HATU - ≥99% , CAS No.148893-10-1

CAS: 148893-10-1 Cat. No.: H109327 Peso molecular: 380.23 Número EC: 604-662-7 PubChem CID: 9886157
Disponible para pedir
GRADE & PURITY ≥99%
Synonyms
HATU | 2-(7-Aza-1H-Benzotriazole -1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate | MFCD00274639 | 0-(7-Azabenzotriazol-1-yl)-N,N, N',N'-tetramethyluronium hexafluorophosphate | NSC 165796 | SCHEMBL63612 | 0-(7-Azabenzotriazol-1-yl)-N,N,N',N'-tetrame
Storage
Store at 2-8°C,Argon charged
Shipped In
Wet ice
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
1g
H109327-1g
5
9,90US$
5g
H109327-5g
2
10,90US$
10g
H109327-10g
3

11,90US$

17,90US$
Guardar 6,00 US$ (33.52%)
25g
H109327-25g
1

21,90US$

32,90US$
Guardar 11,00 US$ (33.43%)
100g
H109327-100g
2

65,90US$

98,90US$
Guardar 33,00 US$ (33.37%)
500g
H109327-500g
2

273,90US$

410,90US$
Guardar 137,00 US$ (33.34%)
Enter a quantity for the sizes you want to add.
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Why this grade

≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C,Argon charged Ships Wet ice Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 111 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

HATU is useful as a peptide coupling agent and a catalyst for selective acylation. It is also a reagent for reactions involving amide bond formations.

Specifications

Sinónimos
HATU | 2-(7-Aza-1H-Benzotriazole -1-yl)-1, 1, 3, 3-tetramethyluronium hexafluorophosphate | MFCD00274639 | 0-(7-Azabenzotriazol-1-yl)-N, N, N', N'-tetramethyluronium hexafluorophosphate | NSC 165796 | SCHEMBL63612 | 0-(7-Azabenzotriazol-1-yl)-N, N, N', N'-tetrame
Especificaciones y pureza
≥99%
Condiciones de almacenamiento de almacenamiento
Store at 2-8°C, Argon charged
Enviado en
Wet ice
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Pureza
≥99%
Nombres e identificadores
Sonrisas canónicasCN(C)C(=[N+](C)C)ON1C2=C(C=CC=N2)N=N1.F[P-](F)(F)(F)(F)F
IUPAC Name[dimethylamino(triazolo[4,5-b]pyridin-3-yloxy)methylidene]-dimethylazanium;hexafluorophosphate
InChIKeyJNWBBCNCSMBKNE-UHFFFAOYSA-N
INCHI1S/C10H15N6O.F6P/c1-14(2)10(15(3)4)17-16-9-8(12-13-16)6-5-7-11-9;1-7(2,3,4,5)6/h5-7H,1-4H3;/q+1;-1
Isómeros SMILES CN(C)C(=[N+](C)C)ON1C2=C(C=CC=N2)N=N1.F[P-](F)(F)(F)(F)F
WGK Alemania 3
PubChem CID 9886157
Peso molecular 380.23
Reaxy-Rn 11805773

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClaseTriazolopyridines
SubclassNot available
Intermediate Tree Nodes Not available
Direct ParentTriazolopyridines
Alternative Parents Pyridines and derivatives  Triazoles  Heteroaromatic compounds  Propargyl-type 1,3-dipolar organic compounds  Carboximidic acids and derivatives  Carboximidamides  Azacyclic compounds  Organopnictogen compounds  Organooxygen compounds  Organic salts  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents Triazolopyridine - Pyridine - Azole - 1,2,3-triazole - Heteroaromatic compound - Carboximidic acid derivative - Carboximidamide - Propargyl-type 1,3-dipolar organic compound - Organic 1,3-dipolar compound - Azacycle - Hydrocarbon derivative - Organopnictogen compound - Organic oxygen compound - Organic nitrogen compound - Organonitrogen compound - Organic salt - Organooxygen compound - Aromatic heteropolycyclic compound
DescripciónThis compound belongs to the class of organic compounds known as triazolopyridines. These are compounds containing a triazole ring fused to a pyridine ring. Triazole is a five-membered ring consisting of two carbon atoms and three nitrogen atoms. Pyridine is a 6-membered ring consisting of five carbon atoms and one nitrogen center.
External Descriptors Not available
Estructura 3D
Modelo de Estructura Química Interactiva





Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

36 results found

Lot NumberCertificate TypeFechaArticulo
L2518379Certificate of AnalysisNov 27, 2025 H109327
L2518366Certificate of AnalysisNov 27, 2025 H109327
L2518367Certificate of AnalysisNov 27, 2025 H109327
L2518368Certificate of AnalysisNov 27, 2025 H109327
E2414085Certificate of AnalysisApr 28, 2024 H109327
E2414086Certificate of AnalysisApr 28, 2024 H109327
E2512038Certificate of AnalysisApr 28, 2024 H109327
E2522078Certificate of AnalysisApr 28, 2024 H109327
E2414084Certificate of AnalysisApr 28, 2024 H109327
E2414083Certificate of AnalysisApr 28, 2024 H109327
K2428180Certificate of AnalysisApr 28, 2024 H109327
J2527154Certificate of AnalysisApr 28, 2024 H109327
G2501084Certificate of AnalysisApr 28, 2024 H109327
G2521025Certificate of AnalysisApr 28, 2024 H109327
H2528097Certificate of AnalysisApr 28, 2024 H109327
I2306491Certificate of AnalysisJul 24, 2023 H109327
I2306494Certificate of AnalysisJul 24, 2023 H109327
I2306493Certificate of AnalysisJul 24, 2023 H109327
I2306492Certificate of AnalysisJul 24, 2023 H109327
L2209715Certificate of AnalysisNov 01, 2022 H109327
G2304038Certificate of AnalysisNov 01, 2022 H109327
L2209617Certificate of AnalysisNov 01, 2022 H109327
L2209611Certificate of AnalysisNov 01, 2022 H109327
L2209575Certificate of AnalysisNov 01, 2022 H109327
L2209608Certificate of AnalysisNov 01, 2022 H109327
K2205235Certificate of AnalysisOct 27, 2022 H109327
K2205236Certificate of AnalysisOct 27, 2022 H109327
J2217630Certificate of AnalysisSep 30, 2022 H109327
H1830097Certificate of AnalysisJun 24, 2022 H109327
G2201311Certificate of AnalysisJun 04, 2022 H109327
G2201312Certificate of AnalysisJun 04, 2022 H109327
G2201310Certificate of AnalysisJun 04, 2022 H109327
G2201309Certificate of AnalysisJun 04, 2022 H109327
G2201308Certificate of AnalysisJun 04, 2022 H109327
D2228160Certificate of AnalysisMar 09, 2022 H109327
D2228163Certificate of AnalysisMar 09, 2022 H109327

