Guselkumab (anti-IL-23) - Primary antibody, specific to IL23A, >95%, Human IgG1, INHIBITOR of Interleukin-23 inhibitor, INHIBITOR of Interleukin-23 inhibitor

CAS: 1350289-85-8 Cat. No.: Ab175717
Disponible para pedir
GRADE & PURITY Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA
Application
Animal Model, ELISA, Flow Cytometry, Functional Assay
Host species
Human
Reactive species
Cynomolgus monkey, Human
Isotype
Human IgG1
Conjugation
Unconjugated
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
100μg
Ab175717-100μg
10
243,90US$
1mg
Ab175717-1mg
5
1.214,90US$
5mg
Ab175717-5mg
1
5.225,90US$
10mg
Ab175717-10mg
1-2 wks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
8.361,90US$
Enter a quantity for the sizes you want to add.
🧪

Why this grade

Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA Animal Free,Azide Free,Carrier Free,ExactAb™,Low Endotoxin,Recombinant,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C,Avoid repeated freezing and thawing Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Guselkumab (anti-IL-23) is a recombinant human IgG1 monoclonal antibody against the IL-23p19 subunit. Guselkumab (anti-IL-23) binds to human and cynomolgus monkey IL-23 with Kd values of 3.3 and 1.9 pmol/L, respectively. Guselkumab (anti-IL-23) inhibits production of cytokines lying downstream of the IL-23 signaling pathway and can be used for psoriatic arthritis research.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Specifications

Product Name
Guselkumab (anti-IL-23) - Primary antibody, specific to IL23A, >95%, Human IgG1, INHIBITOR of Interleukin-23 inhibitor
Sinónimos
IL 23 A antibody | IL 23 antibody | IL 23 subunit alpha antibody | IL 23A antibody | IL 23p19 antibody | IL-23 subunit alpha antibody | IL-23-A antibody | IL-23p19 antibody | IL12B antibody | IL23 antibody | Il23a antibody | IL23A_HUMAN antibody | IL23P19
Especificaciones y pureza
Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Especies hospedadoras
Human
Especificidad
IL23A
Conjugación
Unconjugated
Grado
Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Tipo de acción
INHIBITOR
Mecanismo de acción
INHIBITOR of Interleukin-23 inhibitor
Isotipo
Human IgG1
Tipo de cadena ligera
lambdaC2
SDS-PAGE
27.8 kDa (Light Chain) & 50.7 kDa (Heavy Chain), under reducing conditions; 170.7 kDa, under non-reducing conditions.
Método de purificación
Protein A purified
Pureza
>95%
Concentración
See COA
CAS
1350289-85-8
Almacenamiento y envío
Forma
Liquid
Condiciones de almacenamiento de almacenamiento
Store at -80°C,Avoid repeated freezing and thawing
Enviado en
Dry ice packs + Cold packs
Estabilidad y almacenamiento
Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Imágenes

Guselkumab (anti-IL-23) (Ab175717) - SEC
The purity of Guselkumab (anti-IL-23) (Ab175717) is more than 95% verified by HPLC.

Guselkumab (anti-IL-23) (Ab175717) - ELISA
Immobilized IL-23 at 2 μg/mL can bind Guselkumab (anti-IL-23) (Ab175717) with the EC₅₀ of 16.45 ng/mL.

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Objetivos asociados (humanos)
IL23A Tclin Interleukin-23 subunit alpha (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot NumberCertificate TypeFechaArticulo
ZJ23F1202000Certificate of AnalysisDec 13, 2023 Ab175717
ZJ23F1201999Certificate of AnalysisDec 13, 2023 Ab175717
Calculadoras de soluciones
Reseñas

Reseñas de cliente

Need help choosing the grade?

Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

View Animal Free grade guide → View Carrier Free grade guide → View Recombinant grade guide → View Validated grade guide → View ExactAb™ grade guide → View Low Endotoxin grade guide → View Azide Free grade guide →

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