Antibo-drug conjugate (ADCs) combines the high specificity of antibodies with the strong cytotoxicity of small-molecule drugs. This combination combines the antibody's unique and very sensitive targeting ability to distinguish between healthy and cancerous tissue. It also has the cell-killing ...
BINOL and its derivatives are one of the most widely used types of ligands in asymmetric synthesis; being utilized in a variety of reactions including——Diels-Alder, carbonyl addition and reduction, Michael addition, and a variety of other reactions. Although great success has been achieved ...
Click chemistry is a new approach to synthesizing drug-like molecules that can accelerate the drug discovery process by utilizing a number of practical and reliable reactions. Chemist K B Sharpless and colleagues define a click reaction as one that is wide-ranging, easy to perform, uses only ...
Macrophage stimulating protein (MSP) is a protein produced by macrophages. Macrophages play a variety of roles in the immune defense system, including a central role in innate or natural immunity, and were first described as phagocytes by Metchnikoff in the 19th century, and are now known to ...
Hyaluronic acid (HA) is the simplest glycosaminoglycan (a class of negatively charged polysaccharides) and a major constituent of the extracellular matrix (ECM). Hyaluronan is a scaffold secreted by cells that surrounds them in vivo, HA is a linear, non-sulfated polysaccharide that provides ...
Aladdin's liposome is a widely studied nano drug carrier in the current drug delivery system. It is a closed vesicle composed of lipid bilayer composed of phospholipids and cholesterol.
IgG, the key factor of Humoral immunity response, is the main immunoglobulin in blood, lymph, cerebrospinal fluid and peritoneal fluid. IgG accounts for approximately 75% of total serum immunoglobulins and is the only immunoglobulin that can penetrate the human placenta. It is primarily ...
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