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Propiedades químicas y físicas
SolubilidadSoluble in Acetone and DMSO
SensibilidadHeat Sensitive,Hygroscopic
Punto de fusión (°C)183-186°C
Peso molecular380.230 g/mol
XLogP3
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count11
Rotatable Bond Count3
Exact Mass380.095 Da
Monoisotopic Mass380.095 Da
Topological Polar Surface Area59.100 Ų
Heavy Atom Count24
Formal Charge0
Complexity351.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count2
Preguntas frecuentes y artículos
Fluid chemistry: Lighting the fire of hope for the large-scale production of anticancer drugs
A bridge to protein science——Aladdin@Polypeptide
Solid-Phase Peptide Synthesis (SPPS) — Efficient Strategies and Innovative Techniques
A Complete Guide to Choosing Resins for SPPS (Solid-Phase Peptide Synthesis): Fmoc/Boc Routes, C-Terminal Acid/Amide, and a Key-Parameter Navigator
From Piperidine to Pyridine: The “Most Common N-Heterocycle” Shift in FDA Small-Molecule New Drugs (2013–2023) and a Selection Guide (Tables 1–4)
β-Acyloxy Alkenyl Amides (AAAs): A New Approach to Amide Bond and Peptide Bond Construction Worth Attention
DAST-Mediated Amidation at Room Temperature: Method Features, Practical Value, and Scope of Applicability
From High Reactivity to Comprehensive Evaluation: Using CTSOAt as an Example to Understand the Design Logic of New Coupling Reagents
From Analytical Instrument to Synthetic Platform: A New Strategy for Reconstructing Automated Flow Solid-Phase Peptide Synthesis with Standard Analytical HPLC
New Progress in the Solid-Phase Synthesis of Sterically Hindered Peptides: Background, Core Breakthroughs, and Implications for Automation Compatibility of the RMMR Strategy
TCFH–NMI Amidation in Highly Aqueous Media: Research Value, Methodological Understanding, and Experimental Insights
A New Balance in Coupling Reagents: How DMT-TU Balances Reactivity, Racemization Control, and Thermal Hazard
The Positioning of TBTU in Practice: Racemization Risk, Extended Uses, and Selection Criteria
From “High Yield” to “Configuration Retention”: Activation-Stage Risks, Route Differences, and Selection Principles for Coupling Systems
The Methodological Value of HATU in Difficult Couplings: Reactivity Advantages, Stereochemical Retention, and Condition Management
The Methodological Value of Boc-Oxyma: Low-Racemization Coupling, Route Continuity, and Extended Applications
Low Racemization in Peptide Synthesis Is Not Just About Reagent Choice: Stereochemical Risk During the Activation Stage and Practical Strategies for Experimental Control
The Methodological Value of TCFH: Advantages in Challenging Amidation and the Switching Logic of Carboxylic Acid Activation Pathways
Ynamide Coupling Reagents: From Low-Epimerization Activation Pathways to More Practically Usable N→C Inverse Peptide Synthesis
Decision Logic for Peptide Synthesis Routes: Applicability and Criteria for Choosing among SPPS, LPPS, and Recombinant Expression
Decision Logic for Selecting Coupling Reagents in Amide Bond Formation: Activation Pathways, Side Reactions, Epimerization, Workup, and Safety
Experimental Judgment in Oxyma Coupling Systems: Coupling Efficiency, Racemization Control, and the HCN Risk in DIC-Based Systems
Experimental Judgment for CMPI in Carboxylic Acid Activation: Applicable Tasks, Base Matching, and Workup Burden
Experimental Judgment for TFPN in Carboxylic Acid Activation: Suitable Scenarios, Intermediate Distribution, and Nucleophile Compatibility
Reaction Selection in Small-Molecule Synthesis: From Transformation-Type Assessment to Experimental Route Screening
How to Determine Whether a Protein Is Suitable for Targeted Degradation: From Degradation Pathway and Molecular Design to Mechanism Validation
How to Troubleshoot Abnormal Impurities in Peptide Synthesis? Locating Process Issues Through Amino-Related Side Reactions
Peptide Intermediates Difficult to Dissolve and Separate? Route Design and Workup Strategies for Tag-Assisted Liquid-Phase Peptide Synthesis (TAG-LPPS)
Citations of This Product
Referencias
1. Fangyuan Guo, Yunlong Jiao, Wenqin Ding, Yinzhou Du, Shuai Luo, Mengqi Wang, Yujia Wang, Fang Wu, Lianyi Wang, Gensheng Yang.  (2023)  Synergistic effects of multidrug/material combination deliver system for anti-mutidrug-resistant tumor.  INTERNATIONAL JOURNAL OF PHARMACEUTICS,      [PMID:38056797] [10.1016/j.ijpharm.2023.123669]
2. Xiaoxiao Gu, Haoyang Yuan, Cailing Li, Lixian Xu, Shuang Li, Dinghua Yu.  (2023)  Toluidine blue O photosensitizer combined with caffeic acid improves antibacterial performance by increasing the permeability of cell membrane.  COLLOIDS AND SURFACES B-BIOINTERFACES,      [PMID:38000122] [10.1016/j.colsurfb.2023.113657]
