GRADE & PURITYValidated?Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated.ExactAb™?ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications.1.0 mg/mL
ExactAb™, Validated, 1.0 mg/mL ExactAb™,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -20°C,Avoid repeated freezing and thawing Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general
Mouse anti Human Lyn Antibody, Monoclonal (1C8-H3-G6), could be used for WB and so on. Application: WB: 1/500-1/1000 Protein Function Down regulates expression of stem cell growth factor receptor (KIT). Acts as an effector of EpoR (erythropoietin receptor) in controlling KIT expression and may play a central role in erythroid differentiation during the switch between proliferation and maturation (By similarity). Acts as a positive regulator of cell movement while negatively regulating adhesion to stromal cells by inhibiting the ICAM-1-binding activity of beta-2 integrins. Acts as the mediator that relays suppressing signals from the chemokine receptor CXCR4 to beta-2 integrin LFA-1 in hematopoietic precursors. Involved in induction of stress-activated protein kinase (SAPK), but not ERK or p38 MAPK, in response to genotoxic agents. Induces SAPK by a MKK7- and MEKK1-dependent mechanism. The LYN -> MEKK1 -> MKK7 -> SAPK pathway is functional in the induction of apoptosis by genotoxic agents.
Specifications
Product Name
Lyn Mouse mAb - Primary antibody, specific to LYN, Mouse IgG1
Sinónimos
AA407514antibody | EC 2.7.10.2 antibody | FLJ26625 antibody | Hck 2 antibody | JTK 8 antibody | JTK8 antibody | Lck/Yes related novel protein tyrosine kinase antibody | LYN antibody | LYN proto oncogene, Src family tyrosine kinase antibody | LYN_HUMAN ant
Especificaciones y pureza
ExactAb™, Validated, 1.0 mg/mL
Especies hospedadoras
Mouse
Especificidad
LYN
Inmunógeno
Purified recombinant human Lyn protein fragments expressed in Ecoli (AA 8-238)
Control positivo
WB: Ramos, Raji, K562, HeLa and A431 cell lysates.
Conjugación
Unconjugated
Grado
ExactAb™, Validated
Isotipo
Mouse IgG1
SDS-PAGE
150 kDa
Método de purificación
Protein G purified
Concentración
1.0 mg/mL
Almacenamiento y envío
Forma
Liquid
Condiciones de almacenamiento de almacenamiento
Store at -20°C,Avoid repeated freezing and thawing
Enviado en
Ice chest + Ice pads
Estabilidad y almacenamiento
Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Imágenes
Lyn Mouse mAb (Ab113790) - Western Blot All lanes: Lyn Mouse mAb (Ab113790) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab138040) at 1/20000 dilution
Predicted band size: 59 kDa Observed band size: 55 kDa Exposure time: 47.5 s
Aplicación
Aplicación
Dilution info
WB
1/500-1/1000
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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