zhao, Chan Zhong, Guo-Ping Wu. (2022) Isolation and characterization of a novel Salmonella bacteriophage JNwz02 capable of lysing Escherichia coli O157:H7 and its antibacterial application in foods. LWT-FOOD SCIENCE AND TECHNOLOGY, [PMID:] [10.1016/j.lwt.2022.114251] |
| 5. Luan Zhaohui, Liu Shuang, Wang Wei, Xu Kaige, Ye Shaosong, Dan Ruijue, Zhang Hong, Shu Zhenzhen, Wang Tongchuan, Fan Chaoqiang, Xing Malcolm, Yang Shiming. (2022) Aligned nanofibrous collagen membranes from fish swim bladder as a tough and acid-resistant suture for pH-regulated stomach perforation and tendon rupture. Biomaterials Research, 26 (1): (1-20). [PMID:36348451] [10.1186/s40824-022-00306-1] |
| 6. Can Cheng, Xu Peng, Linjie Xi, Yihao Luo, Yuhang Wang, Yufan Zhou, Xixun Yu. (2022) Feasibility study of oxidized naringin as a novel crosslinking agent for crosslinking decellularized porcine Achilles tendon and its potential application for anterior cruciate ligament repair. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 111 (2): (170-184). [PMID:36054309] [10.1002/jbm.a.37440] |
| 7. Guangquan Hu, Xiaojie Ding, Feng Gao, Jiehua Li. (2022) Calcium and integrin binding protein 1 (CIB1) induces myocardial fibrosis in myocardial infarction via regulating the PI3K/Akt pathway. EXPERIMENTAL ANIMALS, [PMID:34349085] [10.1538/expanim.21-0063] |
| 8. Jiansheng Liu, Xueqin Qing, Qin Zhang, Ningyue Yu, Mengbin Ding, Zhaohui Li, Zhen Zhao, Zhiling Zhou, Jingchao Li. (2021) Oxygen-producing proenzyme hydrogels for photodynamic-mediated metastasis-inhibiting combinational therapy. Journal of Materials Chemistry B, 9 (26): (5255-5263). [PMID:34138994] [10.1039/D1TB01009C] |
| 9. Yu Luo, Shenyu Huang, Lie Ma. (2021) A novel detergent-based decellularization combined with carbodiimide crosslinking for improving anti-calcification of bioprosthetic heart valve. Biomedical Materials, 16 (4): (045022). [PMID:33979785] [10.1088/1748-605X/ac0088] |
| 10. Yu Luo, Lie Ma. (2020) Bioprosthetic heart valves with reduced immunogenic residuals using vacuum-assisted decellularization treatment. Biomedical Materials, 15 (6): (065012). [PMID:33016260] [10.1088/1748-605X/abaabf] |
| 11. Yu Luo, Dong Lou, Lie Ma, Changyou Gao. (2019) Optimizing detergent concentration and processing time to balance the decellularization efficiency and properties of bioprosthetic heart valves. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 107 (10): (2235-2243). [PMID:31125175] [10.1002/jbm.a.36732] |
| 12. Xuancheng Zhang, Zhaoyi Fang, Eunshinae Cho, Kai Huang, Jinzhong Zhao, Jia Jiang, Xiaoqiao Huangfu. (2019) Use of a Novel, Reinforced, Low Immunogenic, Porcine Small Intestine Submucosa Patch to Repair a Supraspinatus Tendon Defect in a Rabbit Model. Biomed Research International, [PMID:31073531] [10.1155/2019/9346567] |