3. Yang Jingxuan, Guo Wenjun, Xu Xiaohang, Zhao Liang, Xu Yajuan, Wang Yang.  (2023)  Analysis of Fatty Acid in Biological Samples Using Liquid Chromatography–Quadrupole-Orbitrap Mass Spectrometry Under Parallel Reaction Monitoring Mode.  Journal of Analysis and Testing,      [PMID:] [10.1007/s41664-023-00286-8]
4. Panpan Qi, Quankuo He, Junjie Zhang, Yuanyuan Lian, Ting Xie, Jianying Dong, Dongting Zhangsun, Yong Wu, Sulan Luo.  (2023)  Enhancing Stability and Albumin Binding Efficiency of α-Conotoxin GI through Fatty Acid Modification.  BIOCHEMISTRY,      [PMID:37967580] [10.1021/acs.biochem.3c00385]
5. Jiaqi Cui, Jianxun Zhang, Shihao Sun, Wu Fan, Hui Xi, Xiujuan Xu, Lingbo Ji, Shusheng Zhang, Dingzhong Wang, Wuduo Zhao.  (2023)  Rapid and sensitive determination of free fatty acids based on in-source microdroplet-driven derivatization coupled with high-resolution mass spectrometry.  ANALYTICA CHIMICA ACTA,      [PMID:37709460] [10.1016/j.aca.2023.341717]
6. Yuan Lin, Yimin Zhang, Zhuang Xiong, Min Wu, Muling Zeng, Chuangnan Li, Fujin Liu, Yazhi Liao, Chunping Liu, Jing Chen.  (2023)  Development of glycyrrhetinic acid ligand-functionalized liposomes for targeting hepatocellular carcinoma: Synthesis, preparation, characterization, and evaluation.  Arabian Journal of Chemistry,      [PMID:] [10.1016/j.arabjc.2023.105131]
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14. Qingqing Yao, Jiahuan Chen, Xuechao Li, Wen Yang, Jianan Ning, Qi Liang, Qian Li.  (2022)  Site-selective covalent immobilization of PPARγ using a label-free strategy for chromatographic study.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2022.108278]
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18. Yu-Ming Fang, Qi-Lei Zhang, Dong-Qiang Lin, Shan-Jing Yao.  (2022)  One kind of challenging tetrapeptide biomimetic chromatographic resin for antibody separation.  JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES,      [PMID:35964489] [10.1016/j.jchromb.2022.123407]
19. Yong-Yuan Chen, Jin-Gang Yu.  (2022)  Nitrogen-containing graphene oxide composite with acid resistance and high adsorption selectivity for Nd3+.  Journal of Environmental Chemical Engineering,      [PMID:] [10.1016/j.jece.2022.108348]
20. Lei Hou, Yunchang Zhang, Ying Huang, Zhen Fang, Guangze Sang, Tianheng Chen, Zhiqiang Ma, Feng Yang.  (2022)  Coupling Chlorin-Based Photosensitizers and Histone Deacetylase Inhibitors for Photodynamic Chemotherapy.  MOLECULAR PHARMACEUTICS,      [PMID:35758904] [10.1021/acs.molpharmaceut.2c00170]
21. Mengting Li, Dongqiang Lin, Shanjing Yao, Qilei Zhang.  (2022)  Study on antibody adsorption and elution performance of carboxyl and hydrophobic groups on mixed-mode ligands.  JOURNAL OF SEPARATION SCIENCE,  45  (15): (2946-2955).  [PMID:35716379] [10.1002/jssc.202200342]
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39. Yang Li, Yimin Niu, Jianhua Zhu, Cuicui Gao, Qunwei Xu, Zhiyu He, Dawei Chen, Ming Xu, Yang Liu.  (2020)  Tailor-made legumain/pH dual-responsive doxorubicin prodrug-embedded nanoparticles for efficient anticancer drug delivery and in situ monitoring of drug release.  Nanoscale,  12  (4): (2673-2685).  [PMID:31942900] [10.1039/C9NR08558K]
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46. Hong-Yun Zhu, Sheng-Gang Chen, Qilei Zhang, Dong-Qiang Lin, Shan-Jing Yao.  (2019)  Adsorption Characteristics of Human Immunoglobulin G on Five New Tetrapeptide Biomimetic Affinity Resins.  JOURNAL OF CHEMICAL AND ENGINEERING DATA,      [PMID:] [10.1021/acs.jced.8b01199]
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50. Wei Wei, Cong Luo, Jincheng Yang, Bingjun Sun, Dongyang Zhao, Yan Liu, Yingli Wang, Wenqian Yang, Qiming Kan, Jin Sun, Zhonggui He.  (2018)  Precisely albumin-hitchhiking tumor cell-activated reduction/oxidation-responsive docetaxel prodrugs for the hyperselective treatment of breast cancer.  JOURNAL OF CONTROLLED RELEASE,      [PMID:30017721] [10.1016/j.jconrel.2018.07.010]
51. Xiaojing Su, Hongqiang Li, Xuejun Lai, Zhipeng Yang, Zhonghua Chen, Wenjian Wu, Xingrong Zeng.  (2018)  Vacuum-assisted layer-by-layer superhydrophobic carbon nanotube films with electrothermal and photothermal effects for deicing and controllable manipulation.  Journal of Materials Chemistry A,  (35): (16910-16919).  [PMID:] [10.1039/C8TA05273E]
52. Shasha He, Chan Li, Qingfei Zhang, Jianxun Ding, Xing-Jie Liang, Xuesi Chen, Haihua Xiao, Xiaoyuan Chen, Dongfang Zhou, Yubin Huang.  (2018)  Tailoring Platinum(IV) Amphiphiles for Self-Targeting All-in-One Assemblies as Precise Multimodal Theranostic Nanomedicine.  ACS Nano,      [PMID:29906087] [10.1021/acsnano.8b03476]
