Gelsolin Mouse mAb - Primary antibody, specific to Gelsolin, Mouse IgG1
mAb (D1); Mouse anti Human Gelsolin Antibody; WB, IHC; Unconjugated
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mAb (D1); Mouse anti Human Gelsolin Antibody; WB, IHC; Unconjugated
Mouse anti Human Gelsolin Antibody, Monoclonal (D1), could be used for WB, IHC and so on.
Application
WB: 0.01-3 µg/mL
IHC: 5-20 μg/mL
Protein Function
Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis.
| Objetivo | GSN |
|---|---|
| Clon | D1 |
| Identificación genética | 2934 |
| Número de adhesión | P06396 |
| Símbolo genético | GSN |
| Sinónimos | Actin-depolymerizing factor | ADF | AGEL | Brevin | DKFZp313L0718 | gelsolin (amyloidosis, Finnish type) | Gelsolin | GSN | Actin depolymerizing factor antibody | Actin-depolymerizing factor antibody | ADF antibody | AGEL antibody | Brevin antibody | DKFZ |
| Especificaciones y pureza | Carrier Free, ExactAb™, Validated, High Performance, See COA |
| Especificidad | Gelsolin |
| Inmunógeno | Recombinant GSN expressed in E.coli (AA 434-782). |
| Epítopo | The antibody is directed against an epitope located on the 47 kD peptide derived from a chymotryptic cleavage of gelsolin. This peptide contains the carboxy terminal actin binding site for gelsolin. |
| Control positivo | WB: Human serum, A549, HeLa and C6 lysates. IHC: Human kidney and colon tissues. |
| Isotipo | Mouse IgG1 |
| Tipo de cadena ligera | kappa |
| SDS-PAGE | 150 kDa |
| Método de purificación | Protein A + Protein G purified |
| Concentración | See COA |
| Product Description | Mouse anti Human Gelsolin Antibody, Monoclonal (D1), could be used for WB, IHC and so on. |
| Forma | Liquid |
| Condiciones de almacenamiento de almacenamiento | Store at -20°C,Avoid repeated freezing and thawing |
| Enviado en | Ice chest + Ice pads |
| Estabilidad y almacenamiento | Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |