Interferon alpha/beta receptor 1 Mouse mAb - Primary antibody, specific to Interferon alpha/beta receptor 1, Mouse IgG1

Cat. No.: Ab110956

GRADE & PURITY Carrier Free, Validated, Low Endotoxin, Azide Free, PBS Only, ≥95%(SDS-PAGE&HPLC), See COA

Application

Blocking, ELISA, Flow Cytometry, Functional Assay, IP, WB

Host species

Mouse

Reactive species

Mouse

Isotype

Mouse IgG1

Clone Number

MAR1-5A3

Conjugation

Unconjugated

Descripción general

Mouse anti Mouse Interferon alpha/beta receptor 1 Antibody, Monoclonal (MAR1-5A3), could be used for IP, WB, Flow, ELISA, Blocking, Functional Assays and so on.
Application
Flow: ≤ 1.0µg/100w cells
IP: Use at an assay dependent concentration.
WB: Use at an assay dependent concentration.
ELISA: Use at an assay dependent concentration.
Blocking: Use at an assay dependent concentration.
Functional Assays: Use at an assay dependent concentration.
Protein Function
Associates with IFNAR2 to form the type I interferon receptor. Receptor for interferons alpha and beta. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta-subunits themselves.

Specifications

Product Name

Interferon alpha/beta receptor 1 Mouse mAb - Primary antibody, specific to Interferon alpha/beta receptor 1, Mouse IgG1

Sinónimos

Ifar | Ifrc | Ifnar | Infar | alpha-type antiviral protein | AVP | beta-type antiviral protein | CRF2-1 | Cytokine receptor class-II member 1 | Cytokine receptor family 2 member 1 | human interferon-alpha receptor (HuIFN-alpha-Rec)10IFRC | IFN-alpha/beta

Especificaciones y pureza

Carrier Free, Low Endotoxin, Azide Free, Validated, PBS Only, ≥95%(SDS-PAGE&HPLC), See COA

Especies hospedadoras

Mouse

Especificidad

Interferon alpha/beta receptor 1

Inmunógeno

This antibody was produced by In vivo genetic immunization of IFNAR1 knockout mice with a plasmidencoding the extracellular domain of murine IFNAR1.

Conjugación

Unconjugated

Grado

Azide Free, Carrier Free, Low Endotoxin, PBS Only, Validated

Isotipo

Mouse IgG1

Tipo de cadena ligera

kappa

SDS-PAGE

150 kDa

Método de purificación

Protein A purified

Concentración

See COA

Almacenamiento y envío

Forma

Liquid

Condiciones de almacenamiento de almacenamiento

Store at -20°C,Avoid repeated freezing and thawing

Enviado en

Ice chest + Ice pads

Estabilidad y almacenamiento

Store at 4°C short term (1-2 weeks). Store at -20°C long term (12 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Imágenes

Flow Cytometry: Interferon alpha/beta receptor 1 Mouse mAb (Ab110956)

Interferon alpha/beta receptor 1 Mouse mAb (Ab110956) - Flow Cytometry
Flow Cytometry analysis of mouse splenocytes cells labelling Interferon alpha/beta receptor 1 with Interferon alpha/beta receptor 1 Mouse mAb (Ab110956) conjugated with biotin (right panel) at 0.5 μg/mL for 1 hour at 4°C, compared with Mouse IgG Isotype Control Antibody (Biotin) (Ab180306) (left panel) and detected with SA-PE (rp156150).

Flow Cytometry: Interferon alpha/beta receptor 1 Mouse mAb (Ab110956)

Interferon alpha/beta receptor 1 Mouse mAb (Ab110956) - Flow Cytometry
Flow Cytometry analysis of mouse splenocytes cells labelling Interferon alpha/beta receptor 1 (red) with Interferon alpha/beta receptor 1 Mouse mAb (Ab110956) conjugated with biotin at 0.5 μg/mL for 1 hour at 4°C, and detected with SA-PE (rp156150). Blue - Mouse IgG Isotype Control Antibody (Biotin) (Ab180306). Black - Unlabelled control, cells without incubation with primary antibody.

Aplicación

• Aplicación: Dilution info
• Flow Cytometry:

  ≤1.0µg/100w cells;

• WB:

  Use at an assay dependent concentration.;

• Blocking:

  Use at an assay dependent concentration.;

• Functional Assay:

  Use at an assay dependent concentration.;

• IP:

  Use at an assay dependent concentration.

• ELISA:

  Use at an assay dependent concentration.;

Objetivos asociados (humanos)

IFNAR1 Tclin Interferon alpha/beta receptor 1 (0 Activities)

Discover Target: IFNAR1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

IFNAR1 Tclin Interferon-alpha/beta receptor alpha chain (50 Activities)

Discover Target: IFNAR1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de acción