53. Shuailing Huang, Yinglong Wu, Fang Zeng, Junjie Chen, Shuizhu Wu.  (2018)  A turn-on fluorescence probe based on aggregation-induced emission for leucine aminopeptidase in living cells and tumor tissue.  ANALYTICA CHIMICA ACTA,      [PMID:30119736] [10.1016/j.aca.2018.05.032]
54. Qingzhi Lv, Jincheng Yang, Ruoshi Zhang, Zimeng Yang, Zhengtao Yang, Yongjun Wang, Youjun Xu, Zhonggui He.  (2018)  Prostate-Specific Membrane Antigen Targeted Therapy of Prostate Cancer Using a DUPA–Paclitaxel Conjugate.  MOLECULAR PHARMACEUTICS,      [PMID:29608845] [10.1021/acs.molpharmaceut.8b00026]
55. Yiwen You, Zhiyuan Xu, Yun Chen.  (2018)  Doxorubicin conjugated with a trastuzumab epitope and an MMP-2 sensitive peptide linker for the treatment of HER2-positive breast cancer.  DRUG DELIVERY,      [PMID:29405790] [10.1080/10717544.2018.1435746]
56. Zhaojie Wang, Yuanhao Qiu, Chunyan Hou, Dongdong Wang, Feifei Sun, Xiaojun Li, Feng Wang, Hong Yi, Haibo Mu, Jinyou Duan.  (2017)  Synthesis of hyaluronan-amikacin conjugate and its bactericidal activity against intracellular bacteria in vitro and in vivo.  CARBOHYDRATE POLYMERS,      [PMID:29253955] [10.1016/j.carbpol.2017.10.061]
57. Caihong Li, Jian Li, Xiaodi Yang, Ling Gao, Lijun Jing, Xiaoling Ma.  (2016)  A label-free electrochemical aptasensor for sensitive myoglobin detection in meat.  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2016.09.087]
58. Rong-Zhu Wang, Dong-Qiang Lin, Wen-Ning Chu, Qi-Lei Zhang, Shan-Jing Yao.  (2016)  New tetrapeptide ligands designed for antibody purification with biomimetic chromatography: Molecular simulation and experimental validation.  BIOCHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.bej.2016.06.030]
59. Changyu He, Zhen Zhang, Qinglai Yang, Qing Chang, Zhifeng Shao, Bing Gong, Yu-Mei Shen, Bingya Liu, Zhenggang Zhu.  (2016)  Reductive triblock copolymer micelles with a dynamic covalent linkage deliver antimiR-21 for gastric cancer therapy.  Polymer Chemistry,  (26): (4352-4366).  [PMID:] [10.1039/C6PY00651E]
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61. Peisheng Zhang, Xiao-fang Jiang, Xuezheng Nie, Yong Huang, Fang Zeng, Xitao Xia, Shuizhu Wu.  (2015)  A two-photon fluorescent sensor revealing drug-induced liver injury via tracking γ-glutamyltranspeptidase (GGT) level in vivo.  BIOMATERIALS,      [PMID:26706475] [10.1016/j.biomaterials.2015.11.047]
62. Ming Wang, Zhi Wang, Nan Li, Jiayou Liao, Song Zhao, Jixiao Wang, Shichang Wang.  (2015)  Relationship between polymer–filler interfaces in separation layers and gas transport properties of mixed matrix composite membranes.  JOURNAL OF MEMBRANE SCIENCE,      [PMID:] [10.1016/j.memsci.2015.08.019]
63. Sen Lin, Fangfang Deng, Ping Huang, Lingli Li, Lei Wang, Qing Li, Ling Chen, Hao Chen, Kaihui Nan.  (2015)  A novel legumain protease-activated micelle cargo enhances anticancer activity and cellular internalization of doxorubicin.  Journal of Materials Chemistry B,  (29): (6001-6012).  [PMID:32262656] [10.1039/C5TB00736D]
64. Zhanhui Wang, Xiao Liang, Kai Wen, Suxia Zhang, Chenglong Li, Jianzhong Shen.  (2015)  A highly sensitive and class-specific fluorescence polarisation assay for sulphonamides based on dihydropteroate synthase.  BIOSENSORS & BIOELECTRONICS,      [PMID:25775967] [10.1016/j.bios.2015.03.016]
65. Sui Wang, Shasha Lv, Wenwen Wu, Zhiyong Guo.  (2014)  A Novel Electrochemiluminescence Sensor for Sensitive Determination of Carbaryl Based on Solid Phase Microextraction at NH2–Graphene–Nafion Modified Electrode.  AUSTRALIAN JOURNAL OF CHEMISTRY,  68  (5): (793-799).  [PMID:] [10.1071/CH14379]
66. Yinan Zhao, Shubiao Zhang, Yuan Zhang, Shaohui Cui, Huiying Chen, Defu Zhi, Yuhong Zhen, Shufen Zhang, Leaf Huang.  (2014)  Tri-peptide cationic lipids for gene delivery.  Journal of Materials Chemistry B,  (1): (119-126).  [PMID:25580248] [10.1039/C4TB01312C]
67. Weiwei Jiang, Yuwei Cheng, Lei Hou, Ying Huang, Sizhen Wang, Yunchang Zhang, Tao Jiang, Feng Yang, Zhiqiang Ma.  (2024)  A dual-prodrug nanogel combining Vorinostat and Pyropheophorbide a for a high efficient photochemotherapy.  INTERNATIONAL JOURNAL OF PHARMACEUTICS,      [PMID:38977163] [10.1016/j.ijpharm.2024.124422]
68. Zhiyong Shi, Miaomiao Liu, Xiaowen Zhang, Jingyang Wang, Junwei Zhang, Zeyan Peng, Li Meng, Ruijing Wang, Lihong Guo, Qiang Zhang, Jing Li, Liang Yang, Jie Liu, Yang Xu, Jie Yan, Jianlin Cui, Shan Ren, Yang Gao, Yanming Wang, Zhi Qi.  (2024)  A novel selenium analog of HDACi-based twin drug induces apoptosis and cell cycle arrest via CDC25A to improve prostate cancer therapy.  Theranostics,      [PMID:38948069] [10.7150/thno.92119]
