Lesabelimab (anti-PD-L1) - Primary antibody, specific to CD274, Human IgG1

CAS: 2475402-56-1 Cat. No.: Ab182969
Disponible para pedir
GRADE & PURITY Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. RUO ? Research Use Only — for laboratory research, not diagnostic or therapeutic use. Use in R&D; do not use in clinical diagnosis or patient treatment. ≥95%(SDS-PAGE&SEC-HPLC) See COA
Application
Animal Model, ELISA, Flow Cytometry, Functional Assay
Host species
Human
Reactive species
Human
Isotype
Human IgG1
Conjugation
Unconjugated
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
100μg
Ab182969-100μg
10
92,90US$
1mg
Ab182969-1mg
4
571,90US$
5mg
Ab182969-5mg
1
1.499,90US$
10mg
Ab182969-10mg
1-2 wks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
2.399,90US$
Enter a quantity for the sizes you want to add.
🧪

Why this grade

RUO, ≥95%(SDS-PAGE&SEC-HPLC), Ver COA Animal Free,RUO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Conservar a -80°C,Evitar la congelación y descongelación repetidas Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Lesabelimab (anti-PD-L1) es un anticuerpo monoclonal inmunoglobulina G1-kappa anti-CD274. El CD274 es un ligando de punto de control inmunitario que reprime la inmunidad antitumoral mediante la interacción con el receptor PDCD1.
Pureza
≥95% (SDS-PAGE&SEC)
Nivel de endotoxinas
< 1,0EU/mg

Specifications

Product Name
Lesabelimab (anti-PD-L1) - Primary antibody, specific to CD274, Human IgG1
Sinónimos
Anticuerpo B7 H | Anticuerpo B7 H1 | Anticuerpo B7 homólogo 1 | Anticuerpo B7-H1 | Anticuerpo B7H1 | Anticuerpo CD 274 | Anticuerpo CD-274 | Anticuerpo CD274 | Anticuerpo antígeno CD274 | Anticuerpo molécula CD274 | Anticuerpo MGC142294 | Anticuerpo MGC14
Especificaciones y pureza
RUO, ≥95%(SDS-PAGE&SEC-HPLC), Ver COA
Especies hospedadoras
Human
Especificidad
CD274
Conjugación
Unconjugated
Grado
Animal Free, RUO
Tipo de acción
INHIBITOR
Isotipo
Human IgG1
Tipo de cadena ligera
kappa
SDS-PAGE
25.8 kDa (Light Chain) & 49.1 kDa (Heavy Chain), under reducing conditions; 195.9 kDa, under non-reducing conditions.
Método de purificación
Protein A purified
Concentración
See COA
CAS
2475402-56-1
Almacenamiento y envío
Forma
Líquido
Condiciones de almacenamiento de almacenamiento
Conservar a -80°C,Evitar la congelación y descongelación repetidas
Enviado en
Dry ice packs + Cold packs
Estabilidad y almacenamiento
Almacenar a -80℃ durante 24 meses. Tras la recepción, se recomienda alícuota. Evite el ciclo de congelación/descongelación.
Imágenes

Lesabelimab (anti-PD-L1) (Ab182969) - Flow Cytometry
Flow Cytometry analysis of 500 ng/mL Ionomycin (I139530) and 10 ng/mL PMA (P408905) co-stimulated Jurkat cells (24h) labelling PD-L1 (red) with Lesabelimab (anti-PD-L1) (Ab182969). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Lesabelimab (anti-PD-L1) (Ab182969) - ELISA
Immobilized Recombinant Human PD-L1 protein (rp169666) at 1.0 μg/mL can bind Lesabelimab (anti-PD-L1) (Ab182969) with the EC₅₀ of 172.4 ng/mL.

Lesabelimab (anti-PD-L1) (Ab182969) - SEC
The purity of Lesabelimab (anti-PD-L1) (Ab182969) is more than 95% verified by HPLC.

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Objetivos asociados (humanos)
CD274 Tclin Programmed cell death 1 ligand 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot NumberCertificate TypeFechaArticulo
ZJ24F0606993Certificate of AnalysisApr 16, 2026 Ab182969
ZJ24F0606994Certificate of AnalysisApr 16, 2026 Ab182969
ZJ24F0606995Certificate of AnalysisApr 16, 2026 Ab182969
Preguntas frecuentes y artículos
Calculadoras de soluciones
Reseñas

Reseñas de cliente

Need help choosing the grade?

Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

View Animal Free grade guide → View RUO grade guide →

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