| 13. Ma Liang, Guo Ting, Pan Shuli, Zhang Yuhao. (2018) A fluorometric aptasensor for patulin based on the use of magnetized graphene oxide and DNase I-assisted target recycling amplification. MICROCHIMICA ACTA, 185 (10): (1-6). [PMID:30276550] [10.1007/s00604-018-3023-z] |
| 14. Yuanting Xu, Chengcheng Huang, Li Li, Xixun Yu, Xu Wang, Hong Peng, Zhipeng Gu, Yaping Wang. (2013) In vitro enzymatic degradation of a biological tissue fixed by alginate dialdehyde. CARBOHYDRATE POLYMERS, [PMID:23618251] [10.1016/j.carbpol.2013.03.021] |
| 15. Yuanting Xu, Li Li, Hao Wang, Xixun Yu, Zhipeng Gu, Chengcheng Huang, Hong Peng. (2012) In vitro cytocompatibility evaluation of alginate dialdehyde for biological tissue fixation. CARBOHYDRATE POLYMERS, [PMID:23218319] [10.1016/j.carbpol.2012.09.096] |
| 16. Zongyou Jiang, Zhongzuo Huang, Yating Li, Xiaoxiao Yu, Yannan Ma, Jinyan Yu, Yifan Xiang, Yue Lv, Shaoqi Gao, Yicheng Luo, Bo Wang. (2024) A vascularized adipose organoid model using stromal vascular fraction cells from ruminant animals. STAR Protocols, [PMID:38635394] [10.1016/j.xpro.2024.103019] |
| 17. Jingyao Li, Huixi Yi, Yuanyuan Fu, Jiani Zhuang, Zhixiong Zhan, Liyou Guo, Ji Zheng, Xiyong Yu, Dong-Yang Zhang. (2024) Biodegradable iridium coordinated nanodrugs potentiate photodynamic therapy and immunotherapy of lung cancer. JOURNAL OF COLLOID AND INTERFACE SCIENCE, [PMID:39488900] [10.1016/j.jcis.2024.10.156] |
| 18. Zhoujiang Chen, Lianlin Long, Ji Wang, Mingli Jiang, Wei Li, Wenguo Cui, Liang Zou. (2024) Enhanced Tumor Site Accumulation and Therapeutic Efficacy of Extracellular Matrix-Drug Conjugates Targeting Tumor Cells. Small, [PMID:38829027] [10.1002/smll.202402040] |
| 19. Jingnan Li, Chengyan Luo, Tingyu Sun, Yinglin Zhou, Xinchang Huang, Dezhou Wu, Xirui Luo, Chao Zeng, Huanan Li. (2024) Hypoxia-Specific Metal–Organic Frameworks Augment Cancer Immunotherapy of High-Intensity Focused Ultrasound. ACS Nano, [PMID:38949962] [10.1021/acsnano.4c02921] |
| 20. yuke cen, Lin Zhang, Yue Jiang, Xiang-Fu Meng, Yuan Li, Chao Xiang, Ya-Ping Xue, Yu-Guo Zheng. (2024) Not exclusively the activity, but the sweet spot: a dehydrogenase point mutation synergistically boosts activity, substrate tolerance, thermo-stability and yield. ORGANIC & BIOMOLECULAR CHEMISTRY, [PMID:38529785] [10.1039/D4OB00211C] |
| 21. Shaofang Ma, Yan Zhang, Zihan Zhu, Deping Wang, Xin Zhou, Jing Wang, Wei Bian, Xinjing Tang. (2024) Nucleolus-Targeting Carbon Dot Nanocomplexes for Combined Photodynamic/Photothermal Therapy. MOLECULAR PHARMACEUTICS, [PMID:39895310] [10.1021/acs.molpharmaceut.4c01211] |
| 22. Xuan He, Dan Liang, Jun Zhou, Kangjing Li, Beibei Xie, Chunyun Liang, Cong Liu, Zhiyong Chen, Xinxin Chen, Ao Long, Shufang Zhuo, Xiaoping Su, Ying Luo, Wenxia Chen, Fengfeng Zhao, Xinglu Jiang. (2024) Nucleus-targeting DNase I self-assembly delivery system guided by pirarubicin for programmed multi-drugs release and combined anticancer therapy. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, [PMID:38608986] [10.1016/j.ijbiomac.2024.131514] |