69. Wang Jun, Yang Hai-yan, Fan Jia-jia, Xu Zi-Han, Pang Zai-hui, Feng Yuan, Wei Na.  (2024)  A QuEChERS method based on octadecyl-bonded hectorite for the determination of ten mycotoxins in yak ghee.  ANALYTICAL SCIENCES,      [PMID:39259471] [10.1007/s44211-024-00667-8]
70. Jun-Yi Zhou, Yan-Qing Chen, Guang Hu, Haiyu Zhao, Jian-Bo Wan.  (2024)  An integrated strategy for in-depth profiling of N-acylethanolamines in biological samples by UHPLC-HRMS.  ANALYTICA CHIMICA ACTA,      [PMID:39396319] [10.1016/j.aca.2024.343262]
71. Xingdan Wang, Zhenghu Min, Xiaoqiu Yang, Qiwei Zhang, Qi Zheng.  (2025)  Analysis of phosphorylation site occupancy of peptides based on a chemical derivatization method.  Analytical Methods,  17  (8): (1923-1929).  [PMID:39927441] [10.1039/D4AY02208D]
72. Zhang Sheng, Wu Bingjie, Song Bo, Chen Tao, Li Qing, Wu Guangshun, Chen Lei.  (2025)  Biomimetic Construction of PBO Fiber Hierarchical Reinforcement with Simultaneously Enhanced Interfacial Properties and Atomic Oxygen Erosion Resistance for Advanced Composites.  FIBERS AND POLYMERS,      [PMID:] [10.1007/s12221-025-00912-5]
73. Pang Chaohai, Xu Yuan, Ma Xionghui, Li Shuhuai, Zhou Shengfu, Tian Hai, Wang Mingyue, Han Bingjun.  (2024)  Design, synthesis, and evaluation of novel arecoline-linked amino acid derivatives for insecticidal and antifungal activities.  Scientific Reports,  14  (1): (1-9).  [PMID:38658769] [10.1038/s41598-024-60053-2]
74. Qiao Lin, Changsheng Li, Yuhua Wang, Yanqing Zhu, Yueqing Gu.  (2024)  Discovery of Near-Infrared Heptamethine Cyanine Probes for Imaging-Guided Surgery in Solid Tumors.  JOURNAL OF MEDICINAL CHEMISTRY,      [PMID:38560986] [10.1021/acs.jmedchem.4c00010]
75. Yunxia Yuan, Bingqing Chi, Jiajia Fan, Ying Wang, Gan Luo, Xiaoyan Gao.  (2025)  Enhancing the Accuracy of Identification and Relative Quantification of Unsaturated Fatty Acids in Serum via a Stable Isotope-Labeled Double Derivatization Strategy.  ANALYTICAL CHEMISTRY,      [PMID:40019293] [10.1021/acs.analchem.4c06375]
76. Yushan Wu, Hantian Lu, Faxiang Qin, Shan Yang, Peng Xu, Hua-Xin Peng.  (2024)  Establishing interphase with “rigid-flexible coupling” crosslinked network by supramolecular structure to improve interfacial properties of high-modulus carbon fiber composites.  COMPOSITES PART B-ENGINEERING,      [PMID:] [10.1016/j.compositesb.2024.111968]
77. Jingxuan Yang, Yi Wu, Ziye Jiang, Lili Jiao, Yang Wang.  (2025)  Fecal fatty acid profile reveals the therapeutic effect of red ginseng acidic polysaccharide on type 2 diabetes mellitus in rats.  JOURNAL OF FOOD SCIENCE,  90  (1): (e70015).  [PMID:39832227] [10.1111/1750-3841.70015]
78. Jiahui Zhang, Dongxin Zhao, Kui Lu, Libo Yuan, Heng Du.  (2024)  Gelation Behavior and Drug Sustained-Release Properties of a Helix Peptide Organohydrogel with pH Responsiveness.  LANGMUIR,      [PMID:38591865] [10.1021/acs.langmuir.4c00266]
79. Sai Qiao, Xinxin Zheng, Yuanyuan Ou, Ting Li, Xue Zhao, Jia Quan, Xinfeng Zhao, Qian Li.  (2024)  Highly efficient GPCR immobilization with enhanced fouling resistance, salt tolerance, and chromatographic performance.  COLLOIDS AND SURFACES B-BIOINTERFACES,      [PMID:38417347] [10.1016/j.colsurfb.2024.113818]
80. Haoran Xu, Zhuoyi Ye, Xin Gao, Yue Dai, Yang Luo, Zhihao Han, Yueqing Gu.  (2024)  Repurposing GnRH-A as a Near-Infrared Fluorescent Probe for Diagnosis and Surgical Navigation of Breast Cancer Tumors and Metastases.  JOURNAL OF MEDICINAL CHEMISTRY,      [PMID:38995618] [10.1021/acs.jmedchem.4c01142]
81. Wen Nie, Feiran Xu, Kai Zhou, Jieying Deng, Ying Wang, Baocai Xu.  (2024)  Stability and transepithelial transport of oligopeptide (KRQKYD) with hepatocyte-protective activity from Jinhua ham in human intestinal Caco-2 monolayer cells.  Food Science and Human Wellness,      [PMID:] [10.26599/FSHW.2022.9250127]
82. Xiao-Min Cao, Yuan-Qiu Cheng, Meng-Meng Chen, Shun-Yu Yao, An-Kang Ying, Xiu-Zhen Wang, Dong-Sheng Guo, Yue Li.  (2024)  Sulfonated Azocalix[4]arene-Modified Metal–Organic Framework Nanosheets for Doxorubicin Removal from Serum.  Nanomaterials,  14  (10): (864).  [PMID:38786820] [10.3390/nano14100864]
83. Lixia Guo, Yafei Tian, Liang Zhou, Shiyue Kang, Chengwu Zhang, Wen Liu, Haipeng Diao, Liheng Feng.  (2024)  Tailored Phototherapy Agent by Infection Site In Situ Activated Against Methicillin-Resistant S. aureus.  Advanced Healthcare Materials,      [PMID:38728574] [10.1002/adhm.202400593]
