MUC1/CD227 Mouse mAb - Primary antibody, specific to MUC1/CD227

Cat. No.: Ab116377

GRADE & PURITY Carrier Free, Validated, ExactAb™, Azide Free, PBS Only, ≥95%(SDS-PAGE), See COA

Application

Animal Model, Flow Cytometry, Functional Assay, IF/ICC, IHC, WB

Host species

Mouse

Reactive species

Human

Isotype

Mouse IgG3

Clone Number

C595 (NCRC48)

Conjugation

Unconjugated

Descripción general

Mouse anti Human MUC1/CD227 Antibody, Monoclonal (C595 (NCRC48)), could be used for IHC, IF/ICC, WB, Flow Cytometry, in vivo administration in mouse xenograft models, in vitro cell cytotoxicity assay and so on.

Specifications

Product Name

MUC1/CD227 Mouse mAb - Primary antibody, specific to MUC1/CD227

Sinónimos

MCD | PUM | MCKD | MCKD1 | ADMCKD | ADTKD2 | Ca15-3 | ADMCKD1 | CA 15-3 | MUC-1/X | MUC-1/SEC | Breast carcinoma-associated antigen DF3 | Carcinoma-associated mucin | CD227 antigen | CD227 | DF3 antigen | EMA | Episialin | H23 antigen | H23AG | KL-6 | MAM

Especificaciones y pureza

Carrier Free, ExactAb™, Azide Free, Validated, PBS Only, ≥95%(SDS-PAGE), See COA

Mecanismos bioquímicos y fisiológicos

The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. The beta subunit contains a C-terminal domain which is involv

Especies hospedadoras

Mouse

Especificidad

MUC1/CD227

Inmunógeno

Purified human MUC1

Conjugación

Unconjugated

Grado

Azide Free, Carrier Free, ExactAb™, PBS Only, Validated

Tipo de cadena ligera

kappa

SDS-PAGE

150 kDa

Método de purificación

Protein A purified

Concentración

See COA

Almacenamiento y envío

Forma

Liquid

Condiciones de almacenamiento de almacenamiento

Store at 2-8°C,Do not freeze

Enviado en

Wet ice,Do not freeze

Estabilidad y almacenamiento

Shipped at 4°C. Store at 4°C long term (12 months). Do not freeze. Upon receipt, it is recommended to aliquot.

Imágenes

Flow Cytometry: MUC1/CD227 Mouse mAb (Ab116377)

MUC1/CD227 Mouse mAb (Ab116377) - Flow Cytometry
Flow Cytometry analysis of MCF7 cells labelling MUC1/CD227 (red) with MUC1/CD227 Mouse mAb (Ab116377) at 0.1 μg/mL for 1 hour at 4°C. Goat Anti-Mouse IgG (PE) (Ab179006) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, mouse IgG (Ab170221). Black - Unlabelled control, cells without incubation with primary antibody.

Aplicación

• Aplicación: Dilution info
• WB:

  Use at an assay dependent concentration.;

• IHC:

  Use at an assay dependent concentration.;

• Flow Cytometry:

  Use at an assay dependent concentration.

• IF/ICC:

  Use at an assay dependent concentration.;

• in vivo administration in mouse xenograft models:

  Use at an assay dependent concentration. ;

• in vitro cell cytotoxicity assay:

  Use at an assay dependent concentration. ;

Objetivos asociados (humanos)

MUC1 Tchem Mucin-1 (0 Activities)

Discover Target: MUC1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Mecanismos de acción