| 23. Yu-Ke Cen, Lin Zhang, Meng-Ping Liu, Chao Xiang, Tao-Xu Lu, Ya-Ping Xue, Yu-Guo Zheng. (2025) Salt-driven dynamic folding of halophile-origin enzymes: Insights into evolution and protein exploitation. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, [PMID:39894131] [10.1016/j.ijbiomac.2025.140527] |
| 24. Zihan Zhu, Yan Zhang, Cui He, Yimin Jin, Wei Bian, Xinjing Tang, Jing Wang. (2025) Tumor microenvironment-responsive multinucleated nanocomplexes loaded with carbon dots for combined photothermal/chemodynamic therapy of breast cancer. ChemMedChem, [PMID:39821494] [10.1002/cmdc.202400983] |
| 25. Wang Linhai, Hu Xiao, Yao Guoqing, Chen Qinhua, Wang Sicen. (2024) Visual aptasensor based on PtNPs/g-C3N4 and DNase I for the field detection of acetamiprid. MICROCHIMICA ACTA, 191 (12): (1-10). [PMID:39499329] [10.1007/s00604-024-06801-7] |
| 26. Ma Xiao, Chen Jiao, Wang Fang, Fan Xinzou, Li Zhenhong, Liang Hantian, Cheng Hao, Nan Fang, Lin Yubin, Song Xiaoshuang, Zhang Jianan, Gao Fan, Zhang Wei, Jin Wenwen, Zhang Huiyuan, Tong Jiyu, Jiang Hong, Zhou Xikun, Zou Qiang, Hu Hongbo, Tong Aiping, Chen WanJun, Zhang Dunfang. (2025) High fructose consumption aggravates inflammation by promoting effector T cell generation via inducing metabolic reprogramming. Signal Transduction and Targeted Therapy, 10 (1): (1-20). [PMID:40854873] [10.1038/s41392-025-02359-9] |
| 27. Honglin Li, Yanwen Feng, Bingyan Lin, Shiqiang Zhang, Yijin Ren, Jun Yue. (2025) Polyurea-based multimodal interaction nanogels for synergistic bacterial biofilm eradication and prevention of re-colonization. BIOMATERIALS, [PMID:40782449] [10.1016/j.biomaterials.2025.123607] |
| 28. Yi Lu, Yibo Shan, Jianwei Zhu, Zhiming Shen, Wenxuan Chen, Hao Chen, Hongcan Shi. (2024) Enhancing epithelial regeneration with gelatin methacryloyl hydrogel loaded with extracellular vesicles derived from adipose mesenchymal stem cells for decellularized tracheal patching.. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, [PMID:39603308] [10.1016/j.ijbiomac.2024.137927] |
| 29. Yang Wang, Guangzhe Li, Jianlong Su, Yiming Liu, Xiaomai Zhang, Guanyi Zhang, Zhihao Wu, Jinrong Li, Yuxuan Zhang, Xu Wang, Zejia Yang, Ruimin Wang, Chengdong Wang, Liu Wang, Fangfang Sun, Weijie Zhao, Xuejian Wang, Xiaojun Peng, Kun Shao. (2024) Spatiotemporal Controllable Sono-Nanovaccines Driven by Free-Field Based Whole-Body Ultrasound for Personalized Cancer Therapy. Advanced Science, [PMID:38308196] [10.1002/advs.202307920] |
| 30. Hua Chai, Renpeng Xia, Nan Ouyang, Jingyu Yao, Jiukun Hu, Minxuan Sun, Peng Miao. (2025) Membrane Encapsulated Fe3O4@MnO@cGAMP Nanocatalyst for Cancer Therapy: cGAS-STING Immune Pathway Activation. Advanced Healthcare Materials, [PMID:40231491] [10.1002/adhm.202501587] |