84. Shuang Yi, Yinfeng Xu, Yuqing Cao, Hui Mao, Gang He, Huaqiang Shi, Xiaoling Li, Hua Dong.  (2024)  The decisive role of filtration reducers’ surface charge in affecting drilling fluid filtration performance.  JOURNAL OF MOLECULAR LIQUIDS,      [PMID:] [10.1016/j.molliq.2024.125505]
85. Chunsen Yuan, Taotao Jin, Hangke Lei, Juanjuan Liu, Wendan Pu, Yang Zhang, Chenwen Li, Dingde Huang, Jianxiang Zhang, Jiawei Guo.  (2025)  Self-illuminating liposome-derived in situ triggerable photodynamic therapy combining radionuclide therapy for synergistic treatment of lung cancer.  Acta Pharmaceutica Sinica B,      [PMID:41132850] [10.1016/j.apsb.2025.06.026]
86. Chao Zhao, Xiaoyan Huang, Zhuoyang Wu, Wanlu Sun, Yi Pan, Yi Liu.  (2025)  pH-Responsive Self-Assembled Upconversion Photosensitizer and RSL3 Synergistically Induce Tumor Ferroptosis.  JOURNAL OF MEDICINAL CHEMISTRY,      [PMID:40665790] [10.1021/acs.jmedchem.5c01339]
87. Xin-Ze Wu, Kai-Wen Tan, Xu Zhang, Jun-Jie Tan, Na An, Fang Cong, Wenbin Wu, Azamat Temerdashev, Quan-Fei Zhu, Hong Wang, Yu-Qi Feng.  (2025)  One-Step Labeling and Purification: Accelerating FAHFA Detection in Vegetable Oils via Chemoselective Probe-Assisted LC–MS.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:40765362] [10.1021/acs.jafc.5c06401]
88. Lianru Ma, Wei Wang, Qian Zhang, Yongrui He.  (2025)  Enhancing the Interfacial Properties of Carbon Fiber/Epoxy Resin Composites by Constructing a Rigid–Flexible Structure of Carbon Nanotubes and Polyether Amine Onto Carbon Fibers.  POLYMER COMPOSITES,      [PMID:] [10.1002/pc.70167]
89. Jie Hu, Yuheng Zhang, Xin Wang, Xuezhong Gong, Zhongjie Cheng, Yao Wang, Sui Mao, Alexander Fainleib, Peter Strizhak, Jianguo Tang.  (2025)  Strong Hierarchical Reinforcement Effect of Fe3O4-Terminated Nanostructures of Finely Rebuilt Carbon Nanotubes at Short Carbon Fiber Surface on Epoxy Composites.  ACS Applied Polymer Materials,      [PMID:] [10.1021/acsapm.5c01187]
90. Jingxuan Yang, Yi Wu, Liang Zhao, Meng Li, Wenjun Guo, Yajuan Xu, Yang Wang.  (2025)  Chemical Derivatization-Based Liquid Chromatography-Mass Spectrometry Method for Fatty Acid Profiling in Biological Samples.  JOURNAL OF SEPARATION SCIENCE,  48  (7): (e70211).  [PMID:40614163] [10.1002/jssc.70211]
91. Dongyang Miao, Yuanyuan Song, Zhiwei Fan, Chong Ji, Jiao Hua, Xinglei Zhao, Jichao Zhang, Chaobo Huang, Ranhua Xiong.  (2025)  Phenylboronic acid-functionalized photothermal nanofibers for enhanced suspension cell adhesion and intracellular delivery.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,      [PMID:40829235] [10.1016/j.jcis.2025.138696]
92. Haizhu Shi, Qian Chen, Shuling Yang, Chungu Zhang, Yu Wan, Shun Feng, Lian-Hai Shan.  (2025)  Biomimetic Epitope-Imprinted Nanogatekeepers on Mesoporous Silica for Tumor-Targeted Drug Delivery.  ACS Applied Bio Materials,      [PMID:40792690] [10.1021/acsabm.5c01295]
93. Yi Wu, Yang Wang.  (2025)  An Improved Metabolomics Workflow Enables Untargeted Data Acquisition and Targeted Data Analysis Using Liquid Chromatography–Mass Spectrometry.  JOURNAL OF PROTEOME RESEARCH,      [PMID:40771120] [10.1021/acs.jproteome.5c00427]
94. Xueling Long, Siyi Li, Yuxiang Ma, Yuting Cao, Shaoping Sun.  (2025)  Octaarginine nanocomplex encapsulated with hyaluronic acid-modified CuS for enhanced transdermal delivery of insulin.  JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY,      [PMID:] [10.1016/j.jddst.2025.107550]
95. Hui Xiong, Jingxue Yan, Jun Zhang, Yuhang Jiang, Xiaoqin Chi, Hongyu Lin, Jinhao Gao.  (2025)  Cinnamaldehyde-Containing Organoarsenic Prodrug with Synergistic Anticancer Activity via Redox Dyshomeostasis.  MOLECULAR PHARMACEUTICS,      [PMID:40948450] [10.1021/acs.molpharmaceut.5c00778]
96. Qianqian Qi, Zhanyu Zhang, Dun Wang.  (2025)  GSH-responsive paclitaxel prodrug used in chemotherapy in combination with photodynamic therapy.  BIOORGANIC CHEMISTRY,      [PMID:40007348] [10.1016/j.bioorg.2025.108289]
97. Zhang Xiandi, Jiang Xiang’er, Wang Yun, Chen Qinzhen, Jiang Hao, Zhang Hu, Beltran Antoni, Yang Weiya, Chen Tai, Liang Chenglong, Cheng Ning, Huang Yun, Ding Guqiao, Xie Chengwang, Gao Nanfeng, Liu Juntao, Xu Wei, Huang Jinlei, Cai Dong, Zhu Lihao, Mo Songjin, Shen Mengzhe, Zhang Wenwei, Lehner Ben, Ni Ming, Wang Jian, Xu Xun, Shen Yue.  (2025)  Scaling DNA synthesis with a microchip-based massively parallel synthesis system.  NATURE BIOTECHNOLOGY,      [PMID:41034496] [10.1038/s41587-025-02844-0]
98. Danping Wang, Hao Chen, Binglei Song, Tingting Yan, Zhaolan Zhai, Xiaomei Pei, Zhenggang Cui.  (2020)  Supramolecular Hydrogels with Chiral Nanofibril Structures Formed from β-Cyclodextrin and a Rosin-Based Amino Acid Surfactant.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:32816467] [10.1021/acs.jafc.0c03748]