| 31. Zihan Zhu, Yan Zhang, Lianggan Luo, Xuan Shang, Xinli Fan, Wei Bian, Jing Wang, Xinjing Tang. (2025) Salivary acid-modified carbon dots loaded with paclitaxel for imaging-guided combination treatment of breast cancer. Biomaterials Science, [PMID:40539237] [10.1039/D5BM00139K] |
| 32. Miao Zhang, Shan Gao, Nannan Tan, Yu Yan, Rongxin Zhu, Jiajing Liu, Qin Mao, Keyan Wang, Wenhao Zhang, Gang Wang, Zhuo Wang, Tieshan Wang, Xueshi Huang, Rong Zhang, Baofeng Yang. (2025) 13-methylpalmatine alleviates myocardial ischemia/reperfusion injury by potentially targeting the C5a-C5aR1 axis to inhibit neutrophil extracellular trap formation. Redox Biology, [PMID:40768896] [10.1016/j.redox.2025.103802] |
| 33. Gu Xinyi, Huang Chen, Wang Shen, Deng Jin, Guo Shuhang, Yin Xiaofeng. (2025) Inductive analysis of the spatial distribution characteristics of neurons that innervate skeletal muscle and their correlation with muscle phenotype. Neural Regeneration Research, [PMID:40817724] [10.4103/NRR.NRR-D-24-01540] |
| 34. Mo Fei, Hong Min, Chen Xiao, Wang Qiye, Dong Chao. (2025) Genistein enhances anti-PD-1 efficacy in melanoma by suppressing regulatory T cell differentiation and activity. Scientific Reports, 15 (1): (1-10). [PMID:41125717] [10.1038/s41598-025-20941-7] |
| 35. Yating Li, Jianrong Huo, Shilong Yu, Yifan Xiang, Yanrong Feng, Zongyou Jiang, Shaoqi Gao, Zhongzuo Huang, Yichen Luo, Yu Xin, Jinyan Yu, Bo Wang, Junxing Zhao. (2025) Maternal Taurine Supplementation Enhances Thermogenesis of Newborn Lambs by Promoting Brown Adipogenesis. FASEB JOURNAL, 39 (20): (e71185). [PMID:41139244] [10.1096/fj.202502140RR] |
| 36. Huan Cong, Xuejing Hou, Shasha Wang, Jie Pang, Anhua Wang, Kuo Zhang, Jingyu Yang, Chunfu Wu. (2025) Tectoridin Derived from Puerariae Flos Alleviates Acute Ethanol-Induced Ataxia in Rats by Targeting the Adenosine A1 Receptor via Its Aglycone. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, [PMID:41328621] [10.1021/acs.jafc.5c09262] |
| 37. Ge Xiaolu, Yu Liang, Zhang Lei, Jia Liqing, Meng Mingjing, He Jingquan, Bu Fan, Song Yue, Sun Gaorui, Lv Shiming, Mei Desheng, Yang Yutao, Xu Dakang, Zhang Jingfa, Zhang Shengping, Wang Chuangui, Jia Deshui, Chen Yongping, Gao Yue, He Baokun. (2025) Targeting LRBA triggers CTLA4 degradation and antitumor immunity for cancer immunotherapy. Nature Communications, [PMID:41390689] [10.1038/s41467-025-67365-5] |
| 38. Liqin Xie, Tianyi Zeng, Dan Li, Wenke Chang, Shenglu Ji, Zichun Hua. (2026) Superparamagnetic Fe3O4 nanoclusters for cancer therapy and metastasis prevention via synergistic chemotherapy and NETs degradation. Biomaterials Advances, [PMID:41529527] [10.1016/j.bioadv.2026.214709] |