99. Shicheng Pei, Zhaohan Liu, Qishu Jiao, Qiling Jin, Xuan Luo, Yuanyuan Liu, Shuyao Zhou, Shuqin Pang, Xiaoxing Wu, Keming Xu, Wenying Zhong.  (2025)  Self-Reporting Ratiometric AIEgen-Peptide Nanoprobes for Activatable Chemotherapy and Noninvasive Imaging of Therapeutic Outcomes.  JOURNAL OF MEDICINAL CHEMISTRY,      [PMID:40170557] [10.1021/acs.jmedchem.5c00372]
100. Han Yang, Min Liu, Jingwen Jia, XiaoFang Li, Siyi Liu, Jingya Xiu, Jiulong Zhang, Xiuli Zhao.  (2025)  Biomimetic carrier-free nanoplatform based on natural polyphenols and siRNA for targeted therapy in rheumatoid arthritis.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.162651]
101. Zi-Jin Wei, Kai Long, Chang Yin, Xinxin Yuan, Mengjie Sun, Wei Wang, Zhi Yuan.  (2025)  One-Pot Synthesis of Enhanced Dye-Sensitized Persistent Luminescence Nanoparticles to Alleviate Concentration Quenching.  Journal of Materials Chemistry B,      [PMID:40376842] [10.1039/D5TB00312A]
102. Na An, Peng-Cheng Mei, Ao Li, Xiu-Feng Fu, Xin-Ze Wu, Han-Peng Jiang, Quan-Fei Zhu, Yu-Qi Feng.  (2025)  Derivatization-Assisted Acoustic Ejection Mass Spectrometry for High-Throughput FAHFA Prescreening.  ANALYTICAL CHEMISTRY,      [PMID:40305168] [10.1021/acs.analchem.5c01004]
103. Dong Xiang, Chao Chen, Guoqian Xie, Yusheng Gong, Jingxiong Ma, Eileen Harkin-Jones, Menghan Wang, Libing Liu, Yuanpeng Wu, Chunxia Zhao, Hui Li.  (2025)  Mechanical property enhancement of basalt fiber-reinforced epoxy composites via construction of an organic/inorganic hybrid interface.  Progress in Natural Science-Materials International,      [PMID:] [10.1016/j.pnsc.2025.01.002]
104. He Jianan, Cai Jianxun, Zhang Jingjing, Li Yang, Wei Kunpeng, Liu Chenshu, Yan Leye, Hu Xinyan, Huang Lin, Gan Hairun, Wang Dashuai, Li Bing, Zhang Huitao, Pang Pengfei.  (2025)  Enhanced atherosclerosis molecular imaging and therapy with collagen hybridizing peptide functionalized albumin nanoparticles.  JOURNAL OF NANOBIOTECHNOLOGY,  23  (1): (1-15).  [PMID:41152999] [10.1186/s12951-025-03721-3]
105. Jie Hu, Yihong Zhao, Nan Chen, Xuezhong Gong, Yao Wang, Jun Li, Ihor Rusetskyi, Mykhailo Danilov, Olga Grigoryeva, Alexander Fainleib, Petro Stryzhak, Jianguo Tang.  (2025)  Strongly enhanced mechanical and electromagnetic shielding properties of short carbon fiber reinforced epoxy composites by a comprehensive “absorption-transfer” interface.  Journal of Materials Research and Technology-JMR&T,      [PMID:] [10.1016/j.jmrt.2025.10.248]
106. Xingran Kou, Yuxin Yang, Tingting Yan, Yue Wei.  (2025)  Injectable gel emulsions stabilized by tubular–fibrous networks self-assembled from an ursolic acid-based amphiphile.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,      [PMID:41371177] [10.1016/j.jcis.2025.139639]
107. Yaqi Wang, Ping Shu, Mei Lv, Yonghao Xing, Haoran Zhang, Xiaojing Yan, Bo Wang, Tingting Huang, Minfeng Fang.  (2025)  A general strategy to screen and evaluate antitussive, anti-inflammatory, and expectorant active components from raw and honey-fired Farfarae Flos based on β2-AR/CysLT1R/M3R chromatography and mice models.  JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,      [PMID:41494282] [10.1016/j.jpba.2025.117331]
108. Zena Chen, Zhihang Liao, Fangning Du, Xiang Che, Likun Wang, Wei Shi, Changmin Yu, Naidi Yang.  (2025)  One-Step Facile Synthesis of a Cationic Photosensitizer with Electrostatic Anchoring of Bacteria for Photodynamic Therapy of MRSA-Infected Wounds.  ACS Applied Materials & Interfaces,      [PMID:41448952] [10.1021/acsami.5c18942]
109. Qin Ke, Cui Jiaqi, Zhang Yajing, Zhao Wuduo, Zhang Qidong, Xi Hui, Fu Yingjie, Wang Dingzhong.  (2026)  N,N-Diethylethylenediamine for on-tissue derivatization: a novel strategy for in situ MALDI imaging of fatty acids.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,      [PMID:41540210] [10.1007/s00216-026-06320-9]
110. Tingting Yan, Minglin Wang, Danping Wang, Binglei Song, Ming Liu, Lulu Zhou.  (2026)  Self-Assembly of a Rosin-Derived Glycosylated Surfactant into Chiral Wormlike Micelles with Unusual Viscoelasticity.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:41670226] [10.1021/acs.jafc.5c17162]
111. Hongkai Fang, Jingxuan Zhang, Jialin Xing, Yuebin Dai, Yanzhong Hao, Wenjing Wang, Zhiyu Kuang, Mingyang Han, Zhonggui He, Bingjun Sun, Jin Sun.  (2026)  Optimizing doxorubicin prodrug albumin nanoparticles through tailored alkyl chain lengths and optimized linker chemistry.  Nano Today,      [PMID:] [10.1016/j.nantod.2026.103034]
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