| 39. Chunjiao Zheng, Wei Li, Yuanyuan Wang, Lulu Li, Linan Ni, Xiaoping Liu, Jingwen Tan, Lianjuan Yang, Qian Yu. (2026) Tricyclazole alleviates Fonsecaea pedrosoi-induced immune suppression of neutrophils by inhibiting DHN-melanin biosynthesis. Frontiers in Cellular and Infection Microbiology, [PMID:41602105] [10.3389/fcimb.2025.1697287] |
| 40. Yuhan Wang, Pengfei Diao, Pin Lv, Na Qi, Ziyu Wang, Enshi Yan, Jin Li, Yanling Wang, Dongmiao Wang, Yaping Wu, Jie Cheng. (2026) A human patient-derived organoid biobank to model tumor heterogeneity and therapeutic vulnerability for oral squamous cell carcinoma. Cell Reports Medicine, 7 (2): [PMID:41707653] [10.1016/j.xcrm.2026.102622] |
| 41. Qiulian Mao, Hui Cai, Mei Chen, Ang Xiao, Haorong Jiao, Fang Jia, Jicun Ma, Jiada Fan, Jing Liu, Kangbo Zhang, Xinyue Wu, Yilin Liu, Jiabin Cui, Wei-Hai Chen. (2026) Reprogramming the Tumor Mechanical Microenvironment with Lactate Inhibition and Stimulator of Interferon Genes Activation to Potentiate Systematic Radio-Immunotherapy. ACS Nano, [PMID:41693666] [10.1021/acsnano.5c16809] |
| 42. Chenchen Hu, Feiming Hu, Changjian Shao, Yuanli He, Liping Su, Daimei Shi, Lingying Yu, Yuanjie Sun, Jing Wang, Xiyang Zhang, Hongtao Duan, Junqi Zhang, Yubo Sun, Dongbo Jiang, Xiaolong Yan, Shuya Yang, Kun Yang. (2026) TIMELESS Promotes LUAD Growth via Suppressing Transferrin-Mediated Ferroptosis and Reprograms the Tumor Microenvironment against Anti-PD-1 Immunotherapy. Cancer Communications, [PMID:41641368] [10.34133/cancomm.0009] |
| 43. Liping Cai, Qing Zhang, Tianxiong Yao, Xiaoxiao Zou, Lei Xie, Siyu Yang, Yanyuan Xiao, Fei Huang, Zhiwei Peng, Jiawen Yang, Jianzhen Huang, Qiqi Jing, Ziqi Ling, Min Zheng, Chuanmin Qiao, Jinyuan Wu, Jiaqi Chen, Tao Jiang, Qin Liu, Min Liu, Zhe Chen, Jingquan Li, Hui Jiang, Haoyun Jiang, Zuoquan Chen, Yaya Liao, Yizhong Huang, Longyun Li, Yunyan Zhou, Zhou Zhang, Chao Yin, Yu Ye, Hui Yang, Biao Chen, Zhong Wang, Huanfa Gong, Dong Chen, Cong Huang, Xinkai Tong, Zhimin Zhou, Hao Fu, Yingchun Sun, Xiao Sun, Min Yan, Lin Wu, Shuqi Xiong, Yaxiang Wang, Xinke Xie, Mengqing Zhou, Xiaodong Liu, Xianhua Xie, Fusheng Wu, Zifeng Liu, Mei Ge, Sanya Xiong, Chenyu Li, Tao Shen, Yuxin Liu, Xi Tang, Xiaolong Chang, Siyi Liu, Chuangang Yu, Naixiang Yu, Zikang Hu, Dengshuai Cui, Jiahong Zhong, Sha Liu, Jianchao Hu, Yang Wen, Weiwei Zhou, Guanyue Wei, Shiyao Lin, Yiwen Xiahou, Liqing Chen, Jianjun Li, Ruirong Liu, Xiaoyun Chen, Yujie Shu, Feng Chen, Chao Wei, Xiaofen Hu, Yong Li, Yong Hou, Qingjie Zeng, Jun Gao, Ying Su, Jing Li, Junwu Ma, Yuanmei Guo, Congying Chen, Shijun Xiao, Huashui Ai, Zhiyan Zhang, Weiwei Liu, Qiang Yang, Yuyun Xing, Lin Rao, Bin Yang, Lusheng Huang. (2026) Family single-cell atlases reveal pig pregnancy and fetal growth restriction critical cell types. SCIENCE, 391 (6792): [PMID:41886583] [10.1126/science.adu7265] |
Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.
View Recombinant grade guide → View EnzymoPure™ grade guide →